Evaluation of relative effect potencies (REPs) for dioxin-like compounds to derive systemic or human-specific TEFs to improve human risk assessment

Consensus Toxicity Factors for Polychlorinated Dibenzo-p-dioxins, Dibenzofurans, and Biphenyls Combining in Silico Models and Extensive in Vitro Screening of AhR-Mediated Effects in Human and Rodent Cells

(2015) Malin Larsson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Differential relative effect potencies of some dioxin-like compounds in human peripheral blood lymphocytes and murine splenic cells

(2014) Karin I. van Ede et al.   TOXICOLOGY LETTERS

Comparison of intake and systemic relative effect potencies of dioxin-like compounds in female rats after a single oral dose

(2013) Karin I. van Ede et al.   ARCHIVES OF TOXICOLOGY

Toxicokinetics of dioxins and other organochlorine compounds in Japanese people: Association with hepatic CYP1A2 expression levels

(2013) Michio X. Watanabe et al.   ENVIRONMENT INTERNATIONAL

Comparison of Intake and Systemic Relative Effect Potencies of Dioxin-like Compounds in Female Mice after a Single Oral Dose

(2013) Karin I. van Ede et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

PCDD/F and PCB concentrations in sera from the Canadian Health Measures Survey (CHMS) from 2007 to 2009

(2012) Dorothea F.K. Rawn et al.   ENVIRONMENT INTERNATIONAL

Evaluation of Biomonitoring Data from the CDC National Exposure Report in a Risk Assessment Context: Perspectives across Chemicals

(2012) Lesa L. Aylward et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Mechanism-based common reactivity pattern (COREPA) modelling of aryl hydrocarbon receptor binding affinity

(2010) P.I. Petkov et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Analysis of the CYP1A1 mRNA Dose-Response in Human Keratinocytes Indicates that Relative Potencies of Dioxins, Furans, and PCBs Are Species and Congener Specific

(2010) Carrie H. Sutter et al.   TOXICOLOGICAL SCIENCES

Human and Rat Primary Hepatocyte CYP1A1 and 1A2 Induction with 2,3,7,8-Tetrachlorodibenzo-p-dioxin, 2,3,7,8-Tetrachlorodibenzofuran, and 2,3,4,7,8-Pentachlorodibenzofuran

(2010) Robert A. Budinsky et al.   TOXICOLOGICAL SCIENCES

Divergent Transcriptomic Responses to Aryl Hydrocarbon Receptor Agonists between Rat and Human Primary Hepatocytes

(2009) Erik A. Carlson et al.   TOXICOLOGICAL SCIENCES

Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition

(2008) Walter M. A. Westerink et al.   ARCHIVES OF TOXICOLOGY

Derivation of Biomonitoring Equivalent (BE) Values for 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) and Related Compounds: A Screening Tool for Interpretation of Biomonitoring Data in a Risk Assessment Context

(2008) Lesa L. Aylward et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES