Emerging Role of Lymphocyte Antigen-6 Family of Genes in Cancer and Immune Cells

Placental expression of AChE, α7nAChR and NF-κB in patients with preeclampsia

(2018) Linmei Zheng et al.   Ginekologia Polska

Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells

(2018) Patrick Fernandes Rodrigues et al.   NATURE IMMUNOLOGY

α7 nicotinic acetylcholine receptors in lung cancer (Review)

(2018) Shengchao Wang et al.   Oncology Letters

Deletion of the Syncytin A receptor Ly6e impairs syncytiotrophoblast fusion and placental morphogenesis causing embryonic lethality in mice

(2018) Michael B. Langford et al.   Scientific Reports

OLFM4, LY6D and S100A7 as potent markers for distant metastasis in estrogen receptor-positive breast carcinoma

(2018) Akifumi Mayama et al.   CANCER SCIENCE

α7nAChR-mediated recruitment of PP1γ promotes TRAF6/NF-κB cascade to facilitate the progression of Hepatocellular Carcinoma

(2018) Chunhua Wan et al.   MOLECULAR CARCINOGENESIS

LY6E mediates an evolutionarily conserved enhancement of virus infection by targeting a late entry step

(2018) Katrina B. Mar et al.   Nature Communications

Determining consistent prognostic biomarkers of overall survival and vascular invasion in hepatocellular carcinoma

(2018) Otília Menyhárt et al.   Royal Society Open Science

SLURP-1 is mutated in Mal de Meleda, a potential molecular signature for melanoma and a putative squamous lineage tumor suppressor gene

(2017) Christina Bergqvist et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

A Cell Fusion-Based Screening Method Identifies Glycosylphosphatidylinositol-Anchored Protein Ly6e as the Receptor for Mouse Endogenous Retroviral Envelope Syncytin-A

(2017) Agathe Bacquin et al.   JOURNAL OF VIROLOGY

α7 nicotinic acetylcholine receptor in tumor-associated macrophages inhibits colorectal cancer metastasis through the JAK2/STAT3 signaling pathway

(2017) Rushan Fei et al.   ONCOLOGY REPORTS

A pathology atlas of the human cancer transcriptome

(2017) Mathias Uhlen et al.   SCIENCE

Label retention and stem cell marker expression in the developing and adult prostate identifies basal and luminal epithelial stem cell subpopulations

(2017) Jens Adam Ceder et al.   Stem Cell Research & Therapy

SCA-1 Expression Level Identifies Quiescent Hematopoietic Stem and Progenitor Cells

(2017) Mina N.F. Morcos et al.   Stem Cell Reports

SCA-1 Labels a Subset of Estrogen-Responsive Bipotential Repopulating Cells within the CD24 + CD49f hi Mammary Stem Cell-Enriched Compartment

(2017) Genevieve V. Dall et al.   Stem Cell Reports

Ly6E/K Signaling to TGF  Promotes Breast Cancer Progression, Immune Escape, and Drug Resistance

(2016) M. AlHossiny et al.   CANCER RESEARCH

PSCA acts as a tumor suppressor by facilitating the nuclear translocation of RB1CC1 in esophageal squamous cell carcinoma

(2016) Li-Yi Zhang et al.   CARCINOGENESIS

Distinct lymphocyte antigens 6 (Ly6) family members Ly6D, Ly6E, Ly6K and Ly6H drive tumorigenesis and clinical outcome

(2016) Linlin Luo et al.   Oncotarget

Epigenetic activation of LY6K predicts the presence of metastasis and poor prognosis in breast carcinoma

(2016) Hyun Kyung Kong et al.   Oncotarget

miRNAs involved in LY6K and estrogen receptor α contribute to tamoxifen-susceptibility in breast cancer

(2016) Ye Sol Kim et al.   Oncotarget

LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis

(2016) Chan Joo Yeom et al.   Oncotarget

Glycerol Monolaurate (GML) inhibits human T cell signaling and function by disrupting lipid dynamics

(2016) Michael S. Zhang et al.   Scientific Reports

PSCA rs2294008 polymorphism contributes to the decreased risk for cervical cancer in a Chinese population

(2016) Shizhi Wang et al.   Scientific Reports

An Antibody-Drug Conjugate Directed against Lymphocyte Antigen 6 Complex, Locus E (LY6E) Provides Robust Tumor Killing in a Wide Range of Solid Tumor Malignancies

