Levodopa/Benserazide PLGA Microsphere Prevents L-Dopa–Induced Dyskinesia via Lower β-Arrestin2 in 6-Hydroxydopamine Parkinson’s Rats

Modulation of CaMKIIa-GluN2B interaction in levodopa-induced dyskinesia in 6-OHDA-lesioned Parkinson’s rats

(2018) Xin-Shi Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Potential for targeting dopamine/DARPP-32 signaling in neuropsychiatric and neurodegenerative disorders

(2017) Akinori Nishi et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Dopamine-Induced Changes in Gαolf Protein Levels in Striatonigral and Striatopallidal Medium Spiny Neurons Underlie the Genesis of l-DOPA-Induced Dyskinesia in Parkinsonian Mice

(2017) Ryoma Morigaki et al.   Frontiers in Cellular Neuroscience

Levodopa/Benserazide Loaded Microspheres Alleviate L-dopa Induced Dyskinesia through Preventing the Over-Expression of D1R/Shp-2/ERK1/2 Signaling Pathway in a Rat Model of Parkinson's Disease

(2017) Ying Wan et al.   Frontiers in Aging Neuroscience

Maladaptive Synaptic Plasticity in L-DOPA-Induced Dyskinesia

(2016) Qiang Wang et al.   Frontiers in Neural Circuits

Inhibition of Glycogen Synthase Kinase-3β (GSK-3β) as potent therapeutic strategy to ameliorates L-dopa-induced dyskinesia in 6-OHDA parkinsonian rats

(2016) Cheng-long Xie et al.   Scientific Reports

Internalization and desensitization of the human glucose-dependent-insulinotropic receptor is affected by N-terminal acetylation of the agonist

(2015) Sadek Ismail et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Targeting β-arrestin2 in the treatment of l-DOPA–induced dyskinesia in Parkinson’s disease

(2015) Nikhil M. Urs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Presynaptic effects of levodopa and their possible role in dyskinesia

(2014) Eugene V. Mosharov et al.   MOVEMENT DISORDERS

Continuous dopaminergic stimulation (CDS)-based treatment in Parkinson's disease patients with motor complications: A systematic review and meta-analysis

(2014) Cheng-long Xie et al.   Scientific Reports

Levodopa/benserazide microsphere (LBM) prevents L-dopa induced dyskinesia by inactivation of the DR1/PKA/P-tau pathway in 6-OHDA-lesioned Parkinson's rats

(2014) Cheng-long Xie et al.   Scientific Reports

Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy study

(2013) C Warren Olanow et al.   LANCET NEUROLOGY

Levodopa-induced dyskinesias in Parkinson’s disease: emerging treatments

(2013) Spyridon Konitsiotis et al.   Neuropsychiatric Disease and Treatment

Controlled-release levodopa methyl ester/benserazide-loaded nanoparticles ameliorate levodopa-induced dyskinesia in rats

(2012) Weien Yuan et al.   International Journal of Nanomedicine

Levodopa/benserazide microspheres reduced levodopa-induced dyskinesia by downregulating phosphorylated GluR1 expression in 6-OHDA-lesioned rats

(2012) Weien Yuan et al.   Drug Design Development and Therapy

Crystal Structure of Arrestin-3 Reveals the Basis of the Difference in Receptor Binding Between Two Non-visual Subtypes

(2011) Xuanzhi Zhan et al.   JOURNAL OF MOLECULAR BIOLOGY

Milestones in Parkinson's disease therapeutics

(2011) Olivier Rascol et al.   MOVEMENT DISORDERS

Sustained-release formulation of levodopa methyl ester/benserazide for prolonged suppressing dyskinesia expression in 6-OHDA-leisoned rats

(2011) Tiantian Ren et al.   NEUROSCIENCE LETTERS

L-DOPA-Induced Dyskinesia and Abnormal Signaling in Striatal Medium Spiny Neurons: Focus on Dopamine D1 Receptor-Mediated Transmission

(2011) Michael Feyder et al.   Frontiers in Behavioral Neuroscience

Levodopa-induced dyskinesias in patients with Parkinson's disease: filling the bench-to-bedside gap

(2010) Paolo Calabresi et al.   LANCET NEUROLOGY

Genetic Inactivation of Dopamine D1 but Not D2 Receptors Inhibits L-DOPA–Induced Dyskinesia and Histone Activation

(2009) Sanja Darmopil et al.   BIOLOGICAL PSYCHIATRY

Pharmacokinetics and pharmacodynamics of levodopa

(2008) John G. Nutt   MOVEMENT DISORDERS