Confounding of linkage disequilibrium patterns in large scale DNA based gene-gene interaction studies

Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection

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A roadmap to multifactor dimensionality reduction methods

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A cautionary note on the impact of protocol changes for genome-wide association SNP × SNP interaction studies: an example on ankylosing spondylitis

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Meta-analysis of the heritability of human traits based on fifty years of twin studies

(2015) Tinca J C Polderman et al.   NATURE GENETICS

Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1

(2015) Adrian Cortes et al.   Nature Communications

A survey about methods dedicated to epistasis detection

(2015) Clément Niel et al.   Frontiers in Genetics

Practical aspects of genome-wide association interaction analysis

(2014) Elena S. Gusareva et al.   HUMAN GENETICS

EpiSIM: simulation of multiple epistasis, linkage disequilibrium patterns and haplotype blocks for genome-wide interaction analysis

(2013) Junliang Shang et al.   Genes & Genomics

Long Range Linkage Disequilibrium across the Human Genome

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Gene-Based Testing of Interactions in Association Studies of Quantitative Traits

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An integrated map of genetic variation from 1,092 human genomes

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Lower-Order Effects Adjustment in Quantitative Traits Model-Based Multifactor Dimensionality Reduction

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HAPGEN2: simulation of multiple disease SNPs

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SNPPicker: High quality tag SNP selection across multiple populations

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Travelling the world of gene-gene interactions

(2011) K. Van Steen   BRIEFINGS IN BIOINFORMATICS

Novel measures of linkage disequilibrium that correct the bias due to population structure and relatedness

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Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

(2011) David M Evans et al.   NATURE GENETICS

The effects of linkage disequilibrium in large scale SNP datasets for MDR

(2011) Benjamin J Grady et al.   BioData Mining

BOOST: A Fast Approach to Detecting Gene-Gene Interactions in Genome-wide Case-Control Studies

(2010) Xiang Wan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Model-Based Multifactor Dimensionality Reduction for detecting epistasis in case-control data in the presence of noise

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EPIBLASTER-fast exhaustive two-locus epistasis detection strategy using graphical processing units

(2010) Tony Kam-Thong et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The Meaning of Interaction

(2010) Xuefeng Wang et al.   HUMAN HEREDITY

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

Variance component model to account for sample structure in genome-wide association studies

(2010) Hyun Min Kang et al.   NATURE GENETICS

FAM-MDR: A Flexible Family-Based Multifactor Dimensionality Reduction Technique to Detect Epistasis Using Related Individuals

(2010) Tom Cattaert et al.   PLoS One

Detecting gene–gene interactions that underlie human diseases

(2009) Heather J Cordell   NATURE REVIEWS GENETICS

Improving strategies for detecting genetic patterns of disease susceptibility in association studies

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