Metformin targeting autophagy overcomes progesterone resistance in endometrial carcinoma

Metformin impairs growth of endometrial cancer cells via cell cycle arrest and concomitant autophagy and apoptosis

(2014) Akimasa Takahashi et al.   Cancer Cell International

Metformin Plays a Dual Role in MIN6 Pancreatic β Cell Function through AMPK-dependent Autophagy

(2014) Yingling Jiang et al.   International Journal of Biological Sciences

Management of Type 2 Diabetes — Polling Results

(2014) Joann M. Schulte et al.   NEW ENGLAND JOURNAL OF MEDICINE

Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling

(2014) Y Feng et al.   Cell Death & Disease

Combination of Diane-35 and Metformin to Treat Early Endometrial Carcinoma in PCOS Women with Insulin Resistance

(2014) Xin Li et al.   Journal of Cancer

Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1

(2013) Gnanapragasam Arunachalam et al.   BRITISH JOURNAL OF PHARMACOLOGY

Progesterone Action in Endometrial Cancer, Endometriosis, Uterine Fibroids, and Breast Cancer

(2013) J. Julie Kim et al.   ENDOCRINE REVIEWS

Metformin potentiates the effects of paclitaxel in endometrial cancer cells through inhibition of cell proliferation and modulation of the mTOR pathway

(2012) Rabbie K. Hanna et al.   GYNECOLOGIC ONCOLOGY

Thiazolidinediones and metformin associated with improved survival of diabetic prostate cancer patients

(2011) X.- X. He et al.   ANNALS OF ONCOLOGY

Molecular pathogenesis of cervical cancer

(2011) Okechukwu A. Ibeanu   CANCER BIOLOGY & THERAPY

The dynamic nature of autophagy in cancer

(2011) A. C. Kimmelman   GENES & DEVELOPMENT

Progesterone: the ultimate endometrial tumor suppressor

(2011) Shujie Yang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Autophagy in endometrial carcinomas and prognostic relevance of 'stone-like' structures (SLS): What is destined for the atypical endometrial hyperplasia?

(2010) Efthimios Sivridis et al.   Autophagy

AMPK: Evidence for an energy-sensing cytokinetic tumor suppressor

(2010) Alejandro Vazquez-Martin et al.   CELL CYCLE

Long-Term Metformin Use Is Associated With Decreased Risk of Breast Cancer

(2010) M. Bodmer et al.   DIABETES CARE

Metformin in Cancer Therapy: A New Perspective for an Old Antidiabetic Drug?

(2010) I. Ben Sahra et al.   MOLECULAR CANCER THERAPEUTICS

Role of Progesterone in Endometrial Cancer

(2010) J. Kim et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Reduced expression of DRAM2/TMEM77 in tumor cells interferes with cell death

(2009) Sun-Mi Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Metformin use and prostate cancer in Caucasian men: results from a population-based case–control study

(2009) Jonathan L. Wright et al.   CANCER CAUSES & CONTROL

The influence of glucose-lowering therapies on cancer risk in type 2 diabetes

(2009) C. J. Currie et al.   DIABETOLOGIA

Antidiabetic Therapies Affect Risk of Pancreatic Cancer

(2009) Donghui Li et al.   GASTROENTEROLOGY

Metformin is a potent inhibitor of endometrial cancer cell proliferation—implications for a novel treatment strategy

(2009) Leigh A. Cantrell et al.   GYNECOLOGIC ONCOLOGY

The Effects of Adiponectin and Metformin on Prostate and Colon Neoplasia Involve Activation of AMP-Activated Protein Kinase

(2008) M. Zakikhani et al.   Cancer Prevention Research