Article
Biology
Hui Zhao, Jianping Zhao, Di Wu, Zhaolin Sun, Yang Hua, Min Zheng, Yumei Liu, Qi Yang, Xiahe Huang, Yuan Li, Yueshan Piao, Yingchun Wang, Sin Man Lam, Huijuan Xu, Guanghou Shui, Yongjun Wang, Haifeng Yao, Liangxue Lai, Zhuo Du, Jidong Mi, Enqi Liu, Xunming Ji, Yong Q. Zhang
Summary: This study demonstrates the generation of ApoE knockout dogs using CRISPR/Cas9 and somatic cell nuclear transfer technologies, which exhibit hypercholesterolemia and severe atherosclerosis with clinical manifestations. The characteristics of hypercholesterolemia and atherosclerosis in mutant dogs and their offspring make them valuable models for developing and evaluating new therapies against atherosclerosis and related disorders, as they closely resemble human patients more than other animal models.
SCIENCE CHINA-LIFE SCIENCES
(2022)
Article
Hematology
Marine Coue, Mikael Croyal, Marina Habib, Blandine Castellano, Audrey Aguesse, Isabelle Grit, Mathilde Gourdel, Helene Billard, Olivier Lepine, Catherine Michel, Khadija Ouguerram
Summary: This study found that perinatal administration of C-phycocyanin concentrate can reduce the risk of atherosclerosis in genetically hypercholesterolemic mice in adulthood, with a gender-specific protective effect. Supplementation of mothers with antioxidants can influence gallbladder bile acid pool, plasma trimethylamine N-oxide levels, and other related factors in the offspring.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2021)
Article
Biology
Anahita Garg, Jetty Chung-Yung Lee
Summary: This review examines the role of dietary vitamin E as an antioxidant and bioactive molecule in promoting vascular health. While the antioxidant effect of vitamin E is well established, its capacity as a promising regulatory molecule in the control of the vascular system needs further research. The article also discusses foods rich in vitamin E and potential toxicological effects of excessive supplemental vitamin E.
Article
Multidisciplinary Sciences
Ping Gao, Miao Ji, Xinyuan Liu, Xiaotong Chen, Hongtao Liu, Shihua Li, Baoqian Jia, Chao Li, Lili Ren, Xin Zhao, Qihui Wang, Yuhai Bi, Xu Tan, Baidong Hou, Xuyu Zhou, Wenjie Tan, Tao Deng, Jianwei Wang, George Fu Gao, Fuping Zhang
Summary: A study found that APOE affects influenza virus infection, with APOE deficiency making cells more susceptible to IAV infection and mice deficient in APOE showing more severe lung pathology and decreased survival rates.
Review
Fisheries
Abdel-Fattah M. El-Sayed, Marisol Izquierdo
Summary: Vitamin E plays a crucial role in farmed fish, providing antioxidant protection, improving immune response and growth performance, reducing muscle degeneration and atherosclerosis risk, enhancing reproductive efficiency and product quality. Consideration should be given to the interaction of VE with vitamin C and selenium, as well as lipid content in feed when supplementing VE.
REVIEWS IN AQUACULTURE
(2022)
Article
Education, Scientific Disciplines
Hongli Wang, Zhinan Zheng, Nanrong Zhang, Yan Zhou, Sanqing Jin
Summary: Regular transient limb ischemia (RTLI) has been shown to prevent atherosclerosis in hypercholesterolemic rabbits by improving endothelial function.
Review
Biology
Sarah Kolnik, Thomas R. Wood
Summary: Vitamin E has potential as a neuroprotectant in newborn infants with brain injury, but its effectiveness in clinical settings is still uncertain. Recent studies have shown that fat emulsions containing higher levels of Vitamin E can improve outcomes in neonatal co-morbidities, leading to a reconsideration of Vitamin E administration as a potential therapeutic modality. This review discusses the structure, mechanism(s) of action, evidence in animal models, and association with health outcomes in neonates, highlighting the need for further research and assessment of safety profiles before large clinical trials.
Article
Chemistry, Applied
Mengjie Geng, Xumei Feng, Xixi Wu, Xiangyun Tan, Zengnan Liu, Lijia Li, Yuyang Huang, Fei Teng, Yang Li
Summary: A core-shell structure based on soy protein isolate (SPI) and pectin was constructed as a delivery system for vitamins C and E. The SPI-vitamin-pectin complex formed at pH 4.0 showed better encapsulation efficiency and larger particle size compared to that formed at pH 7.0. Additionally, the addition of vitamin C enhanced the encapsulation efficiency of vitamin E and increased the antioxidant properties of the system.