(2015) J. Asundi et al.   CLINICAL CANCER RESEARCH

Role of Lynx1 and related Ly6 proteins as modulators of cholinergic signaling in normal and neoplastic bronchial epithelium

(2015) Xiao Wen Fu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Activation of the Macrophage α7 Nicotinic Acetylcholine Receptor and Control of Inflammation

(2015) Carlos A. Báez-Pagán et al.   Journal of Neuroimmune Pharmacology

Ly6h Regulates Trafficking of Alpha7 Nicotinic Acetylcholine Receptors and Nicotine-Induced Potentiation of Glutamatergic Signaling

(2015) C. A. Puddifoot et al.   JOURNAL OF NEUROSCIENCE

PSCA rs2294008 Polymorphism with Increased Risk of Cancer

(2015) Peiliang Geng et al.   PLoS One

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

GPI-Anchored Protein Complex, LY6K/TEX101, Is Required for Sperm Migration into the Oviduct and Male Fertility in Mice1

(2014) Yoshitaka Fujihara et al.   BIOLOGY OF REPRODUCTION

IFN-Stimulated Gene LY6E in Monocytes Regulates the CD14/TLR4 Pathway but Inadequately Restrains the Hyperactivation of Monocytes during Chronic HIV-1 Infection

(2014) Xuan Xu et al.   JOURNAL OF IMMUNOLOGY

Palmoplantar Keratoderma along with Neuromuscular and Metabolic Phenotypes in Slurp1 -Deficient Mice

(2014) Oludotun Adeyo et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Identification of immunogenic LY6K long peptide encompassing both CD4+and CD8+T-cell epitopes and eliciting CD4+T-cell immunity in patients with malignant disease

(2014) Yusuke Tomita et al.   OncoImmunology

The ?7 Nicotinic Acetylcholine Receptor Complex: One, Two or Multiple Drug Targets?

(2013) Morten S. Thomsen et al.   CURRENT DRUG TARGETS

Ly6 family proteins in neutrophil biology

(2013) Pui Y. Lee et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Ly6e expression is restricted to syncytiotrophoblast cells of the mouse placenta

(2013) M. Hughes et al.   PLACENTA

RAG-1 and Ly6D Independently Reflect Progression in the B Lymphoid Lineage

(2013) Qingzhao Zhang et al.   PLoS One

Serological antibodies against LY6K as a diagnostic biomarker in esophageal squamous cell carcinoma

(2012) Bin Zhang et al.   BIOMARKERS

The Regulatory Mechanism of theLY6KGene Expression in Human Breast Cancer Cells

(2012) Hyun Kyung Kong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dendritic Cell-Directed Vaccination with a Lentivector Encoding PSCA for Prostate Cancer in Mice

(2012) Liang Xiao et al.   PLoS One

Reciprocal Metabolic Perturbations in the Adipose Tissue and Liver of GPIHBP1-Deficient Mice

(2011) Michael M. Weinstein et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Genome-wide expression and copy number analysis identifies driver genes in gingivobuccal cancers

(2011) Srikant Ambatipudi et al.   GENES CHROMOSOMES & CANCER

LY6K is a novel molecular target in bladder cancer on basis of integrate genome-wide profiling

(2010) R Matsuda et al.   BRITISH JOURNAL OF CANCER

Tumor Oncogenotypes and Lung Cancer Stem Cell Identity

(2010) James P. Sullivan et al.   Cell Stem Cell

GPIHBP1 and the processing of triglyceride-rich lipoproteins

(2010) Anne P Beigneux   Clinical Lipidology

Towards a knowledge-based Human Protein Atlas

(2010) Mathias Uhlen et al.   NATURE BIOTECHNOLOGY

Lynx1, a Cholinergic Brake, Limits Plasticity in Adult Visual Cortex

(2010) H. Morishita et al.   SCIENCE

GPIHBP1 and lipolysis: an update

(2009) Anne P Beigneux et al.   CURRENT OPINION IN LIPIDOLOGY

Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development

(2009) M. A. Inlay et al.   GENES & DEVELOPMENT

Stem cell antigen 2: a new gene involved in the self-renewal of erythroid progenitors

(2008) C. Bresson-Mazet et al.   CELL PROLIFERATION

In Vitro Whole-Genome Analysis Identifies a Susceptibility Locus for HIV-1

(2008) Corinne Loeuillet et al.   PLOS BIOLOGY