Lamiaceae: An Insight on Their Anti-Allergic Potential and Its Mechanisms of Action

Immunomodulation Effects of Schizonepeta tenuifolia Briq. on the IgE-Induced Allergic Model of RBL-2H3 Cells

(2018) Yi-Hsuan Lin et al.   Evidence-based Complementary and Alternative Medicine

New mechanism underlying IL-31–induced atopic dermatitis

(2018) Jianghui Meng et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Anti-Nociceptive Effect and Standardization from Mixture of Agrimonia pilosa Ledeb and Salvia miltiorrhiza Bunge Extracts

(2018) Seung Hwan Hwang et al.   JOURNAL OF MEDICINAL FOOD

Mast cells, basophils and eosinophils: From allergy to cancer

(2018) A. Rigoni et al.   SEMINARS IN IMMUNOLOGY

Medicinal Plants of the Family Lamiaceae in Pain Therapy: A Review

(2018) Cristina M. Uritu et al.   Pain Research & Management

Phytochemical Composition, Antioxidant Potential and Cholinesterase Inhibition Potential of Extracts from Mentha pulegium L.

(2018) Olivera Politeo et al.   CHEMISTRY & BIODIVERSITY

Pogostemins A-C, three new cytotoxic meroterpenoids from Pogostemon auricularius

(2018) Hoai Thi Nguyen et al.   FITOTERAPIA

Sesquiterpenoids from Vitex pierreana

(2018) Qi Ye et al.   FITOTERAPIA

Rosmarinus officinalis essential oil: A review of its phytochemistry, anti-inflammatory activity, and mechanisms of action involved

(2018) Raphaelle Sousa Borges et al.   JOURNAL OF ETHNOPHARMACOLOGY

Phytochemical and phytopharmacological review of Perilla frutescens L. (Labiatae), a traditional edible-medicinal herb in China

(2017) Hua Yu et al.   FOOD AND CHEMICAL TOXICOLOGY

Determination of podophyllotoxin and related aryltetralin lignans by HPLC/DAD/MS from Lamiaceae species

(2017) Hugo N. Brandão et al.   MICROCHEMICAL JOURNAL

Mentha arvensis essential oil suppressed airway changes induced by histamine and ovalbumin in experimental animals

(2017) Shilpa Sharma et al.   NATURAL PRODUCT RESEARCH

Flavonoid Constituents of Phlomis (Lamiaceae) Species Using Liquid Chromatography Mass Spectrometry

(2017) Fatemeh Aghakhani et al.   PHYTOCHEMICAL ANALYSIS

Phytochemical screening and biological activity of Lamiaceae family plant extracts

(2017) Ileana Cocan et al.   Experimental and Therapeutic Medicine

Skullcap (Scutellaria Baicalensis) Hexane Fraction Inhibits the Permeation of Ovalbumin and Regulates Th1/2 Immune Responses

(2017) Sun Jung et al.   Nutrients

The Effect of Zataria multiflora on Th1/Th2 and Th17/T Regulatory in a Mouse Model of Allergic Asthma

(2017) Majid Kianmehr et al.   Frontiers in Pharmacology

A New Compound, 1H,8H-Pyrano[3,4-C]Pyran-1,8-Dione, Suppresses Airway Epithelial Cell Inflammatory Responses in a Murine Model of Asthma

(2017) H. Lee et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Anti-allergic activity of glycyrrhizic acid on IgE-mediated allergic reaction by regulation of allergy-related immune cells

(2017) Shiwen Han et al.   Scientific Reports

Perilla leaf extract prevents atopic dermatitis induced by an extract of Dermatophagoides farinae in NC/Nga mice

(2016)   ASIAN PACIFIC JOURNAL OF ALLERGY AND IMMUNOLOGY

Medicinal plants of the family Lamiaceae as functional foods – a review  

(2016) K. Carović-Stanko et al.   CZECH JOURNAL OF FOOD SCIENCES

Inhibition of Asthma in OVA Sensitized Mice Model by a Traditional Uygur Herb Nepeta bracteata Benth.

(2016) Jing Wang et al.   Evidence-based Complementary and Alternative Medicine

Report on the Medicinal Use of Eleven Lamiaceae Species in Lebanon and Rationalization of Their Antimicrobial Potential by Examination of the Chemical Composition and Antimicrobial Activity of Their Essential Oils

(2016) Madona Khoury et al.   Evidence-based Complementary and Alternative Medicine

Oroxylin A Inhibits Allergic Airway Inflammation in Ovalbumin (OVA)-Induced Asthma Murine Model

(2016) De-Gang Zhou et al.   INFLAMMATION

Regulatory T cells in allergic diseases

(2016) Magali Noval Rivas et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Effects of thymol and carvacrol on T-helper cell subset cytokines and their main transcription factors in ovalbumin-immunized mice

(2016) Nasser Gholijani et al.   Journal of Immunotoxicology

A rapid and sensitive assay based on particle analysis for cell degranulation detection in basophils and mast cells

(2016) Lufen Huang et al.   PHARMACOLOGICAL RESEARCH

Baicalein induces CD4+Foxp3+ T cells and enhances intestinal barrier function in a mouse model of food allergy

(2016) Min-Jung Bae et al.   Scientific Reports

Diagnostic Utility of Total IgE in Foods, Inhalant, and Multiple Allergies in Saudi Arabia

(2016) Jamil A. Al-Mughales   Journal of Immunology Research

Scutellaria baicalensis , the golden herb from the garden of Chinese medicinal plants

(2016) Qing Zhao et al.   Science Bulletin

Ethanol Extract ofPerilla frutescensSuppresses Allergen-Specific Th2 Responses and Alleviates Airway Inflammation and Hyperreactivity in Ovalbumin-Sensitized Murine Model of Asthma

(2015) Miaw-Ling Chen et al.   Evidence-based Complementary and Alternative Medicine

High antiallergic activity of 5,6,4′-trihydroxy-7,8,3′-trimethoxyflavone and 5,6-dihydroxy-7,8,3′,4′-tetramethoxyflavone from eau de cologne mint (Mentha×piperita citrata)

(2015) Akihiko Sato et al.   FITOTERAPIA

Anti-allergic and anti-inflammatory effects of aqueous extract of Pogostemon cablin

(2015) SEOK CHEOL YOON et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

15,16-Dihydrotanshinone I suppresses IgE-Ag stimulated mouse bone marrow-derived mast cell activation by inhibiting Syk kinase

(2015) Xian Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

Plants with topical uses in the Ripollès district (Pyrenees, Catalonia, Iberian Peninsula): Ethnobotanical survey and pharmacological validation in the literature

(2015) Montse Rigat et al.   JOURNAL OF ETHNOPHARMACOLOGY

Topical application ofScutellaria baicalensissuppresses 2,4-dinitrochlorobenzene-induced contact dermatitis

(2015) Tae-Won Kim et al.   NATURAL PRODUCT RESEARCH

Spectrophotometric determination of the total flavonoid content in Ocimum basilicum L. (Lamiaceae) leaves

(2015) Luciano Soares et al.   Pharmacognosy Magazine

Inhibition of Three Novel Radix Scutellariae Extracts on Immediate Hypersensitivity

(2014) X Li et al.   African Journal of Traditional Complementary and Alternative Medicines

Salvia plebeia Suppresses Atopic Dermatitis-Like Skin Lesions

(2014) Jin Kyeong Choi et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Why Africa matters: evolution of Old World Salvia (Lamiaceae) in Africa

(2014) Maria Will et al.   ANNALS OF BOTANY

Thymol attenuates allergic airway inflammation in ovalbumin (OVA)-induced mouse asthma

(2014) Ershun Zhou et al.   FITOTERAPIA

Screening of Mammalian DNA Polymerase Inhibitors from Rosemary Leaves and Analysis of the Anti-inflammatory and Antiallergic Effects of the Isolated Compounds

(2014) Yoshiyuki Mizushina et al.   FOOD SCIENCE AND TECHNOLOGY RESEARCH

Phytochemical screening of antioxidant and antibacterial activities of methanolic extracts of some Lamiaceae

(2014) Nabyla Khaled-Khodja et al.   INDUSTRIAL CROPS AND PRODUCTS

Rosmarinic Acid Extract for Antioxidant, Antiallergic, and α-Glucosidase Inhibitory Activities, Isolated by Supramolecular Technique and Solvent Extraction from Perilla Leaves

(2014) Fengxian Zhu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Preventive effects of skullcap (Scutellaria baicalensis) extract in a mouse model of food allergy

(2014) Hee Soon Shin et al.   JOURNAL OF ETHNOPHARMACOLOGY

Does β-Hexosaminidase Function Only as a Degranulation Indicator in Mast Cells? The Primary Role of β-Hexosaminidase in Mast Cell Granules

(2014) Nobuyuki Fukuishi et al.   JOURNAL OF IMMUNOLOGY

Subsets of regulatory T cells and their roles in allergy

(2014) Huiyun Zhang et al.   Journal of Translational Medicine

Skullcap (Scutellaria baicalensis) Extract and Its Active Compound, Wogonin, Inhibit Ovalbumin-Induced Th2-Mediated Response

(2014) Hee Shin et al.   MOLECULES

Anti-Inflammatory and Antipruritic Effects of Luteolin from Perilla (P. frutescens L.) Leaves

(2014) In Jeon et al.   MOLECULES

The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety

(2014) Martins Ekor   Frontiers in Pharmacology

Allergic diseases and asthma: a global public health concern and a call to action

(2014) Ruby Pawankar   World Allergy Organization Journal

Identification of a Nitric Oxide Generation-Stimulative Principle inScutellariae radix

(2013) Ziyang CHEN et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Cytotoxic impact of phenolics from Lamiaceae species on human breast cancer cells

(2013) Izabela Berdowska et al.   FOOD CHEMISTRY

Experimental study on antinociceptive and anti-allergy effects of patchouli oil

(2013) Jing-Jin He et al.   JOURNAL OF ESSENTIAL OIL RESEARCH

The impact of Zataria multiflora Boiss extract on in vitro and in vivo Th1/Th2 cytokine (IFN-γ/IL4) balance

(2013) Mohammad Hossein Boskabady et al.   JOURNAL OF ETHNOPHARMACOLOGY

Targeting eosinophils in allergy, inflammation and beyond

(2013) Patricia C. Fulkerson et al.   NATURE REVIEWS DRUG DISCOVERY

Assessment of Dermal Safety of Scutellaria baicalensis Aqueous Extract Topical Application on Skin Hypersensitivity

(2013) Tae-Won Kim et al.   PLANTA MEDICA

Th17 Immunity in Children with Allergic Asthma and Rhinitis: A Pharmacological Approach

(2013) Giusy Daniela Albano et al.   PLoS One

Regulatory CD4+Foxp3+ T Cells Control the Severity of Anaphylaxis

(2013) Reem Kanjarawi et al.   PLoS One

Perilla frutescens Leaf Extract Inhibits Mite Major Allergen Der p 2-induced Gene Expression of Pro-Allergic and Pro-Inflammatory Cytokines in Human Bronchial Epithelial Cell BEAS-2B

(2013) Jer-Yuh Liu et al.   PLoS One

An ethnopharmacological investigation of medicinal Salvia plants (Lamiaceae) in China

(2013) Minhui Li et al.   Acta Pharmaceutica Sinica B

H1 Antihistamines: Current Status and Future Directions

(2013) F. Estelle R. Simon et al.   World Allergy Organization Journal

Phyto-chemical analysis, anti-allergic and anti-inflammatory activity of Mentha arvensis in animals

(2012) Farnaz Malik   African Journal of Pharmacy and Pharmacology

Aqueous Extract of Mosla chinensis Inhibits Mast Cell-Mediated Allergic Inflammation

(2012) Hui-Hun Kim et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Effects of Thymol and Carvacrol, Constituents ofThymus vulgarisL. Essential Oil, on the Inflammatory Response

(2012) Fernanda Carolina Fachini-Queiroz et al.   Evidence-based Complementary and Alternative Medicine

Vitex rotundifolia L. prevented airway eosinophilic inflammation and airway remodeling in an ovalbumin-induced asthma mouse model

(2012) Hyunsu Bae et al.   INTERNATIONAL IMMUNOLOGY

Ocimum gratissimum Linn. and rosmarinic acid, attenuate eosinophilic airway inflammation in an experimental model of respiratory allergy to Blomia tropicalis

(2012) Ryan Santos Costa et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Antiallergic effects of Scutellaria baicalensis on inflammation in vivo and in vitro

(2012) Hyuk-Sang Jung et al.   JOURNAL OF ETHNOPHARMACOLOGY

Acute and sub-chronic toxicity studies of Danshen injection in Sprague-Dawley rats

(2012) Meng Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Schizonepeta tenuifoliaInhibits the Development of Atopic Dermatitis in Mice

