Article
Chemistry, Analytical
Min Gyu Joo, Dae Hyeong Lim, Kyu-Kwan Park, Jiwon Baek, Jong Min Choi, Hyoung Won Baac
Summary: In this study, a Monte Carlo simulation was used to model a finger structure and calculate the intensity of photons passing through tissues for SpO(2) detection. A mirror-coated ring-type pulse oximeter (RPO) was proposed to improve sensitivity and power consumption compared to the mirror-uncoated structure. The simulation allowed the numerical calculation of photon intensity, and the reflection-boosted RPO design greatly enhanced light intensity and perfusion index while reducing power consumption.
Article
Chemistry, Analytical
Zhongxing Zhang, Ming Qi, Gordana Huegli, Ramin Khatami
Summary: Obstructive sleep apnea (OSA) is a common sleep disorder, and continuous positive airway pressure (CPAP) is the most effective treatment. However, poor adherence to CPAP therapy is a major challenge. The recent development of wearable optical sensors has made it possible to conduct at-home CPAP titrations over multiple nights, potentially improving therapy adherence. In this study, we found that the arm oxygen desaturations (ODs), measured by gold-standard frequency-domain multi-distance near-infrared spectroscopy (FDMD-NIRS), did not quantitatively change with titrated CPAP pressures in OSA patients. This suggests that arm OD measured by optical sensors may not be a suitable indicator of CPAP titration effectiveness.
Article
Chemistry, Analytical
Lenka Horakova, Karel Roubik
Summary: The reliability of pulse oximetry during rapid changes in body oxygenation is questionable, as it often yields inconsistent results. Therefore, it may not be suitable as a study endpoint or a safety limit in outdoor experiments. Future studies should consider incorporating more parameters and continuous clinical assessment.
Article
Computer Science, Information Systems
Juanning Si, Xin Zhang, Meng Li, Jian Yu, Zhiyong Zhang, Qing He, Shaohua Chen, Lianqing Zhu, Tianzi Jiang
Summary: Monitoring regional cerebral oxygen saturation is crucial for successful patient outcomes in perioperative care, but current devices are limited to bedside use. A newly designed head-mounted WORTH band provides wearable, wireless monitoring of oxygen saturation during motion tasks, showing accuracy comparable to clinical monitors.
SCIENCE CHINA-INFORMATION SCIENCES
(2021)
Article
Endocrinology & Metabolism
Ricardo L. M. Duarte, Flavio J. Magalhaes-da-Silveira, David Gozal
Summary: Nighttime oximetry data is significantly correlated with AHI, with ODI being the best parameter for predicting OSA severity levels. ODI is a valid surrogate predictor of AHI and shows improved performance in identifying high-risk individuals for OSA compared to low-risk individuals.
Article
Health Care Sciences & Services
Romain Kirszenblat, Paul Edouard
Summary: The study aimed to test and validate the accuracy of the reflective pulse oximeter function of Withings ScanWatch in measuring SpO(2) levels at different stages of hypoxia, as well as to confirm its safety when used as intended.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Clinical Neurology
Tuomas Karhu, Timo Leppanen, Henri Korkalainen, Sami Myllymaa, Brett Duce, Juha Toyras, Sami Nikkonen
Summary: The severity of hypoxic load is greatly affected by different desaturation scoring criteria, but the difference in the prediction of impaired vigilance is relatively small.
Article
Obstetrics & Gynecology
Micaela Thomas, Heather Day, Brandy Petersen, Trisha Marchant, Cory Jones, Yogen Singh, Belinda Chan
Summary: This study compared the accuracy of wireless Owlet Smart Sock 3 (OSS3) and wired Masimo SET pulse oximeter in monitoring heart rate (HR) and oxygen saturation (SpO(2)) in preterm or <2.5 kg infants. The results showed that OSS3 provided comparable accuracy to Masimo in HR and SpO(2) in these infants.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Article
Respiratory System
Asuka Yoshizaki, Tatsuya Nagano, Shintaro Izumi, Teruaki Nishiuma, Kyosuke Nakata, Masatsugu Yamamoto, Yuichiro Yasuda, Daisuke Hazama, Kanoko Umezawa, Naoko Katsurada, Motoko Tachihara, Yoshihiro Nishimura, Kazuyuki Kobayashi
Summary: In this study, it was found that nocturnal desaturation is common among patients with COPD and can be classified into 3 waveform patterns. The intermittent pattern was associated with the apnoea-hypopnea index, while the sustained pattern was associated with the cumulative percentage of time with SpO(2) below 90%.
RESPIRATORY RESEARCH
(2021)
Article
Multidisciplinary Sciences
Catarina Duarte Santos, Ana Filipe Santos, Rui Cesar das Neves, Ruy M. Ribeiro, Fatima Rodrigues, Catia Caneiras, Martijn A. Spruit, Cristina Barbara
Summary: This study compared the accuracy of the six-minute walk test and daily-life telemonitoring in identifying patients who desaturate during physical activities, finding that telemonitoring was more effective in detecting these patients. The results suggest that telemonitoring may be a better tool for assessing oxygen desaturation during exercise and guiding interventions in pulmonary rehabilitation.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Analytical
Mukul Sarkar, Maher Assaad
Summary: This research proposes a reflexive mode polarized imaging-based iPPG method, which can monitor changes in heart rate and blood oxygen saturation in real time. The quantitative analysis of reflective information from superficial and deep layers of skin is achieved using phase information, providing real-time results of heart rate and SpO(2). This method has the advantages of non-contact, compactness, and portability.
Article
Chemistry, Analytical
Emilio Andreozzi, Riccardo Sabbadini, Jessica Centracchio, Paolo Bifulco, Andrea Irace, Giovanni Breglio, Michele Riccio
Summary: This study presents a true multimodal pulse wave (PW) sensor that integrates a piezoelectric forcecardiography (FCG) sensor and a photoplethysmography (PPG) sensor for simultaneous mechanical-optical measurements of PWs from the same body site. The preliminary results show a delay between the PWs recorded by the PPG and FCG sensors, but high cross-correlation indices were observed. Further investigation is needed to understand the physical origin of the delay and validate the results in a larger subject cohort. This research paves the way for the development of wearable, integrated sensors and sensor fusion approaches to improve PW monitoring.
Article
Pediatrics
Jesus Rodriguez-Lopez, Javier de la Cruz Bertolo, Nadia Raquel Garcia-Lara, Jose Luis Nunez Vecino, Maria Soriano-Ramos, Izaskun Asla Elorriaga, Lourdes Roman Echevarria, Adelina Pellicer, Natalia Marin Huarte, Maximo Vento, Anna Parra-Llorca, Fernando Cabanas, Raquel Gonzalez Sanchez, Oscar Garcia-Algar, Ana Martin-Ancel, Cristina Copons Fernandez, Ersilia Gonzalez Carrasco, Maite Beato, Carmen Rosa Pallas-Alonso
Summary: The study evaluated the impact of mother's bed incline during ESSC on desaturation episodes in healthy term newborns (HTNs). Results showed that a higher bed inclination did not significantly reduce the occurrence of SpO2 <91% episodes in HTNs, with over half of the newborns experiencing desaturation within 10 minutes to 2 hours after birth.
Article
Health Care Sciences & Services
Mauro Santos, Sarah Vollam, Marco Af Pimentel, Carlos Areia, Louise Young, Cristian Roman, Jody Ede, Philippa Piper, Elizabeth King, Mirae Harford, Akshay Shah, Owen Gustafson, Lionel Tarassenko, Peter Watkinson
Summary: Wearable finger-worn pulse oximeters can detect the onset of clinical deterioration in hospital settings, although their performance is affected by motion, they are still able to detect hypoxemia.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Health Care Sciences & Services
Andrea Torres-Robles, Karen Allison, Simon K. Poon, Miranda Shaw, Owen Hutchings, Warwick J. Britton, Andrew Wilson, Melissa Baysari
Summary: This study explores the use, performance, and acceptability of a pulse oximeter for remote monitoring during COVID-19. The results show that both patients and clinicians had positive perceptions of the device, considering it highly acceptable and easy to use. However, some factors such as patient age and device-related characteristics may negatively impact its accuracy.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Letter
Toxicology
P. Marx-Stoelting, G. Riviere, M. Luijten, K. Aiello-Holden, N. Bandow, K. Baken, A. Canas, A. Castano, S. Denys, C. Fillol, M. Herzler, I. Iavicoli, S. Karakitsios, J. Klanova, M. Kolossa-Gehring, A. Koutsodimou, J. Lobo Vicente, I. Lynch, S. Namorado, S. Norager, A. Pittman, S. Rotter, D. Sarigiannis, M. J. Silva, J. Theunis, T. Tralau, M. Uhl, J. van Klaveren, L. Wendt-Rasch, E. Westerholm, C. Rousselle, P. Sanders
Summary: Current approaches for chemical risk assessment are facing challenges due to the increasing number and changing types of chemicals. Next-generation risk assessment is seen as the way forward, but incorporating new scientific insights and innovative approaches is challenging. The European Partnership for the Assessment of Risks from Chemicals (PARC) aims to address these challenges and consolidate Europe's research and innovation capacity in chemical risk assessment.
ARCHIVES OF TOXICOLOGY
(2023)
Article
Biology
Peter Broede, Jean-Marie Aerts, Guido De Bruyne, Tiago Sotto Mayor, Simon Annaheim, Dusan Fiala, Kalev Kuklane
Summary: A modeling framework is proposed for assessing the thermal comfort of bicycle helmet use based on human head sweating and helmet thermal properties. The framework incorporates local sweat rates, thermoregulation models, and regression equations for wind-related reductions in thermal insulation. Results show a large spread in sweat rate predictions, with some models performing better for specific head regions.
JOURNAL OF THERMAL BIOLOGY
(2023)
Article
Respiratory System
Francis-Edouard Gravier, Joren Buekers, Pauline Smondack, Fairuz Boujibar, Guillaume Prieur, Clement Medrinal, Yann Combret, Jean-Francois Muir, Jean-Marc Baste, Antoine Cuvelier, David Debeaumont, Tristan Bonnevie
Summary: This study aimed to explore the feasibility of using oxygen uptake and heart rate as measures to evaluate the response to a prehabilitation program in patients with non-small cell lung cancer (NSCLC). The results showed that after a 15-session prehabilitation program, there were improvements in oxygen uptake and heart rate during exercise. These results support the concept of a faster adaptation of aerobic metabolism through prehabilitation training.
Article
Chemistry, Analytical
Inti Vanmechelen, Saranda Bekteshi, Helga Haberfehlner, Hilde Feys, Kaat Desloovere, Jean-Marie Aerts, Elegast Monbaliu
Summary: This study evaluated the reliability and discriminative ability of sensor parameters in individuals with Dyskinetic cerebral palsy (DCP). The results showed that most sensor parameters have good reliability and discriminative ability, and can reliably capture the pathological movements of individuals with DCP.
Article
Chemistry, Multidisciplinary
Alberto Pena Fernandez, Cato Leenders, Jean-Marie Aerts, Daniel Berckmans
Summary: This technology aims to monitor emotions in real-time using the mental heart rate component. It allows mental health experts to provide advice based on objective data, enabling early detection and prevention of mental disease. This research investigates the possibilities of using mental heart rate component to classify discrete emotions.
APPLIED SCIENCES-BASEL
(2023)
Review
Respiratory System
Anouk W. Vaes, Patrick De Boever, Frits M. E. Franssen, Nicole H. M. K. Uszko-Lencer, Lowie E. G. W. Vanfleteren, Martijn A. Spruit
Summary: This article summarizes the current knowledge on endothelial function in COPD patients, indicating that COPD patients have impaired endothelial function, and higher age, worse severity of airflow obstruction, and current smoking are significantly associated with impaired endothelial function.
EXPERT REVIEW OF RESPIRATORY MEDICINE
(2023)
Article
Engineering, Chemical
Kathleen Van Beylen, Janne Reynders, Ahmed Youssef, Alberto Pena Fernandez, Ioannis Papantoniou, Jean-Marie Aerts
Summary: Providing a cost-efficient feeding strategy for cell expansion processes is challenging due to donor variability. A model predictive controller was developed to take into account the individual needs of the cells, using reference experiments and a time-variant prediction model. Multiple forecast methods were employed to predict cell growth, and the second controller experiment successfully avoided over- or underfeeding the cells by using a time-adaptive target function.
Article
Medicine, Research & Experimental
Anouk W. Vaes, Maarten Van Herck, Qichen Deng, Jeannet M. Delbressine, Leonard A. Jason, Martijn A. Spruit
Summary: This study aimed to identify symptom-based clusters in ME/CFS patients based on the frequency and severity of symptoms. The results showed that ME/CFS patients can be categorized into different symptom clusters with distinct patterns, providing insights for tailored treatment options.
JOURNAL OF TRANSLATIONAL MEDICINE
(2023)
Article
Allergy
Joren Buekers, Michiel Stas, Raf Aerts, Nicolas Bruffaerts, Sebastien Dujardin, An Van Nieuwenhuyse, Jos Van Orshoven, Guillaume Chevance, Ben Somers, Jean-Marie Aerts, Judith Garcia-Aymerich
Summary: This study aimed to estimate the associations between daily allergy burden and heart rate characteristics of adults with allergic rhinitis. The results showed that an increase in allergy symptom score was associated with an increase in next-day resting heart rate, and an increase in mood score was associated with an increase in same-day sample entropy. These findings suggest that daily allergy burden has systemic effects beyond the respiratory system.
