Exposure-response analysis of drug-induced QT interval prolongation in telemetered monkeys for translational prediction to human

Published 2019 View Full Article

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Title
Exposure-response analysis of drug-induced QT interval prolongation in telemetered monkeys for translational prediction to human
Authors
Keywords
Cynomolgus monkey, Exposure-response analysis, J-ICET, Methods, Preclinical-clinical concordance, Probabilistic QT analysis, QT interval prolongation, QT rate-correction, Safety pharmacology, Telemetry
Journal
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
Volume -, Issue -, Pages 106606
Publisher
Elsevier BV
Online
2019-06-28
DOI
10.1016/j.vascn.2019.106606

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