Article
Gastroenterology & Hepatology
Daisuke Mizushima, Misao Takano, Takahiro Aoki, Naokatsu Ando, Haruka Uemura, Yasuaki Yanagawa, Koji Watanabe, Hiroyuki Gatanaga, Yoshimi Kikuchi, Shinichi Oka
Summary: The study evaluated the incidence of HBV infection among MSM and the effectiveness of tenofovir-based PrEP in preventing HBV infection. The results showed that the use of PrEP significantly reduced the rate of HBV infection among MSM, but individuals using PrEP were more susceptible to other sexually transmitted infections. A separate study on MSM with HBsAb-positive and HBcAb-negative status found an HBV incidence rate of 1.8% among PrEP users. In conclusion, tenofovir-based PrEP is effective in preventing HBV infection among MSM.
Article
Multidisciplinary Sciences
Jiaqi Fu, Zhenwei Dai, Hao Wang, Mingyu Si, Xu Chen, Yijin Wu, Weijun Xiao, Yiman Huang, Fei Yu, Guodong Mi, Xiaoyou Su
Summary: This study explores the willingness to use long-acting injectable-pre-exposure prophylaxis (LAI-PrEP) among men who have sex with men (MSM) in China. The study found that MSM had high awareness but low uptake of PrEP. The results highlight the need for education programs focused on PrEP and healthy sexual behavior, and provide evidence for future LAI-PrEP use among the Chinese MSM population.
Article
Health Care Sciences & Services
Bing Lin, Jiaxiu Liu, Wei He, Haiying Pan, Yingjie Ma, Xiaoni Zhong
Summary: This study explores the effect of a reminder system based on the WeChat social media app on PrEP adherence in MSM. The results indicate that the reminder system is significantly effective in improving adherence in the early stage, motivating users and facilitating the development of healthy medicine-taking habits.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Brooke G. Rogers, P. A. Chan, C. Sutten-Coats, A. Zanowick-Marr, R. R. Patel, L. Mena, W. C. Goedel, C. Chu, E. Silva, D. Galipeau, T. Arnold, C. Gomillia, K. Curoe, J. Villalobos, A. Underwood, C. Sosnowy, Amy S. Nunn
Summary: This study examined the perspectives of 49 men who have sex with men (MSM) on long-acting formulations of PrEP. The findings suggest that although participants were not very knowledgeable about long-acting PrEP, they were open to learning about and considering these options. Safety, efficacy, and reducing clinic visits were identified as important factors in their decision-making process.
Article
Multidisciplinary Sciences
Francesc Lopez Segui, Unai Oyon Lerga, Laura Laguna Marmol, Pep Coll, Angels Andreu, Michael Meulbroek, Guillem Lopez Casasnovas, Oriol Estrada Cuxart, Jordi Ara Rey, Carles Quinones, Felix Perez, Javier Fernandez, Angel Rivero, Laura Ricou Rios, Bonaventura Clotet
Summary: The study evaluates the cost-effectiveness of implementing HIV pre-exposure prophylaxis in Catalonia. The results show that daily oral PrEP can save costs and generate health and monetary benefits in the long term.
Article
Public, Environmental & Occupational Health
Dora Arnold-Forster, Robert Horne, Will Nutland, Sonali Wayal, Michael Rayment, Caroline Rae, Monica Desai, Amanda Clarke, Ann Sullivan, Sheena McCormack, Mitzy Gafos
Summary: Using the perceptions and practicalities approach (PAPA) can help identify factors that influence PrEP adherence and tailor adherence support in PrEP programs.
Article
Health Policy & Services
Mor Zohar, Shilo Guy, Levy Itzchak
Summary: This study found high PrEP awareness among MSM in Israel, with 44.8% willing to take PrEP, especially those engaged in high-risk sexual behaviors. Willingness to use PrEP increased with potential efficacy of the drug and decreased with cost.
ISRAEL JOURNAL OF HEALTH POLICY RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
Yuanqi Mi, Yuhong Zeng, Peicheng Wang, Mengge Zhou, Feng Cheng
Summary: This review assessed the cost-effectiveness of pre-exposure prophylaxis implementation among men who have sex with men in China. The findings suggest that pre-exposure prophylaxis is only cost-effective when the market price is reduced by at least 5.5%. The study calls for more standardized and transparent modeling studies that consider the latest drug types and market prices.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Health Care Sciences & Services
David Gillespie, Fiona Wood, Adam Williams, Richard Ma, Marijn de Bruin, Dyfrig A. Hughes, Adam T. Jones, Zoe Couzens, Kerenza Hood
Summary: This study aimed to investigate the experiences of men who have sex with men (MSM) living in Wales in initiating, implementing, and persisting with HIV Pre-exposure Prophylaxis (PrEP). Findings revealed that drivers for discontinuation of PrEP included habitual behavior and engagement with sexual health services, while stigma surrounding PrEP and HIV acted as a driver for initiating PrEP.
HEALTH EXPECTATIONS
(2022)
Article
Infectious Diseases
Brooke G. Rogers, C. Sosnowy, A. Zanowick-Marr, P. A. Chan, L. A. Mena, R. R. Patel, W. C. Goedel, T. Arnold, C. Chu, D. Galipeau, M. C. Montgomery, K. Curoe, A. Underwood, J. Villalobos, C. Gomillia, A. S. Nunn
Summary: This study conducted interviews with men who have sex with men in three regions of the U.S. and identified multiple factors that promote PrEP persistence, including structural, social, clinical, and behavioral factors. The results suggest that providing navigation to reduce PrEP costs, establishing social norms that support PrEP use, providing LGBTQ+ affirming medical services, incorporating medication into daily routines, and facilitating sexual health agency can improve PrEP persistence.
BMC INFECTIOUS DISEASES
(2022)
Article
Multidisciplinary Sciences
Ashwin Belludi, Allison M. McFall, Sunil Suhas Solomon, David D. Celentano, Shruti H. Mehta, A. K. Srikrishnan, M. Suresh Kumar, Suniti Solomon, Gregory M. Lucas
Summary: The study in India revealed low awareness but high willingness to use PrEP among PWID and MSM. Common reasons for unwillingness to use PrEP included perceived low risk of HIV infection, fear of being labeled as HIV-positive, and concerns about side effects. Key factors associated with increased willingness to use PrEP included sharing needles and hazardous alcohol use among PWID, and having a main male partner and injection drug use among MSM.
Article
Health Care Sciences & Services
Yi-Fang Yu, Huei-Jiuan Wu, Stephane Wen-Wei Ku, Po-Hsien Huang, Chia-Wen Li, Poyao Huang, Carol Strong
Summary: Using latent class analysis, this study identified three different profiles of sex events and PrEP use among men who have sex with men. The study found that increasing PrEP adherence and incorporating condom use is necessary to reduce the risk of condomless anal sex. The findings highlight the importance of flexible HIV prevention strategies that combine PrEP with condom use.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Health Care Sciences & Services
Wipaporn Natalie Songtaweesin, Sara LeGrand, Shashika Bandara, Caitlin Piccone, Prissana Wongharn, Juthamanee Moonwong, Thidarat Jupimai, Chutima Saisaengjan, Tuangtip Theerawit, Kathryn Muessig, Lisa Hightow-Weidman, Thanyawee Puthanakit, Nittaya Phanuphak, Arunrat Tangmunkongvorakul
Summary: HIV disproportionately affects young Thai men who have sex with men, and adapting the P3 app developed in the United States to the Thai context for PrEP adherence among YMSM is necessary. Implementing minor modifications in terms of aesthetics and presentation of information was crucial to customize the app effectively. Ultimately, collaborations with local app designers and developers are important for a successful adaptation process.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Immunology
Gordon Mansergh, Krishna Kiran Kota, Rob Stephenson, Sabina Hirshfield, Patrick Sullivan
Summary: Most men who have sex with men showed interest in using various potential HIV prevention products, especially long-acting injectables (LAIs). Participants could be classified into two typologies: those who prefer sexual event-based methods and those who prefer non-sexual event-based methods. Men reporting recent unprotected anal sex preferred penile gel products the most.
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY
(2021)
Article
Immunology
Christina Chandra, Kevin M. Weiss, Colleen F. Kelley, Julia L. Marcus, Samuel M. Jenness
Summary: The study found substantial gaps between CDC recommendations for STI screening during PrEP care and current clinical practice, particularly for MSM in the Southeast states, where screening for urogenital and rectal STIs was significantly less likely to be consistent compared to other regions.
