R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma

Further delineation of the SOX18 -related Hypotrichosis, Lymphedema, Telangiectasia syndrome (HTLS)

(2018) Irene Valenzuela et al.   European Journal of Medical Genetics

Role of the SOX18 protein in neoplastic processes (Review)

(2018) Mateusz Olbromski et al.   Oncology Letters

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice

(2017) Jeroen Overman et al.   eLife

Aortic Dilatation Associated With a De Novo Mutation in the SOX18 Gene: Expanding the Clinical Spectrum of Hypotrichosis-Lymphedema-Telangiectasia Syndrome

(2016) Florian Wünnemann et al.   CANADIAN JOURNAL OF CARDIOLOGY

A novel SOX18 mutation uncovered in Jordanian patient with hypotrichosis–lymphedema–telangiectasia syndrome by Whole Exome Sequencing

(2016) Fatma Bastaki et al.   MOLECULAR AND CELLULAR PROBES

Infantile hemangioma-derived stem cells and endothelial cells are inhibited by class 3 semaphorins

(2015) Hironao Nakayama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Gateway-compatible vectors for high-throughput protein expression in pro- and eukaryotic cell-free systems

(2015) Dejan Gagoski et al.   JOURNAL OF BIOTECHNOLOGY

Propranolol Reduces Cancer Risk

(2015) Ping-Ying Chang et al.   MEDICINE

Oral Propranolol for Infantile Hemangioma

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

A Randomized, Controlled Trial of Oral Propranolol in Infantile Hemangioma

(2015) Christine Léauté-Labrèze et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma

(2015) Jennifer K Wolter et al.   Oncotarget

Propranolol targets the contractility of infantile haemangioma-derived pericytes

(2014) D. Lee et al.   BRITISH JOURNAL OF DERMATOLOGY

Hypotrichosis-lymphedema-telangiectasia-renal defect associated with a truncating mutation in the SOX18 gene

(2014) S. Moalem et al.   CLINICAL GENETICS

Rapid Mapping of Interactions between Human SNX-BAR Proteins MeasuredIn Vitroby AlphaScreen and Single-molecule Spectroscopy

(2014) Emma Sierecki et al.   MOLECULAR & CELLULAR PROTEOMICS

β-blockers increase response to chemotherapy via direct antitumour and anti-angiogenic mechanisms in neuroblastoma

(2013) E Pasquier et al.   BRITISH JOURNAL OF CANCER

Serum-Level Changes of Vascular Endothelial Growth Factor in Children with Infantile Hemangioma after Oral Propranolol Therapy

(2013) Xiao Dong Chen et al.   PEDIATRIC DERMATOLOGY

Propranolol therapy of infantile hemangiomas: efficacy, adverse effects, and recurrence

(2013) Qiang Xiao et al.   PEDIATRIC SURGERY INTERNATIONAL

Propranolol Accelerates Adipogenesis in Hemangioma Stem Cells and Causes Apoptosis of Hemangioma Endothelial Cells

(2013) Alvin Wong et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Induction of apoptosis in infantile hemangioma endothelial cells by propranolol

(2013) JUN-BO TU et al.   Experimental and Therapeutic Medicine

A cell-free approach to accelerate the study of protein-protein interactions in vitro

(2013) E. Sierecki et al.   Interface Focus

Attenuation of Choroidal Neovascularization by β2-Adrenoreceptor Antagonism

(2013) Jeremy A. Lavine et al.   JAMA Ophthalmology

Studies on Axenfeld-Rieger syndrome patients and mice reveal Foxc1's role in corneal neovascularization

(2012) M. Francois et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Propranolol as an Alternative Treatment Option for Pediatric Lymphatic Malformation

(2012) Michio Ozeki et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

VEGFR-1 Mediates Endothelial Differentiation and Formation of Blood Vessels in a Murine Model of Infantile Hemangioma

(2011) Elisa Boscolo et al.   AMERICAN JOURNAL OF PATHOLOGY

Leishmania cell-free protein expression system

(2011) Oleksiy Kovtun et al.   METHODS

Recurrence of Infantile Hemangiomas Treated with Propranolol

(2011) Lorea Bagazgoitia et al.   PEDIATRIC DERMATOLOGY

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma

(2010) June K. Wu et al.   ANGIOGENESIS

Role of β1-adrenoceptor in increased lipolysis in cancer cachexia

(2010) Dong-xing Cao et al.   CANCER SCIENCE

Propranolol suppresses angiogenesis in vitro: Inhibition of proliferation, migration, and differentiation of endothelial cells

(2010) Sylvie Lamy et al.   VASCULAR PHARMACOLOGY

Sox7 and Sox17 are strain-specific modifiers of the lymphangiogenic defects caused by Sox18 dysfunction in mice

(2009) B. Hosking et al.   DEVELOPMENT

Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation

(2009) Meredith Downes et al.   HUMAN MOLECULAR GENETICS

Species-independent translational leaders facilitate cell-free expression

(2009) Sergei Mureev et al.   NATURE BIOTECHNOLOGY

Standardization of real-time PCR gene expression data from independent biological replicates

(2008) Erik Willems et al.   ANALYTICAL BIOCHEMISTRY

Multipotential stem cells recapitulate human infantile hemangioma in immunodeficient mice

(2008) Zia A. Khan et al.   JOURNAL OF CLINICAL INVESTIGATION

Sox18 induces development of the lymphatic vasculature in mice

(2008) Mathias François et al.   NATURE

Propranolol for Severe Hemangiomas of Infancy

(2008) Christine Léauté-Labrèze et al.   NEW ENGLAND JOURNAL OF MEDICINE