Interleukin-17 Promotes Migration and Invasion of Human Cancer Cells Through Upregulation of MTA1 Expression

MTA1 is a novel regulator of autophagy that induces tamoxifen resistance in breast cancer cells

(2018) Min-Ho Lee et al.   Autophagy

MTA1 drives malignant progression and bone metastasis in prostate cancer

(2018) Avinash Kumar et al.   Molecular Oncology

FMNL1 mediates nasopharyngeal carcinoma cell aggressiveness by epigenetically upregulating MTA1

(2018) Wen-Hui Chen et al.   ONCOGENE

Metastasis-associated protein 1 (MTA1) in gastric cancer tissues is positively associated with poorer prognosis

(2018) Zhen-ye Lv et al.   PATHOLOGY RESEARCH AND PRACTICE

MTA1 promotes epithelial to mesenchymal transition and metastasis in non-small-cell lung cancer

(2017) Ke Ma et al.   Oncotarget

Effects of Th17 cells and IL-17 in the progression of cervical carcinogenesis with high-risk human papillomavirus infection

(2017) JiSen Xue et al.   Cancer Medicine

Targeting MTA1/HIF-1α signaling by pterostilbene in combination with histone deacetylase inhibitor attenuates prostate cancer progression

(2017) Nasir A. Butt et al.   Cancer Medicine

Structure, expression and functions of MTA genes

(2016) Rakesh Kumar et al.   GENE

Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition

(2016) Q Zhang et al.   ONCOGENE

Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor

(2016) Sen Liu et al.   Oncotarget

MTA1 promotes metastasis of MPM via suppression of E-cadherin

(2015) Caihua Xu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

IL-17 and insulin/IGF1 enhance adhesion of prostate cancer cells to vascular endothelial cells through CD44-VCAM-1 interaction

(2015) Chong Chen et al.   PROSTATE

Angels and demons: Th17 cells represent a beneficial response, while neutrophil IL-17 is associated with poor prognosis in squamous cervical cancer

(2015) Simone Punt et al.   OncoImmunology

Promotion of lung tumor growth by interleukin-17

(2014) Beibei Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

MTA1—a stress response protein: a master regulator of gene expression and cancer cell behavior

(2014) Rui-An Wang   CANCER AND METASTASIS REVIEWS

Oncogenic Kras Activates a Hematopoietic-to-Epithelial IL-17 Signaling Axis in Preinvasive Pancreatic Neoplasia

(2014) Florencia McAllister et al.   CANCER CELL

Insight into the Architecture of the NuRD Complex

(2014) Saad S. M. Alqarni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Human IL-17F/IL-17A Heterodimeric Cytokine Signals through the IL-17RA/IL-17RC Receptor Complex

(2014) J. F. Wright et al.   JOURNAL OF IMMUNOLOGY

T helper 17 cells play a critical pathogenic role in lung cancer

(2014) S. H. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-17 promotes development of castration-resistant prostate cancer potentially through creating an immunotolerant and pro-angiogenic tumor microenvironment

(2014) Qiuyang Zhang et al.   PROSTATE

AZD5363 Inhibits Inflammatory Synergy between Interleukin-17 and Insulin/Insulin-Like Growth Factor 1

(2014) Chong Chen et al.   Frontiers in Oncology

Insulin and IGF1 enhance IL-17-induced chemokine expression through a GSK3B-dependent mechanism: a new target for melatonin's anti-inflammatory action

(2013) Dongxia Ge et al.   JOURNAL OF PINEAL RESEARCH

Nuclear MTA1 overexpression is associated with aggressive prostate cancer, recurrence and metastasis in African Americans

(2013) Steven J. Dias et al.   Scientific Reports

Interleukin-17 Promotes Formation and Growth of Prostate Adenocarcinoma in Mouse Models

(2012) Q. Zhang et al.   CANCER RESEARCH

Role of IL-17A in the development of colitis-associated cancer

(2012) Y. S. Hyun et al.   CARCINOGENESIS

IL-17F deficiency inhibits small intestinal tumorigenesis in ApcMin/+ mice

(2011) Wook-Jin Chae et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Silencing MTA1 by RNAi reverses adhesion, migration and invasiveness of cervical cancer cells (SiHa) via altered expression of p53, and E-cadherin/β-catenin complex

(2011) Yumei Rao et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Persistent Stimulation with Interleukin-17 Desensitizes Cells Through SCF -TrCP-Mediated Degradation of Act1

(2011) P. Shi et al.   Science Signaling

TGF-  Receptor II Loss Promotes Mammary Carcinoma Progression by Th17-Dependent Mechanisms

(2011) S. V. Novitskiy et al.   Cancer Discovery

IL-17 Enhances Tumor Development in Carcinogen-Induced Skin Cancer

(2010) L. Wang et al.   CANCER RESEARCH

Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease

(2010) Reiko M. Onishi et al.   IMMUNOLOGY

Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis

(2010) W.-J. Chae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting prostate cancer angiogenesis through metastasis-associated protein 1 (MTA1)

(2010) Li Kai et al.   PROSTATE

IFN  Promotes Papilloma Development by Up-regulating Th17-Associated Inflammation

(2009) M. Xiao et al.   CANCER RESEARCH

The role of the MTA family and their encoded proteins in human cancers: molecular functions and clinical implications

(2009) Yasushi Toh et al.   CLINICAL & EXPERIMENTAL METASTASIS

Structural basis of receptor sharing by interleukin 17 cytokines

(2009) Lauren K Ely et al.   NATURE IMMUNOLOGY

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

(2009) Shaoguang Wu et al.   NATURE MEDICINE

Phenotypic Analysis of Prostate-Infiltrating Lymphocytes Reveals TH17 and Treg Skewing

(2008) K. S. Sfanos et al.   CLINICAL CANCER RESEARCH