FKN Facilitates HK-2 Cell EMT and Tubulointerstitial Lesions via the Wnt/β-Catenin Pathway in a Murine Model of Lupus Nephritis

Fractalkine is Involved in Lipopolysaccharide-Induced Podocyte Injury through the Wnt/β-Catenin Pathway in an Acute Kidney Injury Mouse Model

(2019) Soulixay Senouthai et al.   INFLAMMATION

S3I-201 ameliorates tubulointerstitial lesion of the kidneys in MRL/lpr mice

(2018) Yunxia Du et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oleanolic acid attenuates TGF-β1-induced epithelial-mesenchymal transition in NRK-52E cells

(2018) Wei-ming He et al.   BMC Complementary and Alternative Medicine

Upregulated fractalkine levels in Chinese patients with lupus nephritis

(2018) Yanwu You et al.   CYTOKINE

Cadherin profiling for therapeutic interventions in Epithelial Mesenchymal Transition (EMT) and tumorigenesis

(2018) Mintu Pal et al.   EXPERIMENTAL CELL RESEARCH

Microfluidic co-culture of pancreatic tumor spheroids with stellate cells as a novel 3D model for investigation of stroma-mediated cell motility and drug resistance

(2018) Ji-Hyun Lee et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Thymoquinone inhibits metastatic phenotype and epithelial‑mesenchymal transition in renal cell carcinoma by regulating the LKB1/AMPK signaling pathway

(2018) Bo Kou et al.   ONCOLOGY REPORTS

Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway

(2018) Bohong Cen et al.   Molecular Therapy-Nucleic Acids

TGF-β-Induced CD8+CD103+ Regulatory T Cells Show Potent Therapeutic Effect on Chronic Graft-versus-Host Disease Lupus by Suppressing B Cells

(2018) Haowen Zhong et al.   Frontiers in Immunology

Essential Roles for Mannose-Binding Lectin-Associated Serine Protease-1/3 in the Development of Lupus-Like Glomerulonephritis in MRL/lpr Mice

(2018) Takeshi Machida et al.   Frontiers in Immunology

Tissue-specific Role of CX3CR1 Expressing Immune Cells and Their Relationships with Human Disease

(2018) Myoungsoo Lee et al.   Immune Network

Intrarenal activation of adaptive immune effectors is associated with tubular damage and impaired renal function in lupus nephritis

(2018) Cristina Pamfil et al.   ANNALS OF THE RHEUMATIC DISEASES

Upregulated microRNA-485 suppresses apoptosis of renal tubular epithelial cells in mice with lupus nephritis via regulating the TGF-β-MAPK signaling pathway by inhibiting RhoA expression

(2018) Yu Tian et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis

(2017) Qingjuan Liu et al.   MEDIATORS OF INFLAMMATION

The hormetic functions of Wnt pathways in tubular injury

(2017) Elisabeth F. Gröne et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Elevated levels of soluble fractalkine and increased expression of CX3CR1 in neuropsychiatric systemic lupus erythematosus

(2017) Ling Guo et al.   Experimental and Therapeutic Medicine

GOLPH3 induces epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in epithelial ovarian cancer

(2017) Jing Sun et al.   Cancer Medicine

Wnt/β-catenin signaling and renin–angiotensin system in chronic kidney disease

(2016) Lili Zhou et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Fractalkine/CX3CL1 in rheumatoid arthritis

(2016) Toshihiro Nanki et al.   Modern Rheumatology

The Role of the Rho/ROCK Pathway in Ang II and TGF-β1-Induced Atrial Remodeling

(2016) Li-Juan Liu et al.   PLoS One

MYU, a Target lncRNA for Wnt/c-Myc Signaling, Mediates Induction of CDK6 to Promote Cell Cycle Progression

(2016) Yoshihiro Kawasaki et al.   Cell Reports

Regulation of Renal Fibrosis by Macrophage Polarization

(2015) Bixia Pan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Mesenchymal stem cells promote CD206 expression and phagocytic activity of macrophages through IL-6 in systemic lupus erythematosus

(2015) Wei Deng et al.   CLINICAL IMMUNOLOGY

CX3CR1 Reduces Kidney Fibrosis by Inhibiting Local Proliferation of Profibrotic Macrophages

