Zebrafish is a predictive model for identifying compounds that protect against brain toxicity in severe acute organophosphorus intoxication
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Zebrafish is a predictive model for identifying compounds that protect against brain toxicity in severe acute organophosphorus intoxication
Authors
Keywords
Zebrafish model, Severe acute organophosphorus intoxication, Brain toxicity, Neuroprotection, Antidotes
Journal
ARCHIVES OF TOXICOLOGY
Volume 91, Issue 4, Pages 1891-1901
Publisher
Springer Nature
Online
2016-09-21
DOI
10.1007/s00204-016-1851-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Targeted Gene Expression in Zebrafish Exposed to Chlorpyrifos-Oxon Confirms Phenotype-Specific Mechanisms Leading to Adverse Outcomes
- (2016) Natàlia Garcia-Reyero et al. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
- Effects of mipafox, paraoxon, chlorpyrifos and its metabolite chlorpyrifos-oxon on the expression of biomarker genes of differentiation in D3 mouse embryonic stem cells
- (2016) Miguel A. Sogorb et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Carbamate nerve agent prophylatics exhibit distinct toxicological effects in the zebrafish embryo model
- (2015) Audrey Fischer et al. NEUROTOXICOLOGY AND TERATOLOGY
- Zebrafish Models for Human Acute Organophosphorus Poisoning
- (2015) Melissa Faria et al. Scientific Reports
- Potential pharmacological strategies for the improved treatment of organophosphate-induced neurotoxicity
- (2014) Shamsherjit Kaur et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Organophosphorus Pesticide Chlorpyrifos and Its Metabolites Alter the Expression of Biomarker Genes of Differentiation in D3 Mouse Embryonic Stem Cells in a Comparable Way to Other Model Neurodevelopmental Toxicants
- (2014) Carmen Estevan et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Zebrafish models of human motor neuron diseases: Advantages and limitations
- (2014) Patrick J. Babin et al. PROGRESS IN NEUROBIOLOGY
- The Role of Glutamate and the Immune System in Organophosphate-induced CNS Damage
- (2013) Arik Eisenkraft et al. NEUROTOXICITY RESEARCH
- Functional Characterisation of the Maturation of the Blood-Brain Barrier in Larval Zebrafish
- (2013) Angeleen Fleming et al. PLoS One
- A review of experimental evidence linking neurotoxic organophosphorus compounds and inflammation
- (2012) Christopher N. Banks et al. NEUROTOXICOLOGY
- Chlorpyrifos and its metabolites alter gene expression at non-cytotoxic concentrations in D3 mouse embryonic stem cells under in vitro differentiation: Considerations for embryotoxic risk assessment
- (2012) Carmen Estevan et al. TOXICOLOGY LETTERS
- Zebrafish Eleutheroembryos Provide a Suitable Vertebrate Model for Screening Chemicals that Impair Thyroid Hormone Synthesis
- (2011) Benedicte Thienpont et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Transcriptional analysis of rat piriform cortex following exposure to the organophosphonate anticholinesterase sarin and induction of seizures
- (2011) Kimberly D Spradling et al. Journal of Neuroinflammation
- Increased expression of the chemokines CXCL1 and MIP-1α by resident brain cells precedes neutrophil infiltration in the brain following prolonged soman-induced status epilepticus in rats
- (2011) Erik A Johnson et al. Journal of Neuroinflammation
- Transcriptional Response of Zebrafish Embryos Exposed to Neurotoxic Compounds Reveals a Muscle Activity Dependent hspb11 Expression
- (2011) Nils Klüver et al. PLoS One
- Zebrafish eleutheroembryos as an alternative system for screening chemicals disrupting the mammalian thyroid gland morphogenesis and function
- (2011) Demetrio Raldúa et al. REPRODUCTIVE TOXICOLOGY
- Chlorpyrifos-Oxon Disrupts Zebrafish Axonal Growth and Motor Behavior
- (2011) Dongren Yang et al. TOXICOLOGICAL SCIENCES
- Peripheral site ligand conjugation to a non-quaternary oxime enhances reactivation of nerve agent-inhibited human acetylcholinesterase
- (2011) Martijn C. de Koning et al. TOXICOLOGY LETTERS
- Subacute developmental exposure of zebrafish to the organophosphate pesticide metabolite, chlorpyrifos-oxon, results in defects in Rohon-Beard sensory neuron development
- (2010) Saskia M. Jacobson et al. AQUATIC TOXICOLOGY
- Development of a Prolonged Calcium Plateau in Hippocampal Neurons in Rats Surviving Status Epilepticus Induced by the Organophosphate Diisopropylfluorophosphate
- (2010) Laxmikant S. Deshpande et al. TOXICOLOGICAL SCIENCES
- Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo
- (2009) Edor Kabashi et al. HUMAN MOLECULAR GENETICS
- The possible use of oximes as antidotal therapy in organophosphate-induced brain damage
- (2008) Shai Shrot et al. NEUROTOXICOLOGY
- Zebrafish based assays for the assessment of cardiac, visual and gut function — potential safety screens for early drug discovery
- (2008) Stéphane Berghmans et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Efficacy of antidotal treatment against sarin poisoning: The superiority of benactyzine and caramiphen
- (2007) Lily Raveh et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation