Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia

Published 2019 View Full Article

Authors

Keywords

PCSK9, Tetrahydroprotoberberine derivatives, Low-density lipoprotein cholesterol, Lipid-lowering, PCSK9 expression, Low-density lipoprotein receptor, Total cholesterol, Hyperlipidemia hamster

Journal

Acta Pharmaceutica Sinica B

Volume -, Issue -, Pages -

Publisher

Elsevier BV

Online

2019-06-25

DOI

10.1016/j.apsb.2019.06.006

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