Improved In Vitro Model for Intranasal Mucosal Drug Delivery: Primary Olfactory and Respiratory Epithelial Cells Compared with the Permanent Nasal Cell Line RPMI 2650

Effect of lipopolysaccharide on diesel exhaust particle-induced junctional dysfunction in primary human nasal epithelial cells

(2019) Nahyun Kim et al.   ENVIRONMENTAL POLLUTION

Pharmacological characterization of the 3D MucilAir™ nasal model

(2019) Clément Mercier et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Mechanism of intranasal drug delivery directly to the brain

(2018) Tyler P. Crowe et al.   LIFE SCIENCES

Pharmacological Characterization of the RPMI 2650 Model as a Relevant Tool for Assessing the Permeability of Intranasal Drugs

(2018) Clément Mercier et al.   MOLECULAR PHARMACEUTICS

Allogenic Fc Domain-Facilitated Uptake of IgG in Nasal Lamina Propria: Friend or Foe for Intranasal CNS Delivery?

(2018) Simone Ladel et al.   Pharmaceutics

Tailoring Formulations for Intranasal Nose-to-Brain Delivery: A Review on Architecture, Physico-Chemical Characteristics and Mucociliary Clearance of the Nasal Olfactory Mucosa

(2018) Stella Gänger et al.   Pharmaceutics

Drug targeting strategies into the brain for treating neurological diseases

(2018) Wilson Barnabas   JOURNAL OF NEUROSCIENCE METHODS

Is RPMI 2650 a Suitable In Vitro Nasal Model for Drug Transport Studies?

(2017) Clément Mercier et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

A comprehensive screening platform for aerosolizable protein formulations for intranasal and pulmonary drug delivery

(2017) Martina Röhm et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

In vitro nasal mucosa gland-like structure formation on a chip

(2017) Kyuhwan Na et al.   LAB ON A CHIP

Application of RPMI 2650 as a cell model to evaluate solid formulations for intranasal delivery of drugs

(2016) Vanessa S.S. Gonçalves et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Expression of P-glycoprotein in excised human nasal mucosa and optimized models of RPMI 2650 cells

(2016) Anne M. Dolberg et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Cells and Culture Systems Used to Model the Small Airway Epithelium

(2016) Rudra Bhowmick et al.   LUNG

Progress and perspectives on targeting nanoparticles for brain drug delivery

(2016) Huile Gao   Acta Pharmaceutica Sinica B

Transepithelial electrical resistance (TEER): a functional parameter to monitor the quality of oviduct epithelial cells cultured on filter supports

(2015) Shuai Chen et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Newborn pig trachea cell line cultured in air-liquid interface conditions allows a partial in vitro representation of the porcine upper airway tissue

(2014) Mario Delgado-Ortega et al.   BMC CELL BIOLOGY

The Characterization of the Human Nasal Epithelial Cell Line RPMI 2650 Under Different Culture Conditions and Their Optimization for an Appropriate in vitro Nasal Model

(2014) Mateja Erdani Kreft et al.   PHARMACEUTICAL RESEARCH

Insights into direct nose to brain delivery: current status and future perspective

(2013) Deepti Mittal et al.   DRUG DELIVERY

Direct nose to brain drug deliveryviaintegrated nerve pathways bypassing the blood–brain barrier: an excellent platform for brain targeting

(2013) Chandrakantsing Vijaysing Pardeshi et al.   Expert Opinion on Drug Delivery

An Ex Vivo Porcine Nasal Mucosa Explants Model to Study MRSA Colonization

(2013) Pawel Tulinski et al.   PLoS One

Development of primary human nasal epithelial cell cultures for the study of cystic fibrosis pathophysiology

(2012) F. de Courcey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Differentiated swine airway epithelial cell cultures for the investigation of influenza A virus infection and replication

(2012) Allen C. Bateman et al.   Influenza and Other Respiratory Viruses

The Immunologic Functions of the Neonatal Fc Receptor for IgG

(2012) Timo Rath et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Cultivation of RPMI 2650 cells as an in-vitro model for human transmucosal nasal drug absorption studies: optimization of selected culture conditions

(2012) Stephan Reichl et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

The effect of sucrose esters on a culture model of the nasal barrier

(2012) Levente Kürti et al.   TOXICOLOGY IN VITRO

Anatomical and Histological Factors Affecting Intranasal Drug and Vaccine Delivery

(2012) Sveinbjorn Gizurarson   Current Drug Delivery

Intranasal delivery of biologics to the central nervous system

(2011) Jeffrey J. Lochhead et al.   ADVANCED DRUG DELIVERY REVIEWS

Aquaporin Pathways and Mucin Secretion of Bowman's Glands Might Protect the Olfactory Mucosa

(2011) Tom T. Solbu et al.   CHEMICAL SENSES

Ex vivo study of bevacizumab transport through porcine nasal mucosa

(2011) Géraldine Samson et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Physicochemical and physiological considerations for efficient nose-to-brain targeting

(2011) Shiv Bahadur et al.   Expert Opinion on Drug Delivery

The posttranslational modification of tubulin undergoes a switch from detyrosination to acetylation as epithelial cells become polarized

(2011) Geraldine B. Quinones et al.   MOLECULAR BIOLOGY OF THE CELL

The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia

(2010) Alejandro A. Pezzulo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Air–Liquid Interface Culture of Nasal Epithelial Cells on Denuded Amniotic Membranes

(2010) Nurit Even-Tzur et al.   Cellular and Molecular Bioengineering

RPMI 2650 epithelial model and three-dimensional reconstructed human nasal mucosa as in vitro models for nasal permeation studies

(2009) Annette Wengst et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Characterisation of cell adhesion in airway epithelial cell types using electric cell-substrate impedance sensing

(2009) I. H. Heijink et al.   EUROPEAN RESPIRATORY JOURNAL

Motile Cilia of Human Airway Epithelia Are Chemosensory

(2009) A. S. Shah et al.   SCIENCE

The permeability of large molecular weight solutes following particle delivery to air-interfaced cells that model the respiratory mucosa

(2008) C.I. Grainger et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Strategies to advance translational research into brain barriers

(2008) Edward Neuwelt et al.   LANCET NEUROLOGY