(2012) You Yeon Choi et al.   PHYTOTHERAPY RESEARCH

Studies on the Constituents of Lagochilus leiacanthus (Labiatae)

(2011) Megumi Furukawa et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Elsholtzia ciliata inhibits mast cell-mediated allergic inflammation: role of calcium, p38 mitogen-activated protein kinase and nuclear factor-κB

(2011) Hui-Hun Kim et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Regulatory T cells and Foxp3

(2011) Alexander Y. Rudensky   IMMUNOLOGICAL REVIEWS

Alleviation of atopic dermatitis-related symptoms by Perilla frutescens Britton

(2011) Sang-Han Lee   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Inhibitory effects of casticin on migration of eosinophil and expression of chemokines and adhesion molecules in A549 lung epithelial cells via NF-κB inactivation

(2011) Duck-jae Koh et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antitussive and toxicological evaluation ofVitex negundo

(2011) Rizwan-ul Haq et al.   NATURAL PRODUCT RESEARCH

Monoterpenes Isolated fromMinthostachys verticillata(Griseb.) Epling Essential Oil Modulates Immediate-Type Hypersensitivity ResponsesIn VitroandIn Vivo

(2011) Laura Cariddi et al.   PLANTA MEDICA

Anti-pruritic effect of baicalin and its metabolites, baicalein and oroxylin A, in mice

(2010) Hien-trung Trinh et al.   ACTA PHARMACOLOGICA SINICA

Hyaluronidase Inhibitors from Takuran, Lycopus lucidus

(2010) Toshihiro Murata et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Role of Treg in immune regulation of allergic diseases

(2010) Oscar Palomares et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Clinopodium gracile inhibits mast cell-mediated allergic inflammation: involvement of calcium and nuclear factor-κB

(2010) Seung-Bin Park et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

IgE, mast cells, basophils, and eosinophils

(2010) Kelly D. Stone et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Tanshinones isolated from the rhizome of Salvia miltiorrhiza inhibit passive cutaneous anaphylaxis reaction in mice

(2010) Hien Trung Trinh et al.   JOURNAL OF ETHNOPHARMACOLOGY

Anti-asthmatic effects of phenylpropanoid glycosides from Clerodendron trichotomum leaves and Rumex gmelini herbes in conscious guinea-pigs challenged with aerosolized ovalbumin

(2010) Ji Yun Lee et al.   PHYTOMEDICINE

Protective Effects of Mentha haplocalyx Ethanol Extract (MH) in a Mouse Model of Allergic Asthma

(2010) Mee-Young Lee et al.   PHYTOTHERAPY RESEARCH

A new furofuran lignan from Isodon japonicus

(2009) Seong Su Hong et al.   ARCHIVES OF PHARMACAL RESEARCH

Histamine, histamine receptors and their role in immune pathology

(2009) M. Jutel et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Determination of toxic perilla ketone, secondary plant metabolites and antioxidative capacity in five Perilla frutescens L. varieties

(2009) Franziska Müller-Waldeck et al.   FOOD AND CHEMICAL TOXICOLOGY

Complementary and alternative medicine for the allergist-immunologist: Where do I start?

(2009) Renata J.M. Engler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Anti-inflammatory effects of Scutellaria baicalensis water extract on LPS-activated RAW 264.7 macrophages

(2009) Seok-Bin Yoon et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antiallergic Herbal Composition fromScutellaria baicalensisandPhyllostachys edulis

(2009) Dong-Seon Kim et al.   PLANTA MEDICA

Anti-allergic activity of an ethanol extract from Salviae miltiorrhiza

(2008) Ju Hye Yang et al.   ARCHIVES OF PHARMACAL RESEARCH

Anti-allergic effects of Teucrium japonicum on mast cell-mediated allergy model

(2008) Sang-Hyun Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

T-cell effector pathways in allergic diseases: Transcriptional mechanisms and therapeutic targets

(2008) Talal A. Chatila et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The development of allergic inflammation

(2008) Stephen J. Galli et al.   NATURE

Toxicological studies of wogonin in experimental animals

(2008) Qi Qi et al.   PHYTOTHERAPY RESEARCH

Th17 and Allergy

(2008) Keisuke Oboki et al.   ALLERGOLOGY INTERNATIONAL

Phlomis umbrosa root inhibits mast cell-dependent allergic reactions and inflammatory cytokine secretion

(2007) Tae-Yong Shin et al.   PHYTOTHERAPY RESEARCH