Article
Biochemistry & Molecular Biology
Priscila Faimann Sales, Aline Lopes do Nascimento, Fernanda Cavalcante Pinheiro, Andressa Ketelem Meireles Alberto, Abrahao Victor Tavares de Lima Teixeira dos Santos, Helison de Oliveira Carvalho, Gisele Custodio de Souza, Jose Carlos Tavares Carvalho
Summary: This study found that oils from A. esculentus, E. oleracea, B.orellana, and Chronic SM (R) have therapeutic effects on dyslipidemia, reducing blood sugar, triglycerides, total cholesterol, and LDL-cholesterol, while increasing HDL-cholesterol. Additionally, they were able to inhibit the formation of atheromatous plaques in the vascular endothelium of treated rats.
Article
Hematology
Esmeralda A. Lewis, Rocio Muniz-Anquela, Ibon Redondo-Angulo, Leticia Gonzalez-Cintado, Veronica Labrador-Cantarero, Jacob F. Bentzon
Summary: This study found that LDL retention is the main limiting factor for LDL accumulation in the arterial wall. However, the capacity for LDL retention varies significantly over relatively short distances. The inner curvature region of the aortic arch consists of dorsal and ventral zones with high retention capacity and a central zone with low retention capacity. These features predict the temporal pattern of atherosclerosis.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Alejandro Jurado-Campos, Pedro Javier Soria-Meneses, Francisca Sanchez-Rubio, Enrique Niza, Ivan Bravo, Carlos Alonso-Moreno, Maria Arenas-Moreira, Olga Garcia-alvarez, Ana Josefa Soler, Jose Julian Garde, Maria del Rocio Fernandez-Santos
Summary: The use of hydrogel and nanoemulsion carriers for vitamin E showed promising results in preventing oxidative stress in sperm cells, maintaining sperm viability and kinematic parameters. This new formulation of vitamin E could be a significant approach for preserving sperm physiology and protecting against oxidative damage.
Review
Medicine, General & Internal
Fahad Alnouri, Raul D. Santos
Summary: Familial hypercholesterolemia (FH) is associated with an increased risk of atherosclerosis. In heterozygous FH, cardiovascular risk is not only determined by high cholesterol levels but also by other biomarkers and genes. Specific atherosclerosis risk scores for FH and imaging of subclinical coronary atherosclerosis can help identify high-risk individuals.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Immunology
Mohammad-Hossein Shams, Reza Jafari, Nahid Eskandari, Mohsen Masjedi, Farnaz Kheirandish, Mazdak Ganjalikhani Hakemi, Ramin Ghasemi, Ali-Mohammad Varzi, Seyyed-Mohsen Sohrabi, Peyman Amanolahi Baharvand, Mozhgan Safari
Summary: Allergic diseases have significantly increased globally in recent decades, influenced by genetic factors, industrialization, improved hygiene, and climate change. Changes in lifestyle and diet habits also play a key role in the prevalence of allergic diseases.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Giulia Ciarcia, Simone Bianchi, Barbara Tomasello, Rosaria Acquaviva, Giuseppe Antonio Malfa, Irina Naletova, Alfonsina La Mantia, Claudia Di Giacomo
Summary: Vitamin E has antioxidant and anti-inflammatory activities, and acts as an immunomodulator. However, studies on its ability to prevent and control chronic diseases have yielded conflicting results. The metabolism of vitamin E and its interaction with gut microbiota may contribute to these divergent findings. Additionally, vitamin E serum levels, dietary intake, and/or supplementation are correlated with various non-communicable diseases.
Article
Nutrition & Dietetics
Yongjae Kim, Sungjae Shin, Namki Hong, Yumie Rhee
Summary: This study found that lower serum vitamin E levels were associated with decreased hand grip strength in older men living in the community, but not in women. Individuals with the lowest vitamin E levels had higher odds of low hand grip strength, independent of various other factors. Further validation of these findings is needed.
