TP53 Mutations Promote Immunogenic Activity in Breast Cancer

TP53 gain-of-function mutation promotes inflammation in glioblastoma

(2018) Seok Won Ham et al.   CELL DEATH AND DIFFERENTIATION

Lessons learned from the blockade of immune checkpoints in cancer immunotherapy

(2018) Xiaolei Li et al.   Journal of Hematology & Oncology

Immunotherapy: Cancer immunotherapy and the value of cure

(2018) Joseph C. Del Paggio   Nature Reviews Clinical Oncology

A Comprehensive Immunologic Portrait of Triple-Negative Breast Cancer

(2018) Zhixian Liu et al.   Translational Oncology

Immunogenomics Analysis Reveals that TP53 Mutations Inhibit Tumor Immunity in Gastric Cancer

(2018) Zehang Jiang et al.   Translational Oncology

Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity

(2017) Zdenek Andrysik et al.   GENOME RESEARCH

Tumor Mutational Burden as an Independent Predictor of Response to Immunotherapy in Diverse Cancers

(2017) Aaron M. Goodman et al.   MOLECULAR CANCER THERAPEUTICS

Genome-wide in vivo screen identifies novel host regulators of metastatic colonization

(2017) Louise van der Weyden et al.   NATURE

Neoantigens Generated by Individual Mutations and Their Role in Cancer Immunity and Immunotherapy

(2017) Mirjana Efremova et al.   Frontiers in Immunology

Genomic Approaches to Understanding Response and Resistance to Immunotherapy

(2016) D. A. Braun et al.   CLINICAL CANCER RESEARCH

Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells

(2016) Marco De Simone et al.   IMMUNITY

Pembrolizumab in Patients With Advanced Triple-Negative Breast Cancer: Phase Ib KEYNOTE-012 Study

(2016) Rita Nanda et al.   JOURNAL OF CLINICAL ONCOLOGY

KEGG: new perspectives on genomes, pathways, diseases and drugs

(2016) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression

(2016) Jiandong Chen   Cold Spring Harbor Perspectives in Medicine

Characterization of cytokinome landscape for clinical responses in human cancers

(2016) Henry Sung-Ching Wong et al.   OncoImmunology

Genomic profiling of CHEK2*1100delC-mutated breast carcinomas

(2015) Maarten P. G. Massink et al.   BMC CANCER

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity

(2015) Michael S. Rooney et al.   CELL

Prognostic and predictive immune gene signatures in breast cancer

(2015) Davide Bedognetti et al.   CURRENT OPINION IN ONCOLOGY

PD-L1 Expression as a Predictive Biomarker in Cancer Immunotherapy

(2015) S. P. Patel et al.   MOLECULAR CANCER THERAPEUTICS

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Combination cancer immunotherapies tailored to the tumour microenvironment

(2015) Mark J. Smyth et al.   Nature Reviews Clinical Oncology

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

(2015) Dung T. Le et al.   NEW ENGLAND JOURNAL OF MEDICINE

A p53-regulated immune checkpoint relevant to cancer

(2015) L. Zitvogel et al.   SCIENCE

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer

(2013) L Bracci et al.   CELL DEATH AND DIFFERENTIATION

Tumor STAT1 Transcription Factor Activity Enhances Breast Tumor Growth and Immune Suppression Mediated by Myeloid-derived Suppressor Cells

(2013) Laura M. Hix et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytokine patterns in patients with cancer: a systematic review

(2013) Bodo E Lippitz   LANCET ONCOLOGY

p53 increases MHC class I expression by upregulating the endoplasmic reticulum aminopeptidase ERAP1

(2013) Bei Wang et al.   Nature Communications

Inferring tumour purity and stromal and immune cell admixture from expression data

(2013) Kosuke Yoshihara et al.   Nature Communications

The HumanTLRInnate Immune Gene Family Is Differentially Influenced by DNA Stress andp53Status in Cancer Cells

(2012) Maria Shatz et al.   CANCER RESEARCH

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

(2012) Christina Curtis et al.   NATURE

Human NK Cells Are Alerted to Induction of p53 in Cancer Cells by Upregulation of the NKG2D Ligands ULBP1 and ULBP2

(2011) S. Textor et al.   CANCER RESEARCH

p53 Binds to Estrogen Receptor 1 Promoter in Human Breast Cancer Cells

(2011) Mozhgan Rasti et al.   PATHOLOGY & ONCOLOGY RESEARCH

Cancer/testis (CT) antigens: Potential targets for immunotherapy

(2009) Otavia L. Caballero et al.   CANCER SCIENCE

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

(2009) David A. Barbie et al.   NATURE

Mutant p53 Gain-of-Function in Cancer

(2009) M. Oren et al.   Cold Spring Harbor Perspectives in Biology

Tumor Suppressive Functions of p53

(2009) J. T. Zilfou et al.   Cold Spring Harbor Perspectives in Biology

CTdatabase: a knowledge-base of high-throughput and curated data on cancer-testis antigens

(2008) L. G. Almeida et al.   NUCLEIC ACIDS RESEARCH

A chemical method for fast and sensitive detection of DNA synthesis in vivo

(2008) A. Salic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA