Article
Public, Environmental & Occupational Health
Brooke G. Rogers, P. A. Chan, C. Sutten-Coats, A. Zanowick-Marr, R. R. Patel, L. Mena, W. C. Goedel, C. Chu, E. Silva, D. Galipeau, T. Arnold, C. Gomillia, K. Curoe, J. Villalobos, A. Underwood, C. Sosnowy, Amy S. Nunn
Summary: This study examined the perspectives of 49 men who have sex with men (MSM) on long-acting formulations of PrEP. The findings suggest that although participants were not very knowledgeable about long-acting PrEP, they were open to learning about and considering these options. Safety, efficacy, and reducing clinic visits were identified as important factors in their decision-making process.
Article
Immunology
Christina Chandra, Kevin M. Weiss, Colleen F. Kelley, Julia L. Marcus, Samuel M. Jenness
Summary: The study found substantial gaps between CDC recommendations for STI screening during PrEP care and current clinical practice, particularly for MSM in the Southeast states, where screening for urogenital and rectal STIs was significantly less likely to be consistent compared to other regions.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Multidisciplinary Sciences
Francesc Lopez Segui, Unai Oyon Lerga, Laura Laguna Marmol, Pep Coll, Angels Andreu, Michael Meulbroek, Guillem Lopez Casasnovas, Oriol Estrada Cuxart, Jordi Ara Rey, Carles Quinones, Felix Perez, Javier Fernandez, Angel Rivero, Laura Ricou Rios, Bonaventura Clotet
Summary: The study evaluates the cost-effectiveness of implementing HIV pre-exposure prophylaxis in Catalonia. The results show that daily oral PrEP can save costs and generate health and monetary benefits in the long term.
Article
Multidisciplinary Sciences
Oskar Ayerdi Aguirrebengoa, Mar Vera Garcia, Daniel Arias Ramirez, Natalia Gil Garcia, Teresa Puerta Lopez, Petunia Clavo Escribano, Juan Ballesteros Martin, Clara Lejarraga Canas, Nuria Fernandez Pineiro, Manuel Enrique Fuentes Ferrer, Monica Garcia Lotero, Estefania Hurtado Gallegos, Montserrat Raposo Utrilla, Vicente Estrada Perez, Jorge Del Romero Guerrero, Carmen Rodriguez Martin
Summary: The study observed risk compensation with a decrease in condom use rate after the introduction of PrEP, while the number of sexual partners and recreational drug consumption remained stable. Particularly among individuals under 30 years old with over 10 sexual partners per month, the incidence of STIs was higher.
Article
Gastroenterology & Hepatology
Daisuke Mizushima, Misao Takano, Takahiro Aoki, Naokatsu Ando, Haruka Uemura, Yasuaki Yanagawa, Koji Watanabe, Hiroyuki Gatanaga, Yoshimi Kikuchi, Shinichi Oka
Summary: The study evaluated the incidence of HBV infection among MSM and the effectiveness of tenofovir-based PrEP in preventing HBV infection. The results showed that the use of PrEP significantly reduced the rate of HBV infection among MSM, but individuals using PrEP were more susceptible to other sexually transmitted infections. A separate study on MSM with HBsAb-positive and HBcAb-negative status found an HBV incidence rate of 1.8% among PrEP users. In conclusion, tenofovir-based PrEP is effective in preventing HBV infection among MSM.
Article
Immunology
Vita W. Jongen, Thijs Reyniers, Zorah M. H. Ypma, Maarten F. Schim van der Loeff, Udi Davidovich, Hanne M. L. Zimmermann, Liza Coyer, Mark A. M. Elshout, Henry J. C. Vries, Kristien Wouters, Tom Smekens, Bea Vuylsteke, Maria Prins, Marie Laga, Elske Hoornenborg
Summary: The study found that a quarter of participants chose event-driven PrEP at baseline, and this proportion remained similar at 28 months. While the incidence rates of HCV and syphilis were similar in both regimens, the lower incidence of chlamydia and gonorrhoea among edPrEP users may suggest that less frequent STI testing of this group could be considered.