CLINICAL INFECTIOUS DISEASES
(2021)
Letter
Gastroenterology & Hepatology
Shengzhi Sun, Qingqing Yang, Qingxin Zhou, Wangnan Cao, Siwang Yu, Siyan Zhan, Feng Sun
Review
Medicine, General & Internal
Ethan M. Balk, Gaelen P. Adam, Wangnan Cao, Shivani Mehta, Nishit Shah
Summary: The value of interventions used after acute colonic diverticulitis is unclear. Colonoscopy does not reduce the risk of long-term colorectal cancer diagnosis. Mesalamine is ineffective in preventing recurrence. Elective surgery reduces recurrence in patients with prior complicated or smoldering or frequently recurrent diverticulitis, but it is unclear which of these patients may benefit most.
ANNALS OF INTERNAL MEDICINE
(2022)
Article
Health Care Sciences & Services
Xiaoyan Fan, Ke Ning, Cong Liu, Haidan Zhong, Joseph T. F. Lau, Chun Hao, Yuantao Hao, Jinghua Li, Linghua Li, Jing Gu
Summary: Men who have sex with men (MSM) in China face a disproportionate HIV epidemic and have suboptimal medication adherence. An app-based case management service was developed to address this issue, with components including web-based communication, educational articles, supportive service information, and hospital visit reminders. The intervention was well-received, and delivering educational resources of interest may enhance medication adherence.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Health Care Sciences & Services
Ju-Shuang Li, Yu-Zhou Gu, Feng-Su Hou, Yong-Heng Lu, Xiao-Ru Fan, Jia-Ling Qiu, Qing-Ling Yang, Jing Gu, Jing-Hua Li, Dong Roman Xu, Chun Hao
Summary: This study explores the effectiveness and associated factors of a recruitment strategy using WeChat-based HIV e-report exchange in social networks among MSM. The results show that using e-report for recruitment is feasible, and the success of online recruitment depends on the familiarity of MSM with the digital tool.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Substance Abuse
Xiaochen Yang, Lanchao Zhang, Hao Lin, Haoxiang Lin, Wangnan Cao, Chun Chang
Summary: This study explores the relationship between depressive/anxiety symptoms and the intention to quit smoking, and the factors that influence this relationship. The findings indicate that psychiatric symptoms are significant factors in reducing the willingness of smokers to quit smoking, and these effects are moderated by smokers' cigarette consumption conditions.
TOBACCO INDUCED DISEASES
(2023)
Article
Health Care Sciences & Services
Hai-Tong Sun, Xiao-Ru Fan, Yu-Zhou Gu, Yong-Heng Lu, Jia-Ling Qiu, Qing-Ling Yang, Jing-Hua Li, Jing Gu, Chun Hao
Summary: This study investigated the use of HIV e-report as a new approach for HIV serostatus request and disclosure among MSM in Guangzhou, China. The findings suggest that the HIV e-report has been accepted and could be effective in promoting infectious disease serostatus disclosure among the high-risk population.
JMIR MHEALTH AND UHEALTH
(2023)
Correction
Health Care Sciences & Services
Hai -Tong Sun, Xiao-Ru Fan, Yu -Zhou Gu, Yong-Heng Lu, Jia-Ling Qiu, Qing-Ling Yang, Jing-Hua Li, Jing Gu, Chun Hao
JMIR MHEALTH AND UHEALTH
(2023)
Article
Health Care Sciences & Services
Yuqi Cai, Yuan Zhang, Wangnan Cao, Vivian Yawei Guo, Yang Deng, Liying Luo, Jianling Shen, Yang Zhu, Xiaoting Chen, Xiao Yang, Fengsu Hou, Jinghua Li
Summary: This study validated the Chinese version of the Revised Illness Perception Questionnaire for patients with Nasopharyngeal carcinoma, demonstrating its reliability, factorial validity, and construct validity. The questionnaire can be used to assess the illness perceptions of Chinese patients with nasopharyngeal carcinoma.
Article
Medicine, General & Internal
Sayuri Fujita-Imazu, Jinzhao Xie, Bibha Dhungel, Xinran Wang, Yijing Wang, Phuong Nguyen, July Khin Maung Soe, Jinghua Li, Stuart Gilmour
Summary: The number of accidental drug overdose deaths in the USA has increased significantly in the past two decades, with a four-fold increase in age-standardized mortality rates. There has been a shifting burden of drug overdose mortality to younger Americans, particularly those born after 1990, and the highest mortality risk is found in Black Americans and those born after 1975. Urgent action is needed to prevent preventable deaths among a new generation of Americans.