Article
Surgery
Akgun Oral, Leyla Karaca, Ali Ahiskalioglu, Abdullah Yildiz, Murat Yigiter, Mehmet Emin Celikkaya, Temirlan Chyndolotov, Ahmet Bedii Salman
JOURNAL OF INVESTIGATIVE SURGERY
(2019)
Article
Surgery
Mohammed Abdallah Salman, Doaa Ahmed Mansour, Hany Armia Balamoun, Mohamed Yehia Elbarmelgi, Kareem Essam Eldin Hadad, Mohammad Elsherbiny Abo Taleb, Ahmed Salman
ASIAN JOURNAL OF SURGERY
(2019)
Article
Thermodynamics
Irfan Anjum Badruddin, N. J. Salman Ahmed, Ali E. Anqi, Sarfaraz Kamangar
JOURNAL OF THERMOPHYSICS AND HEAT TRANSFER
(2019)
Article
Chemistry, Multidisciplinary
Ibrahim F. Zeid, Neama A. Mohamed, Nagy M. Khalifa, Emad M. Kassem, Eman S. Nossier, Ahmed A. Salman, Khaled Mahmoud, Mohamed A. Al-Omar
JOURNAL OF CHEMISTRY
(2019)
Review
Surgery
Mohamed Abdallah Salman, Ahmed Abdallah Salman, Ahmed Hamdy, Rasha M. Abdel Samie, Mohammed Ewid, Tarek Elsayed Abouregal, Sayed M. Seif El Nasr, Hesham Elkassar, Ahmed Abdallah, Mohamed Yousef, Amro Abdelaziz Mohammed Ismail, Ayman Alsebaey, Mohamed Matter
ASIAN JOURNAL OF SURGERY
(2020)
Article
Immunology
Catherin Marin-Mogollon, Ahmed M. Salman, Karin M. J. Koolen, Judith M. Bolscher, Fiona J. A. van Pul, Shinya Miyazaki, Takashi Imai, Ahmad Syibli Othman, Jai Ramesar, Geert-Jan van Gemert, Hans Kroeze, Severine Chevalley-Maurel, Blandine Franke-Fayard, Robert W. Sauerwein, Adrian V. S. Hill, Koen J. Dechering, Chris J. Janse, Shahid M. Khan
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2019)
Article
Computer Science, Artificial Intelligence
Ebrahim Eslami, Ahmed Khan Salman, Yunsoo Choi, Alqamah Sayeed, Yannic Lops
NEURAL COMPUTING & APPLICATIONS
(2020)
Article
Surgery
Mohamed Abdalla Salman, Ahmed Abdallah Salman, Ahmed Abdelsalam, Mohamed Atallah, Hossam El-Din Shaaban, Ahmed El-Mikkawy, Mahmoud Gouda Omar, Mai Elshenoufy
Article
Medicine, General & Internal
Mohammed A. Nafea, Ayman Alsebaey, Ahmed Abd El Aal Sultan, Mohammed Hisham Goda, Ahmed Salman, Hanaa Said Rashed, Ahmed Soliman, Mai Elshenoufy, Mostafa Abdelrahman
ANNALS OF SAUDI MEDICINE
(2019)
Article
Immunology
Benedict R. Halbroth, Sarah Sebastian, Ahmed M. Salman, Marta Ulaszewska, Anita Gola, Rhea J. Longley, Chris J. Janse, Shahid M. Khan, Adrian V. S. Hill, Alexandra J. Spencer
INFECTION AND IMMUNITY
(2020)
Article
Surgery
Mohamed Abdalla Salman, Mohamed El-ghobary, Ahmed Soliman, Mohammad El Sherbiny, Tarek Elsayed Abouelregal, Amr Albitar, Ahmed Abdallah, Hani Maurice Sabri Mikhail, Mohammed A. Nafea, Ahmed Abd El Aal Sultan, Hossam E. Elshafey, Hossam El-Din Shaaban, Ayman Azzam, Ghada M. K. GabAllah, Ahmed Abdallah Salman
Article
Surgery
Mohamed A. Salman, Haitham S. E. Omar, Hani M. S. Mikhail, Mohamed Tourky, Mohamed El-ghobary, Hesham Elkassar, Mahmoud G. Omar, Mohamed Matter, Ahmed M. Elbasiouny, Ayman M. Farag, Hossam El-Din Shaaban, Mohamed Atallah, Omar Elshabacy, Ahmed A. Salman
ANZ JOURNAL OF SURGERY
(2020)
Article
Veterinary Sciences
Ahmed Salman, Maha El Beltagy, Amjad Shatarat, Loai Alzghoul, Liyana Oweis, Nada Al Antary, Safa Al Fegie, Maram Mohsen, Salma Salman
VETERINARY MEDICINE AND SCIENCE
(2020)
Article
Anatomy & Morphology
Ahmed Salman, Dalia El-Sayed El-Ghazouly, Maha El-Beltagy
INTERNATIONAL JOURNAL OF MORPHOLOGY
(2020)