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY
(2021)
Article
Public, Environmental & Occupational Health
Inga Haaland, Emmy Metta, Kare Moen
Summary: Based on ethnographic fieldwork among men who have sex with men and transgender women in Tanzania, this article explores the various types of work that may go into enrolment into PrEP programming and using pre-exposure prophylaxis (PrEP). The study found that enrolling in PrEP programming and adhering to PrEP involved a wide range of tasks, which we conceptualize as work. This paper identifies and describes these tasks, categorizing them as readying work, user work, and social navigation work, collectively referred to as biomedical prevention work, and suggests that this framework can be applicable to other biomedical prevention methods in different contexts.
SOCIAL SCIENCE & MEDICINE
(2023)
Article
Immunology
Lauren E. Parmley, Tiffany G. Harris, Innocent Chingombe, Munyaradzi Mapingure, Owen Mugurungi, John H. Rogers, Perpetua Gozhora, Yingfeng Wu, Chesterfield Samba, Godfrey Musuka, Avi J. Hakim
Summary: The study assessed gaps in PrEP awareness, uptake, and use among MSM, TGW, and GQ individuals in Zimbabwe and highlighted the need for tailored interventions to promote PrEP among key populations.
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY
(2022)
Article
Public, Environmental & Occupational Health
Yuanqi Mi, Yuhong Zeng, Peicheng Wang, Mengge Zhou, Feng Cheng
Summary: This review assessed the cost-effectiveness of pre-exposure prophylaxis implementation among men who have sex with men in China. The findings suggest that pre-exposure prophylaxis is only cost-effective when the market price is reduced by at least 5.5%. The study calls for more standardized and transparent modeling studies that consider the latest drug types and market prices.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Psychology, Clinical
Redd Driver, Aerielle M. Allen, Stephanie Finneran, Jessica L. Maksut, Lisa A. Eaton, Seth C. Kalichman
Summary: The study found that traditional masculinity and PrEP stigma impact interest in PrEP among Black men who have sex with men, with avoidance of femininity and conformity to heterosexual self-presentation being key factors, and PrEP stigma moderating these relationships in different ways. Interventions to increase PrEP engagement for this population should address traditional masculinity as a barrier.
JOURNAL OF HEALTH PSYCHOLOGY
(2021)
Article
Multidisciplinary Sciences
Ashwin Belludi, Allison M. McFall, Sunil Suhas Solomon, David D. Celentano, Shruti H. Mehta, A. K. Srikrishnan, M. Suresh Kumar, Suniti Solomon, Gregory M. Lucas
Summary: The study in India revealed low awareness but high willingness to use PrEP among PWID and MSM. Common reasons for unwillingness to use PrEP included perceived low risk of HIV infection, fear of being labeled as HIV-positive, and concerns about side effects. Key factors associated with increased willingness to use PrEP included sharing needles and hazardous alcohol use among PWID, and having a main male partner and injection drug use among MSM.
Article
Health Care Sciences & Services
Bing Lin, Jiaxiu Liu, Wei He, Haiying Pan, Yingjie Ma, Xiaoni Zhong
Summary: This study explores the effect of a reminder system based on the WeChat social media app on PrEP adherence in MSM. The results indicate that the reminder system is significantly effective in improving adherence in the early stage, motivating users and facilitating the development of healthy medicine-taking habits.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Multidisciplinary Sciences
Jiaqi Fu, Zhenwei Dai, Hao Wang, Mingyu Si, Xu Chen, Yijin Wu, Weijun Xiao, Yiman Huang, Fei Yu, Guodong Mi, Xiaoyou Su
Summary: This study explores the willingness to use long-acting injectable-pre-exposure prophylaxis (LAI-PrEP) among men who have sex with men (MSM) in China. The study found that MSM had high awareness but low uptake of PrEP. The results highlight the need for education programs focused on PrEP and healthy sexual behavior, and provide evidence for future LAI-PrEP use among the Chinese MSM population.
