Immune Modulation to Enhance Bone Healing—A New Concept to Induce Bone Using Prostacyclin to Locally Modulate Immunity

Macrophages in bone fracture healing: Their essential role in endochondral ossification

(2018) Claudia Schlundt et al.   BONE

Iloprost Affects Macrophage Activation and CCL2 Concentrations in a Microdialysis Model in Rats

(2018) Kamel Alkhatib et al.   PHARMACEUTICAL RESEARCH

A review of biomaterials in bone defect healing, remaining shortcomings and future opportunities for bone tissue engineering

(2018) T. Winkler et al.   Bone & Joint Research

Clinical and Research Approaches to Treat Non-union Fracture

(2018) Claudia Schlundt et al.   Current Osteoporosis Reports

Mast Cells Are Critical Regulators of Bone Fracture-Induced Inflammation and Osteoclast Formation and Activity

(2017) Jochen Kroner et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Long-term clinical stabilization of scleroderma patients treated with a chronic and intensive IV iloprost regimen

(2016) Rosario Foti et al.   RHEUMATOLOGY INTERNATIONAL

Role of inflammation in the aging bones

(2015) Samir M. Abdelmagid et al.   LIFE SCIENCES

Boon and Bane of Inflammation in Bone Tissue Regeneration and Its Link with Angiogenesis

(2015) Katharina Schmidt-Bleek et al.   TISSUE ENGINEERING PART B-REVIEWS

Initiation and early control of tissue regeneration – bone healing as a model system for tissue regeneration

(2014) Katharina Schmidt-Bleek et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Fracture healing: mechanisms and interventions

(2014) Thomas A. Einhorn et al.   Nature Reviews Rheumatology

Terminally Differentiated CD8+ T Cells Negatively Affect Bone Regeneration in Humans

(2013) S. Reinke et al.   Science Translational Medicine

PGI2as a Regulator of Inflammatory Diseases

(2012) Stacy L. Dorris et al.   MEDIATORS OF INFLAMMATION

Cost Effectiveness of Prostacyclins in Pulmonary Arterial Hypertension

(2012) Antonio Roman et al.   Applied Health Economics and Health Policy

Novel Mechanism of the Vascular Protector Prostacyclin: Regulating MicroRNA Expression

(2011) Anita Mohite et al.   BIOCHEMISTRY

Iloprost modulates the immune response in systemic sclerosis

(2011) Patrizia D'Amelio et al.   BMC IMMUNOLOGY

Digitale Ulzera bei systemischer Sklerose: Diagnostik und Therapie

(2011) G. Riemekasten et al.   DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT

The biology of fracture healing

(2011) Richard Marsell et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Hypoxia upregulates PGI-synthase and increases PGI2release in human vascular cells exposed to inflammatory stimuli

(2011) Mercedes Camacho et al.   JOURNAL OF LIPID RESEARCH

Iloprost has potent anti-inflammatory properties on human monocyte-derived dendritic cells

(2010) T. Müller et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Efficiency of iloprost treatment for osseous malperfusion

(2010) Marcus Jäger et al.   INTERNATIONAL ORTHOPAEDICS

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

(2010) Mary L Bouxsein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

MRI-Demonstrated Outcome of Subchondral Stress Fractures of the Knee After Treatment with Iloprost or Tramadol: Observations in 14 Patients

(2009) Marius E Mayerhoefer et al.   CLINICAL JOURNAL OF SPORT MEDICINE

Differential regulation of blood vessel formation between standard and delayed bone healing

(2009) Jasmin Lienau et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Cellular composition of the initial fracture hematoma compared to a muscle hematoma: A study in sheep

(2009) Katharina Schmidt-Bleek et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Insight into the Molecular Pathophysiology of Delayed Bone Healing in a Sheep Model

(2009) Jasmin Lienau et al.   TISSUE ENGINEERING PART A