Reproduction disrupts stem cell homeostasis in testes of aged male Drosophila via an induced microenvironment

JNK signaling triggers spermatogonial dedifferentiation during chronic stress to maintain the germline stem cell pool in the Drosophila testis

(2018) Salvador C Herrera et al.   eLife

Soma-germ line interactions and a role for muscle in the regulation of C. elegans sperm motility

(2018) Daniela R. Chavez et al.   DEVELOPMENT

Drosophila intestinal stem and progenitor cells are major sources and regulators of homeostatic niche signals

(2018) David P. Doupé et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Germline Proliferation Is Regulated by Somatic Endocytic Genes via JNK and BMP Signaling inDrosophila

(2017) Yaning Tang et al.   GENETICS

Feedback amplification loop drives malignant growth in epithelial tissues

(2017) Mariana Muzzopappa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environmental stresses induce transgenerationally inheritable survival advantages via germline-to-soma communication in Caenorhabditis elegans

(2017) Saya Kishimoto et al.   Nature Communications

Germline Proliferation Is Regulated by Somatic Endocytic Genes via JNK and BMP Signaling inDrosophila

(2017) Yaning Tang et al.   GENETICS

Two different specific JNK activators are required to trigger apoptosis or compensatory proliferation in response to Rbf1 in Drosophila

(2016) Amandine Clavier et al.   CELL CYCLE

The Drosophila TNF Eiger Is an Adipokine that Acts on Insulin-Producing Cells to Mediate Nutrient Response

(2016) Neha Agrawal et al.   Cell Metabolism

Targeting theGdnfGene in peritubular myoid cells disrupts undifferentiated spermatogonial cell development

(2016) Liang-Yu Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A genome-wide resource for the analysis of protein localisation in Drosophila

(2016) Mihail Sarov et al.   eLife

A screen of apoptosis and senescence regulatory genes for life span effects when over-expressed in Drosophila

(2016) Jie Shen et al.   Aging-US

Aggression, mate guarding and fitness in male fruit flies

(2015) Carling M. Baxter et al.   ANIMAL BEHAVIOUR

The regulated elimination of transit-amplifying cells preserves tissue homeostasis during protein starvation in Drosophila testis

(2015) H. Yang et al.   DEVELOPMENT

A new level of plasticity:Drosophilasmooth-like testes muscles compensate failure of myoblast fusion

(2015) Jessica Kuckwa et al.   DEVELOPMENT

CSN maintains the germline cellular microenvironment and controls the level of stem cell genes via distinct CRLs in testes of Drosophila melanogaster

(2015) Yue Qian et al.   DEVELOPMENTAL BIOLOGY

The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth

(2015) Ditte S. Andersen et al.   NATURE

Haemocytes control stem cell activity in the Drosophila intestine

(2015) Arshad Ayyaz et al.   NATURE CELL BIOLOGY

Dual Role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation

(2014) Yongjie Wei et al.   Autophagy

Transformed Epithelia Trigger Non-Tissue-Autonomous Tumor Suppressor Response by Adipocytes via Activation of Toll and Eiger/TNF Signaling

(2014) Federica Parisi et al.   Cell Reports

Reproduction, Fat Metabolism, and Life Span: What Is the Connection?

(2013) Malene Hansen et al.   Cell Metabolism

Smurf-mediated differential proteolysis generates dynamic BMP signaling in germline stem cells during Drosophila testis development

(2013) Yi-Jie Chang et al.   DEVELOPMENTAL BIOLOGY

The genetic depletion or the triptolide inhibition of TFIIH in p53-deficient cells induces a JNK-dependent cell death in Drosophila

(2013) C. Villicana et al.   JOURNAL OF CELL SCIENCE

Proneural proteins Achaete and Scute associate with nuclear actin to promote formation of external sensory organs

(2013) Y.-L. Hsiao et al.   JOURNAL OF CELL SCIENCE

DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance

(2013) Maria A. Ermolaeva et al.   NATURE

Human testicular peritubular cells: more than meets the eye

(2013) Artur Mayerhofer   REPRODUCTION

Hedgehog is required for CySC self-renewal but does not contribute to the GSC niche in the Drosophila testis

(2012) M. Amoyel et al.   DEVELOPMENT

Multinucleated smooth muscles and mononucleated as well as multinucleated striated muscles develop during establishment of the male reproductive organs of Drosophila melanogaster

(2012) Loreen Susic-Jung et al.   DEVELOPMENTAL BIOLOGY

GAL4 enhancer traps that can be used to drive gene expression in developingDrosophilaspermatocytes

(2012) Stephanie M. Bunt et al.   GENESIS

KAYAK-  Modulates Circadian Transcriptional Feedback Loops in Drosophila Pacemaker Neurons

(2012) J. Ling et al.   JOURNAL OF NEUROSCIENCE

The let-7–Imp axis regulates ageing of the Drosophila testis stem-cell niche

(2012) Hila Toledano et al.   NATURE

The Germline Stem Cell Niche Unit in Mammalian Testes

(2012) Jon M. Oatley et al.   PHYSIOLOGICAL REVIEWS

A Versatile ΦC31 Based Reporter System for Measuring AP-1 and Nrf2 Signaling in Drosophila and in Tissue Culture

(2012) Nirmalya Chatterjee et al.   PLoS One

Somatic cell lineage is required for differentiation and not maintenance of germline stem cells in Drosophila testes

(2012) J. G. Y. Lim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

dJun and Vri/dNFIL3 Are Major Regulators of Cardiac Aging in Drosophila

(2012) Véronique Monnier et al.   PLoS Genetics

Asymmetric division of cyst stem cells in Drosophila testis is ensured by anaphase spindle repositioning

(2011) J. Cheng et al.   DEVELOPMENT

The stem cell niche: lessons from the Drosophila testis

(2011) M. de Cuevas et al.   DEVELOPMENT

String (Cdc25) regulates stem cell maintenance, proliferation and aging in Drosophila testis

(2011) M. Inaba et al.   DEVELOPMENT

Glial-Derived Prodegenerative Signaling in the Drosophila Neuromuscular System

(2011) Lani C. Keller et al.   NEURON

chinmo Is a Functional Effector of the JAK/STAT Pathway that Regulates Eye Development, Tumor Formation, and Stem Cell Self-Renewal in Drosophila

(2010) Maria Sol Flaherty et al.   DEVELOPMENTAL CELL

Rho1 regulates apoptosis via activation of the JNK signaling pathway at the plasma membrane

(2010) Amanda L. Neisch et al.   JOURNAL OF CELL BIOLOGY

The Drosophila TNF Ortholog Eiger Is Required in the Fat Body for a Robust Immune Response

(2010) Eric M. Mabery et al.   Journal of Innate Immunity

Insights into aging through measurements of the Drosophila proteome as a function of temperature

(2010) Renã A.S. Robinson et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Germline self-renewal requires cyst stem cells and stat regulates niche adhesion in Drosophila testes

(2010) Judith L. Leatherman et al.   NATURE CELL BIOLOGY

BMP and Hh Signaling Affects Primordial Germ Cell Division inDrosophila

(2010) Takuya Sato et al.   ZOOLOGICAL SCIENCE

Lifespan Extension by Preserving Proliferative Homeostasis in Drosophila

(2010) Benoît Biteau et al.   PLoS Genetics

Trade-off between age of first reproduction and survival in a female primate

(2009) G. E. Blomquist   Biology Letters

Drosophila Maelstrom Ensures Proper Germline Stem Cell Lineage Differentiation by Repressing microRNA-7

(2009) Jun Wei Pek et al.   DEVELOPMENTAL CELL

Intrinsic Tumor Suppression and Epithelial Maintenance by Endocytic Activation of Eiger/TNF Signaling in Drosophila

(2009) Tatsushi Igaki et al.   DEVELOPMENTAL CELL

Accumulation of a differentiation regulator specifies transit amplifying division number in an adult stem cell lineage

(2009) Megan L. Insco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of Metabolic Homeostasis by Stress Signaling Is Mediated by the Lipocalin NLaz

(2009) Julie Hull-Thompson et al.   PLoS Genetics

Reproductive Senescence in a Long‐Lived Seabird: Rates of Decline in Late‐Life Performance Are Associated with Varying Costs of Early Reproduction

(2008) Thomas E. Reed et al.   AMERICAN NATURALIST

Zfh-1 Controls Somatic Stem Cell Self-Renewal in the Drosophila Testis and Nonautonomously Influences Germline Stem Cell Self-Renewal

(2008) Judith L. Leatherman et al.   Cell Stem Cell

JNK Activity in Somatic Stem Cells Causes Loss of Tissue Homeostasis in the Aging Drosophila Gut

(2008) Benoît Biteau et al.   Cell Stem Cell

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

(2008) Yongjie Wei et al.   MOLECULAR CELL

Centrosome misorientation reduces stem cell division during ageing

(2008) Jun Cheng et al.   NATURE