Article
Multidisciplinary Sciences
Ryan D. Assaf, Kelika A. Konda, Thiago S. Torres, E. Hamid Vega-Ramirez, Oliver A. Elorreaga, Dulce Diaz-Sosa, Steven D. Diaz, Cristina Pimenta, Rebeca Robles, Maria Elena Medina-Mora, Beatriz Grinsztejn, Carlos Caceres, Valdilea G. Veloso
Summary: This study evaluated the association between higher risk of HIV infection and PrEP awareness among MSM in Brazil, Mexico, and Peru. The results showed a weak association between higher risk for HIV and PrEP awareness in Brazil, while no significant association was observed in Mexico and Peru. Factors such as education level, income, daily use of geosocial networking applications, and substance use were associated with PrEP awareness.
Article
Multidisciplinary Sciences
Hasina Samji, Jia Hu, Michael Otterstatter, Mark Hull, Troy Grennan, David Moore, Mark Gilbert, Rob Higgins, Jason Wong
Summary: A study on gbMSM attendees of STI clinics found that those with preceding or concurrent rectal STI diagnoses or syphilis had higher rates of HIV seroconversion, indicating the importance of including specific STI diagnoses as an indication for PrEP.
Article
Medicine, Research & Experimental
Pablo K. Valente, Yumeng Wu, Yehuda Z. Cohen, Marina Caskey, Kathrine Meyers
Summary: Early integration of behavioral and social sciences research into clinical trials with broadly neutralizing antibodies can improve participant understanding and address concerns. Educational materials collaboratively developed by researchers and stakeholders can help to promote communication, engagement, and informed consent among trial participants. Future research should focus on evaluating the impact of educational materials on recruitment and retention of participants in clinical trials.
Article
Public, Environmental & Occupational Health
Kathrine Meyers, Yumeng Wu, Kee-Young Shin, Jianhua Hou, Qinghai Hu, Junyi Duan, Yao Li, Xiaoqing He
Summary: The study found that individuals with higher education, lower PrEP stigma, and higher perceived benefits of PrEP were more likely to uptake PrEP in a demonstration project in China. Those who engaged in more frequent sex, had higher PrEP adherence self-efficacy, believed in the superior efficacy of daily over on-demand PrEP, and had less desire for a PrEP method taken only when needed were more likely to choose the daily PrEP regimen.
AIDS PATIENT CARE AND STDS
(2021)
Article
Public, Environmental & Occupational Health
Devon M. Price, Zoe Unger, Yumeng Wu, Kathrine Meyers, Sarit A. Golub
Summary: Uptake and persistence on PrEP in the US have been limited, requiring addressing barriers such as insurance coverage, clinical protocols, and provider bias. To reduce stigma, multiple approaches are needed to normalize PrEP education and services and center patient experiences. Addressing disparities requires acknowledging the interconnectedness between stigma and structural barriers.
AIDS PATIENT CARE AND STDS
(2022)
Article
Medicine, General & Internal
Jiaqi Wei, Jianhua Hou, Tingting Mu, Jun Sun, Shuang Li, Hao Wu, Bin Su, Tong Zhang
Summary: This study examined the association between computerized cognitive training (CCT) programs and cognitive and daily function among people living with HIV. The results showed that after receiving CCT, function significantly improved in 6 out of 8 domains, including abstraction and executive function, attention and working memory, memory, motor skills, speed of information processing, and daily function. However, sensory and perceptual skills and verbal and language skills did not significantly improve after CCT.
Article
Multidisciplinary Sciences
Nadia Nguyen, Benjamin Lane, Sangwon Lee, Sharon Lipsky Gorman, Yumeng Wu, Alicia Li, Helen Lu, Noemie Elhadad, Michael Yin, Kathrine Meyers
Summary: This study assessed the acceptability and adherence to a daily at-home mobile-app connected rapid antigen testing regimen among employees of a media company in the US. The results showed that most participants had a high level of acceptance and adherence to the daily testing intervention. However, there are three implementation challenges that need to be addressed for frequent serial testing to have a positive public health impact, including guidance on adjusting testing frequencies, guidelines for storing and sharing test results, and prioritizing health equity and protecting vulnerable populations.
