Absolute quantification of cohesin, CTCF and their regulators in human cells

Determining cellular CTCF and cohesin abundances to constrain 3D genome models

(2019) Claudia Cattoglio et al.   eLife

The Cohesin Ring Uses Its Hinge to Organize DNA Using Non-topological as well as Topological Mechanisms

(2018) Madhusudhan Srinivasan et al.   CELL

Establishing and dissolving cohesion during the vertebrate cell cycle

(2018) Carmen Morales et al.   CURRENT OPINION IN CELL BIOLOGY

Dynamics of sister chromatid resolution during cell cycle progression

(2018) Rugile Stanyte et al.   JOURNAL OF CELL BIOLOGY

A quantitative map of human Condensins provides new insights into mitotic chromosome architecture

(2018) Nike Walther et al.   JOURNAL OF CELL BIOLOGY

Scc2 Is a Potent Activator of Cohesin’s ATPase that Promotes Loading by Binding Scc1 without Pds5

(2018) Naomi J. Petela et al.   MOLECULAR CELL

Quantitative mapping of fluorescently tagged cellular proteins using FCS-calibrated four-dimensional imaging

(2018) Antonio Z Politi et al.   Nature Protocols

A pathway for mitotic chromosome formation

(2018) Johan H. Gibcus et al.   SCIENCE

Real-time imaging of DNA loop extrusion by condensin

(2018) Mahipal Ganji et al.   SCIENCE

TADs are 3D structural units of higher-order chromosome organization in Drosophila

(2018) Quentin Szabo et al.   Science Advances

In Vivo Evidence for ATPase-Dependent DNA Translocation by the Bacillus subtilis SMC Condensin Complex

(2018) Xindan Wang et al.   MOLECULAR CELL

Experimental and computational framework for a dynamic protein atlas of human cell division

(2018) Yin Cai et al.   NATURE

Towards a Unified Model of SMC Complex Function

(2018) Markus Hassler et al.   CURRENT BIOLOGY

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Super-resolution chromatin tracing reveals domains and cooperative interactions in single cells

(2018) Bogdan Bintu et al.   SCIENCE

Two independent modes of chromatin organization revealed by cohesin removal

(2017) Wibke Schwarzer et al.   NATURE

Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl

(2017) Georg A. Busslinger et al.   NATURE

Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition

(2017) Ilya M. Flyamer et al.   NATURE

3D structures of individual mammalian genomes studied by single-cell Hi-C

(2017) Tim J. Stevens et al.   NATURE

Cell-cycle dynamics of chromosomal organization at single-cell resolution

(2017) Takashi Nagano et al.   NATURE

Bacillus subtilis SMC complexes juxtapose chromosome arms as they travel from origin to terminus

(2017) Xindan Wang et al.   SCIENCE

The condensin complex is a mechanochemical motor that translocates along DNA

(2017) Tsuyoshi Terakawa et al.   SCIENCE

Scc2/Nipbl hops between chromosomal cohesin rings after loading

(2017) James Rhodes et al.   eLife

CTCF and cohesin regulate chromatin loop stability with distinct dynamics

(2017) Anders S Hansen et al.   eLife

Sororin actively maintains sister chromatid cohesion

(2016) Rene Ladurner et al.   EMBO JOURNAL

Rapid movement and transcriptional re‐localization of human cohesin on DNA

(2016) Iain F Davidson et al.   EMBO JOURNAL

Cohesin acetylation and Wapl‐Pds5 oppositely regulate translocation of cohesin along DNA

(2016) Mai Kanke et al.   EMBO JOURNAL

Super-resolution imaging reveals distinct chromatin folding for different epigenetic states

(2016) Alistair N. Boettiger et al.   NATURE

Single-Molecule Imaging Reveals a Collapsed Conformational State for DNA-Bound Cohesin

(2016) Johannes Stigler et al.   Cell Reports

Formation of Chromosomal Domains by Loop Extrusion

(2016) Geoffrey Fudenberg et al.   Cell Reports

Evidence for cohesin sliding along budding yeast chromosomes

(2016) Maria Ocampo-Hafalla et al.   Open Biology

Functional role of dimerization and CP190 interacting domains of CTCF protein in Drosophila melanogaster

