Mathematical model predicts anti-adhesion–antibiotic–debridement combination therapies can clear an antibiotic resistant infection

Evaluation of Meropenem Pharmacokinetics in an Experimental Acute Respiratory Distress Syndrome (ARDS) Model during Extracorporeal Membrane Oxygenation (ECMO) by Using a PenP β-Lactamase Biosensor

(2018) Max Andresen et al.   SENSORS

Predictive modelling of a novel anti-adhesion therapy to combat bacterial colonisation of burn wounds

(2018) Paul A. Roberts et al.   PLoS Computational Biology

Source–sink plasmid transfer dynamics maintain gene mobility in soil bacterial communities

(2016) James P. J. Hall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenotypic Heterogeneity and the Evolution of Bacterial Life Cycles

(2016) Jordi van Gestel et al.   PLoS Computational Biology

Targeting bacterial adherence inhibits multidrug-resistant Pseudomonas aeruginosa infection following burn injury

(2016) Ryan M. Huebinger et al.   Scientific Reports

Bacterial fitness shapes the population dynamics of antibiotic-resistant and -susceptible bacteria in a model of combined antibiotic and anti-virulence treatment

(2015) Lucy Ternent et al.   JOURNAL OF THEORETICAL BIOLOGY

Potential burden of antibiotic resistance on surgery and cancer chemotherapy antibiotic prophylaxis in the USA: a literature review and modelling study

(2015) Aude Teillant et al.   LANCET INFECTIOUS DISEASES

Bacteriophages Limit the Existence Conditions for Conjugative Plasmids

(2015) Ellie Harrison et al.   mBio

Dosing regimen of meropenem for adults with severe burns: a population pharmacokinetic study with Monte Carlo simulations

(2014) A. Ramon-Lopez et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Targeting virulence: can we make evolution-proof drugs?

(2014) Richard C. Allen et al.   NATURE REVIEWS MICROBIOLOGY

Gram Negative Wound Infection in Hospitalised Adult Burn Patients-Systematic Review and Metanalysis-

(2014) Ernest A. Azzopardi et al.   PLoS One

Limiting Damage during Infection: Lessons from Infection Tolerance for Novel Therapeutics

(2014) Pedro F. Vale et al.   PLOS BIOLOGY

Nosocomial infection characteristics in a burn intensive care unit: Analysis of an eleven-year active surveillance

(2013) Oral Öncül et al.   BURNS

Prostatic penetration of meropenem in humans, and dosage considerations for prostatitis based on a site-specific pharmacokinetic/pharmacodynamic evaluation

(2013) Genya Nishikawa et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Concepts in disinfection of bacterial populations

(2013) N.G. Cogan   MATHEMATICAL BIOSCIENCES

A MAM7 Peptide-Based Inhibitor of Staphylococcus aureus Adhesion Does Not Interfere with In Vitro Host Cell Function

(2013) Catherine Alice Hawley et al.   PLoS One

Direct observation of single stationary-phase bacteria reveals a surprisingly long period of constant protein production activity

(2013) O. Gefen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting the bacteria–host interface

(2013) Anne Marie Krachler et al.   Virulence

Wound healing modeling: investigating ambient gas plasma treatment efficacy

(2012) Marat Orazov et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

Turnabout is fair play

(2012) Anne Marie Krachler et al.   Virulence

In vitro characterization of multivalent adhesion molecule 7-based inhibition of multidrug-resistant bacteria isolated from wounded military personnel

(2012) Anne Marie Krachler et al.   Virulence

Cross-Strain Quorum Sensing Inhibition by Staphylococcus aureus. Part 1: A Spatially Homogeneous Model

(2011) Sara Jabbari et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Cross-Strain Quorum Sensing Inhibition by Staphylococcus Aureus. Part 2: A Spatially Inhomogeneous Model

(2011) Sara Jabbari et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Pharmacodynamics of meropenem in critically ill patients with febrile neutropenia and bacteraemia

(2011) Sutep Jaruratanasirikul et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Functional Characterization of the Interaction between Bacterial Adhesin Multivalent Adhesion Molecule 7 (MAM7) Protein and Its Host Cell Ligands

(2011) Anne Marie Krachler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tackling antibiotic resistance

(2011) Karen Bush et al.   NATURE REVIEWS MICROBIOLOGY

Outer membrane adhesion factor multivalent adhesion molecule 7 initiates host cell binding during infection by Gram-negative pathogens

(2011) A. M. Krachler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A mathematical investigation of the effects of inhibitor therapy on three putative phosphorylation cascades governing the two-component system of the agr operon

(2010) Sara Jabbari et al.   MATHEMATICAL BIOSCIENCES

Anti-virulence strategies to combat bacteria-mediated disease

(2010) David A. Rasko et al.   NATURE REVIEWS DRUG DISCOVERY

The Effect of Bacteria on Epidermal Wound Healing

(2010) E. Agyingi et al.   Mathematical Modelling of Natural Phenomena

Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution

(2009) Jason A. Roberts et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Cell division in Escherichia coli cultures monitored at single cell resolution

(2008) Johanna Roostalu et al.   BMC MICROBIOLOGY

Review of the guidelines for complicated skin and soft tissue infections and intra-abdominal infections—are they applicable today?

(2008) M. Caínzos   CLINICAL MICROBIOLOGY AND INFECTION

Exploring the role of the immune response in preventing antibiotic resistance

(2008) Andreas Handel et al.   JOURNAL OF THEORETICAL BIOLOGY