Article
Health Care Sciences & Services
Dong-Hua Luo, Xiao-Yun Li, Shan -Shan Guo, Wan -Ping Guo, Li -Ting Liu, Hao-Yuan Mo, Ling Guo, Xiao-Fei Lv, Li-Zhi Liu, Ji-Bin Li, Qing Liu, Pan Wang, Xue-Song Sun, Sai-Lan Liu, Qiu-Yan Chen, Lin-Quan Tang, Hai-Qiang Mai
Summary: The study demonstrated the efficacy and safety of the TPF regimen followed by de-escalated radiotherapy with concurrent cisplatin in treating childhood stage IVa-b NPC patients.
LANCET REGIONAL HEALTH-WESTERN PACIFIC
(2023)
Article
Health Care Sciences & Services
Xinwei Peng, Jibin Li, Yuwan Wu, Hongji Dai, Henry S. Lynn, Xi Zhang
Summary: This study aimed to evaluate the individual and joint associations of stool frequency and consistency with all-cause and cause-specific mortality. The results showed that less than 7 times/week of stool frequency is a significant risk factor for mortality. Additionally, irregular soft stools are associated with increased risks of all-cause, cancer, and cardiovascular disease mortality, emphasizing the importance of bowel health.
Article
Biochemistry & Molecular Biology
Tian-Qi Zhang, Zhi-Jun Geng, Meng-Xuan Zuo, Ji-Bin Li, Jin-Hua Huang, Zi-Lin Huang, Pei-Hong Wu, Yang-Kui Gu
Summary: The combination of camrelizumab, apatinib, and HAIC-FOLFOX demonstrated promising results and manageable safety concerns for HCC patients at BCLC stage C.
SIGNAL TRANSDUCTION AND TARGETED THERAPY
(2023)
Article
Health Care Sciences & Services
Yang Zhu, Xiaohui Wang, Xinyi You, Hongmei Zhao, Yawei Guo, Wangnan Cao, Meiqi Xin, Jinghua Li
Summary: This study aimed to quantify eHealth literacy and determine a cut-off value for eHEALS scores indicating adequate eHealth literacy among rural residents in Gansu, China. The findings revealed that eHealth literacy among rural residents in Gansu remains low, with an average score of 25.85. The study identified a cut-off value of 29.5 for eHEALS scores that signifies sufficient eHealth literacy within this demographic.
Article
Oncology
Xiao-Yun Li, Dong-Hua Luo, Ling Guo, Hao-Yuan Mo, Rui Sun, Shan-Shan Guo, Li-Ting Liu, Zhen-Chong Yang, Jin-Hao Yang, Fang Qiu, Xue-Song Sun, Pan Wang, Qing Liu, Ji-Bin Li, Qing-Nan Tang, Chao Lin, Qi Yang, Sai-Lan Liu, Yu-Jing Liang, Guo-Dong Jia, Dong-Xiang Wen, Chun-Yan Guo, Jin-Jie Yan, Chong Zhao, Qiu-Yan Chen, Lin-Quan Tang, Hai-Qiang Mai
Summary: The study compared the efficacy of two-cycle and three-cycle cisplatin-based chemoradiotherapy in patients with low-risk locally advanced nasopharyngeal carcinoma, showing that the two-cycle treatment was noninferior to the three-cycle treatment in terms of 3-year progression-free survival. However, the three-cycle group experienced more severe toxicities.
JOURNAL OF CLINICAL ONCOLOGY
(2022)
Article
Oncology
Ji-Bin Li, Zhi-Yu Qiu, Yu-Xiang Deng, Yin Li, Zhuo-Chen Lin, Yan-Ping Wu, Fan Weng, Huan Tian, Qing-Jian Ou, Cheng-Hua Gong, Zhi-Zhong Pan, De-Sen Wan, Jian-Hong Peng, Yu-Jing Fang
Summary: This study aimed to explore independent factors associated with the positive predictive value (PPV) of colonoscopy. The results showed that combining HRFQ and FIT could significantly improve the PPV for screening advanced neoplasm and colorectal cancer. Males, elders (>60 years), and current/ex-smokers had higher odds of detecting colorectal neoplasms.