(2015) Artem Bonchuk et al.   BMC BIOLOGY

CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function

(2015) Ya Guo et al.   CELL

CTCF Binding Polarity Determines Chromatin Looping

(2015) Elzo de Wit et al.   MOLECULAR CELL

High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells

(2015) Malte Wachsmuth et al.   NATURE BIOTECHNOLOGY

Biological chromodynamics: a general method for measuring protein occupancy across the genome by calibrating ChIP-seq

(2015) Bin Hu et al.   NUCLEIC ACIDS RESEARCH

Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes

(2015) Adrian L. Sanborn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SiR–Hoechst is a far-red DNA stain for live-cell nanoscopy

(2015) Gražvydas Lukinavičius et al.   Nature Communications

Comparative Hi-C Reveals that CTCF Underlies Evolution of Chromosomal Domain Architecture

(2015) Matteo Vietri Rudan et al.   Cell Reports

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

(2014) Suhas S.P. Rao et al.   CELL

Cohesin’s ATPase Activity Couples Cohesin Loading onto DNA with Smc3 Acetylation

(2014) Rene Ladurner et al.   CURRENT BIOLOGY

MS Amanda, a Universal Identification Algorithm Optimized for High Accuracy Tandem Mass Spectra

(2014) Viktoria Dorfer et al.   JOURNAL OF PROTEOME RESEARCH

Characterization of a DNA exit gate in the human cohesin ring

(2014) P. J. Huis in 't Veld et al.   SCIENCE

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

(2013) F. Ann Ran et al.   CELL

Prophase pathway-dependent removal of cohesin from human chromosomes requires opening of the Smc3–Scc1 gate

(2013) Johannes Buheitel et al.   EMBO JOURNAL

Disengaging the Smc3/kleisin interface releases cohesin from Drosophila chromosomes during interphase and mitosis

(2013) Christian S Eichinger et al.   EMBO JOURNAL

Single-cell Hi-C reveals cell-to-cell variability in chromosome structure

(2013) Takashi Nagano et al.   NATURE

Biochemical reconstitution of topological DNA binding by the cohesin ring

(2013) Yasuto Murayama et al.   NATURE

Wapl is an essential regulator of chromatin structure and chromosome segregation

(2013) Antonio Tedeschi et al.   NATURE

The Genomic and Transcriptomic Landscape of a HeLa Cell Line

(2013) Jonathan J. M. Landry et al.   G3-Genes Genomes Genetics

Cohesin’s DNA Exit Gate Is Distinct from Its Entrance Gate and Is Regulated by Acetylation

(2012) Kok-Lung Chan et al.   CELL

Topological domains in mammalian genomes identified by analysis of chromatin interactions

(2012) Jesse R. Dixon et al.   NATURE

Spatial partitioning of the regulatory landscape of the X-inactivation centre

(2012) Elphège P. Nora et al.   NATURE

Selected reaction monitoring–based proteomics: workflows, potential, pitfalls and future directions

(2012) Paola Picotti et al.   NATURE METHODS

Handcuff for sisters: A new model for sister chromatid cohesion

(2011) Nenggang Zhang et al.   CELL CYCLE

Cohesin: a catenase with separate entry and exit gates?

(2011) Kim Nasmyth   NATURE CELL BIOLOGY

Sororin Mediates Sister Chromatid Cohesion by Antagonizing Wapl

(2010) Tomoko Nishiyama et al.   CELL

ATP Hydrolysis Is Required for Relocating Cohesin from Sites Occupied by Its Scc2/4 Loading Complex

(2010) Bin Hu et al.   CURRENT BIOLOGY

Lesson from the Stoichiometry Determination of the Cohesin Complex: A Short Protease Mediated Elution Increases the Recovery from Cross-Linked Antibody-Conjugated Beads

(2010) Johann Holzmann et al.   JOURNAL OF PROTEOME RESEARCH

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

(2010) Beate Neumann et al.   NATURE

Stoichiometry Determination of the MP1−p14 Complex Using a Novel and Cost-Efficient Method To Produce an Equimolar Mixture of Standard Peptides

(2009) Johann Holzmann et al.   ANALYTICAL CHEMISTRY

Cohesins Functionally Associate with CTCF on Mammalian Chromosome Arms

(2008) Vania Parelho et al.   CELL

A handcuff model for the cohesin complex

(2008) Nenggang Zhang et al.   JOURNAL OF CELL BIOLOGY

The cohesin ring concatenates sister DNA molecules

(2008) Christian H. Haering et al.   NATURE

Cohesin mediates transcriptional insulation by CCCTC-binding factor

(2008) Kerstin S. Wendt et al.   NATURE