Article
Psychology, Multidisciplinary
Biru Chang, Jianhua Hou
Summary: The closed-off management of the university during COVID-19 may result in elevated psychological and behavioral issues among college students. This study used the stress-process model to explore the potential mechanisms and found that negative coping styles and roommate relationships are possible psychological mechanisms linking the perceived risk of COVID-19, psychological distress, and internet addiction.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Rong Fu, Jianhua Hou, Yuzhou Gu, Nancy Xiaonan Yu
Summary: This systematic review and meta-analysis compared couple-based prevention interventions against individual-level interventions in HIV prevention. The findings showed that couple-based interventions were more effective in promoting condom use and HIV testing. Factors such as education level, residing in low- and middle-income countries, and incorporating HIV counseling and testing in interventions were associated with higher odds of condom use. Methodological and theoretical heterogeneity factors were also identified, highlighting the need for further investigation.
Article
Public, Environmental & Occupational Health
Tracy Shicun Cui, Benjamin Lane, Yumeng Wu, Jing Ma, Rong Fu, Jianhua Hou, Siyan Meng, Lu Xie, Yuzhou Gu, Xiaojie Huang, Huang Zheng, Yanling Ma, Na He, Kathrine Meyers
Summary: This study examines the willingness to use PrEP for HIV prevention among GBMSM in China using structural equation modeling. The findings indicate that knowledge, attitudes, and subjective norms are significantly related to intention to use PrEP, while general beliefs about medicines have no significant impact. These findings suggest the importance of interventions targeting knowledge, positive attitudes, and social norms to promote PrEP uptake among sexually active GBMSM.
Article
Gerontology
Shuyuan Chen, Zhihui Cai, Jianhua Hou, Minjia Lang, Zhiwei Zheng, Xinyi Zhu, Juan Li
Summary: Mnemonic training has immediate and long-term effects on episodic memory and subjective memory in older adults, improving their memory function. Future studies should consider real-world outcomes and multiple follow-ups to determine the impact of memory training on everyday functioning.
PSYCHOLOGY AND AGING
(2022)
Article
Public, Environmental & Occupational Health
Taiyi Jiang, Hou Jianhua, Jiaqi Wei, Tingting Mu, Guanlin Zhu, Xiuwen Wang, Diyang Qu, Hao Wu, Tong Zhang, Bin Su
Summary: This study examines the relationship between HIV-related stigma and sleep quality among people living with HIV (PLWH), and finds that HIV-related stigma may worsen sleep quality through increased depressive symptoms and feelings of loneliness. Additionally, social support is found to moderate the negative effects of HIV-related stigma on sleep quality. These findings highlight the importance of social support in reducing the impact of HIV-related stigma on sleep quality among PLWH.
TRANSLATIONAL BEHAVIORAL MEDICINE
(2023)
Article
Psychology, Multidisciplinary
Jianhua Hou, Rong Fu, Taiyi Jiang, Nancy Xiaonan Yu
Summary: This study examined the mediating role of common dyadic coping (CDC) in linking we-disease appraisal with relationship satisfaction and quality of life. The findings demonstrate the significance of CDC in improving relationship satisfaction and quality of life among HIV serodiscordant couples in China.
ANNALS OF BEHAVIORAL MEDICINE
(2023)
Article
Family Studies
Yumeng Wu, Kathrine Meyers, Lu Xie
Summary: The study revealed that Chinese sexual minority men often face high risk perception, social discrimination, and marginalization in HIV risk management, and their choice of risk management strategies is influenced by their perceptions of the gay community, social norms, and prior experiences. These findings emphasize the importance of considering these factors in planning Pre-Exposure Prophylaxis (PrEP) implementation in China and the need for strategies to address potential PrEP-related stigma among sexual minority men.
CULTURE HEALTH & SEXUALITY
(2022)
Article
Criminology & Penology
Mengyao Lu, Jane Barlow, Franziska Meinck, Yumeng Wu
Summary: This study examines school-based child sexual abuse (CSA) prevention programs and the perspectives of stakeholders in China. The findings indicate a generally positive view of these programs, but also identify important concerns. The study suggests ways to strengthen future CSA prevention programs and research in China.
JOURNAL OF INTERPERSONAL VIOLENCE
(2022)
