Journal
MATERIALS EXPRESS
Volume 9, Issue 4, Pages 319-327Publisher
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/mex.2019.1499
Keywords
Photoelectrochemical Aptasensor; Cytochrome c; TiO2 Nanotube; Au NPs; CdS
Funding
- National Science Foundation of China [21874038]
Ask authors/readers for more resources
A novel photoelectrode of ternary CdS/Au/TiO2 nanotube array, fabricated by electrodeposition technique and successive ionic layer adsorption and reaction (SILAR) method, shows strong photon absorption capacity and active charge transfer efficiency. A photoelectrochemical aptasensor was developed to detect cytochrome c (cyt c) by decorating a HS-aptamer on the CdS/Au/TiO2 photoelectrode. Due to the specific binding between the cyt c and aptamer, the cyt c-aptamer complex formed and enhanced the steric hindrances and reduced the elh(+)lifetimes, which result in a decrease in the photoelectrical current intensity. Cyt c is, therefore, also quantified based on the decrease in photoelectrical current. The developed aptasensor shows a high specificity and a high sensitivity towards to the cyt c, giving a linear range from 5 pM to 100 nM, and a limit of detection of 3.45 pM.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available