(2015) Daniel R. Engel et al.   JOURNAL OF IMMUNOLOGY

Methylprednisolone attenuates lipopolysaccharide-induced Fractalkine expression in kidney of Lupus-prone MRL/lpr mice through the NF-kappaB pathway

(2015) Yanwu You et al.   BMC Nephrology

Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-κB Pathway

(2015) Xian Jin et al.   Biomed Research International

Mouse bone marrow-derived mesenchymal stem cells induce macrophage M2 polarization through the nuclear factor-κB and signal transducer and activator of transcription 3 pathways

(2014) Shuo Gao et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

IL-17A produced by bothγδT and Th17 cells promotes renal fibrosis via RANTES-mediated leukocyte infiltration after renal obstruction

(2014) Xiaogang Peng et al.   JOURNAL OF PATHOLOGY

Multiple Genes of the Renin-Angiotensin System Are Novel Targets of Wnt/ -Catenin Signaling

(2014) L. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Aberrant Activation of the WNT/β-Catenin Signaling Pathway in Lupus Nephritis

(2014) Xiao-dong Wang et al.   PLoS One

The transcription factor LEF-1 induces an epithelial–mesenchymal transition in MDCK cells independent of β-catenin

(2013) Wakako Kobayashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The cardiovascular actions of fractalkine/CX3CL1 in the hypothalamic paraventricular nucleus are attenuated in rats with heart failure

(2013) P. J. Ruchaya et al.   EXPERIMENTAL PHYSIOLOGY

Macrophage phenotypes during tissue repair

(2013) Margaret L. Novak et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Functional phenotypes of macrophages and the M1-M2 polarization concept. Part I. Proinflammatory phenotype

(2012) Y. Sh. Schwartz et al.   BIOCHEMISTRY-MOSCOW

HMGB1 mediates IFN-γ-induced cell proliferation in MMC cells through regulation of cyclin D1/CDK4/p16 pathway

(2012) Xiaojuan Feng et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Aberrant Macrophages Mediate Defective Kidney Repair That Triggers Nephritis in Lupus-Susceptible Mice

(2012) Y. Iwata et al.   JOURNAL OF IMMUNOLOGY

Extracellular adenosine signaling induces CX3CL1 expression in the brain to promote experimental autoimmune encephalomyelitis

(2012) Jeffrey H Mills et al.   Journal of Neuroinflammation

Activated innate immunity and the involvement of CX3CR1–fractalkine in promoting hematuria in patients with IgA nephropathy

(2012) Sharon N. Cox et al.   KIDNEY INTERNATIONAL

Autoantibodies in lupus: Culprits or passive bystanders?

(2011) Ole P. Rekvig et al.   AUTOIMMUNITY REVIEWS

Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair

(2011) S. Lee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Predicting outcomes of lupus nephritis with tubulointerstitial inflammation and scarring

(2011) Christine Hsieh et al.   ARTHRITIS CARE & RESEARCH

Lupus nephritis: current update

(2011) Ramesh Saxena et al.   ARTHRITIS RESEARCH & THERAPY

Matrix metalloproteinase 8 deficiency in mice exacerbates inflammatory arthritis through delayed neutrophil apoptosis and reduced caspase 11 expression

(2010) Jennifer H. Cox et al.   ARTHRITIS AND RHEUMATISM

Alterations in Wnt pathway activity in mouse serum and kidneys during lupus development

(2010) Anders Aune Tveita et al.   ARTHRITIS AND RHEUMATISM

Wnt5a Induces Endothelial Inflammation via  -Catenin-Independent Signaling

(2010) J. Kim et al.   JOURNAL OF IMMUNOLOGY

Review: Serum and urine biomarkers of kidney disease: A pathophysiological perspective

(2010) GREG H TESCH   NEPHROLOGY

Chemokines as Novel Therapeutic Targets for Inflammatory Bowel Disease

(2009) Miyuki Nishimura et al.   Annals of the New York Academy of Sciences

Expression of MDC/CCL22 and its receptor CCR4 in rheumatoid arthritis, psoriatic arthritis and osteoarthritis

(2009) Helene Aarslev Flytlie et al.   CYTOKINE

Role of CX3C-chemokine CX3C-L/fractalkine expression in a model of slowly progressive renal failure

(2009) M. J. Koziolek et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols