Novel prodrugs of decitabine with greater metabolic stability and less toxicity

Establishment of a high-throughput detection system for DNA demethylating agents

(2018) Eriko Okochi-Takada et al.   Epigenetics

Genetic and epigenetic alterations in normal tissues have differential impacts on cancer risk among tissues

(2018) Satoshi Yamashita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MACON: a web tool for computing DNA methylation data obtained by the Illumina Infinium Human DNA methylation BeadArray

(2018) Naoko Iida et al.   Epigenomics

Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study

(2017) Robert Molokie et al.   PLOS MEDICINE

Transcriptional Selectivity of Epigenetic Therapy in Cancer

(2016) Takahiro Sato et al.   CANCER RESEARCH

Targeting the cancer epigenome for therapy

(2016) Peter A. Jones et al.   NATURE REVIEWS GENETICS

Establishment of a DNA methylation marker to evaluate cancer cell fraction in gastric cancer

(2015) Liang Zong et al.   Gastric Cancer

Pharmacokinetics of different formulations of oral azacitidine (CC-486) and the effect of food and modified gastric pH on pharmacokinetics in subjects with hematologic malignancies

(2013) Eric Laille et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Small-molecular modulators of cancer-associated epigenetic mechanisms

(2013) Yukihiro Itoh et al.   Molecular BioSystems

Differential Induction of Apoptosis and Senescence by the DNA Methyltransferase Inhibitors 5-Azacytidine and 5-Aza-2'-Deoxycytidine in Solid Tumor Cells

(2013) S. Venturelli et al.   MOLECULAR CANCER THERAPEUTICS

Delivery of 5-Azacytidine to Human Cancer Cells by Elaidic Acid Esterification Increases Therapeutic Drug Efficacy

(2010) B. Brueckner et al.   MOLECULAR CANCER THERAPEUTICS

S110, a 5-Aza-2'-Deoxycytidine-Containing Dinucleotide, Is an Effective DNA Methylation Inhibitor In vivo and Can Reduce Tumor Growth

(2010) J. C. Chuang et al.   MOLECULAR CANCER THERAPEUTICS

Targeting of 5-aza-2′-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme

(2010) Katan Patel et al.   NUCLEIC ACIDS RESEARCH

Epigenetics in cancer: Targeting chromatin modifications

(2009) L. Ellis et al.   MOLECULAR CANCER THERAPEUTICS

Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine

(2008) Carlo Stresemann et al.   INTERNATIONAL JOURNAL OF CANCER