CLINICAL AND TRANSLATIONAL ALLERGY
(2023)
Article
Medicine, General & Internal
Adam Salon, Bianca Steuber, Ruslan Neshev, Karin Schmid-Zalaudek, Patrick De Boever, Eva Bergmann, Rainer Picha, Per Morten Fredriksen, Benedicta Ngwechi Nkeh-Chungag, Nandu Goswami
Summary: This pilot study aimed to assess the effect of Maharishi light therapy (MLT) on physiological parameters in healthy participants. The study found significant changes in retinal parameters, but the baseline measurements already showed large biological variation, suggesting that the observed effects may be due to natural fluctuations in microcirculation rather than MLT. Larger studies in different patient populations may reveal the physiological impacts of this therapy.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Freya Peeters, Stef Rommes, Bart Elen, Nele Gerrits, Ingeborg Stalmans, Julie Jacob, Patrick De Boever
Summary: The MONA.health artificial intelligence screening software showed good performance in detecting referable diabetic retinopathy (DR) and diabetic macular edema (DME). The software achieved high sensitivity and specificity on both private test set and publicly available datasets. Subgroup analysis revealed slightly lower predictive values for individuals above the age of 65 and Caucasians.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Respiratory System
J. M. Delbressine, D. Jensen, A. W. Vaes, P. Z. Li, J. Bourbeau, W. C. Tan, B. Hajian, A. J. van 't Hul, M. A. Spruit
Summary: This study established reference equations for 6MWD and 6MWORK on a 20 m course in Caucasian males and females aged 40 years and older with normal pulmonary function, self-reported health status, and exercise capacity, providing added value for the assessment of functional capacity in clinical practice.
Article
Environmental Sciences
Brigitte Reimann, Hanne Sleurs, Yinthe Dockx, Leen Rasking, Patrick De Boever, Catherine Pirard, Corinne Charlier, Tim S. Nawrot, Michelle Plusquin
Summary: This study investigated the association between paraben exposure and cardiometabolic indicators and obesity in preschool children. The results showed that exposure to methylparaben and propylparaben was related to abnormal retinal microvasculature, while exposure to ethylparaben was negatively associated with obesity and blood pressure. These findings suggest that early exposure to parabens may have important implications for cardiometabolic health later in life.
Article
Respiratory System
Joren Buekers, Dimitrios Megaritis, Sarah Koch, Lisa Alcock, Nadir Ammour, Clemens Becker, Stefano Bertuletti, Tecla Bonci, Philip Brown, Ellen Buckley, Sara C. Buttery, Brian Caulfied, Andrea Cereatti, Nikolaos Chynkiamis, Heleen Demeyer, Carlos Echevarria, Anja Frei, Clint Hansen, Jeffrey M. Hausdorff, Nicholas S. Hopkinson, Emily Hume, Arne Kuederle, Walter Maetzler, Claudia Mazza, Encarna M. Mico-Amigo, Arne Mueller, Luca Palmerini, Francesca Salis, Kirsty Scott, Thierry Troosters, Beatrix Vereijken, Henrik Watz, Lynn Rochester, Silvia Del Din, Ioannis Vogiatzis, Judith Garcia-Aymerich
Summary: Gait impairment in adults with mild-to-severe COPD mainly manifests during longer free-living walking bouts (>30 s). Walking speed and cadence are significantly slower in COPD adults compared to healthy controls during longer free-living walking bouts, but not during shorter walking bouts. Double support duration and gait variability measures are generally comparable between the two groups.
Article
Toxicology
Maryam Zare Jeddi, Karen S. Galea, Susana Viegas, Peter Fantke, Henriqueta Louro, Jan Theunis, Eva Govarts, Sebastien Denys, Clemence Fillol, Loic Rambaud, Marike Kolossa-Gehring, Tiina Santonen, Hilko van der Voet, Manosij Ghosh, Carla Costa, Joao Paulo Teixeira, Hans Verhagen, Radu-Corneliu Duca, An Van Nieuwenhuyse, Kate Jones, Craig Sams, Ovnair Sepai, Giovanna Tranfo, Martine Bakker, Nicole Palmen, Jacob van Klaveren, Paul T. J. Scheepers, Alicia Paini, Cristina Canova, Natalie von Goetz, Andromachi Katsonouri, Spyros Karakitsios, Dimosthenis A. Sarigiannis, Jos Bessems, Kyriaki Machera, Stuart Harrad, Nancy B. Hopf
Summary: The impact of the environment on health is a necessary result of human activity. Environmental health sciences aim to understand how people are exposed to hazardous chemicals that can harm their health. Implementing the FAIR principles for scientific data management can greatly enhance the efficiency and effectiveness of exposure sciences and environmental epidemiology.
FRONTIERS IN TOXICOLOGY
(2023)