Anti-apoptotic activity of ETB receptor agonist, IRL-1620, protects neural cells in rats with cerebral ischemia

Endothelin Receptors, Mitochondria and Neurogenesis in Cerebral Ischemia

(2016) Anil Gulati   Current Neuropharmacology

Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane

(2016) Katelyn L. O'Neill et al.   GENES & DEVELOPMENT

Selective cerebral perfusion prevents abnormalities in glutamate cycling and neuronal apoptosis in a model of infant deep hypothermic circulatory arrest and reperfusion

(2016) Masaki Kajimoto et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Understanding neurogenesis in the adult human brain

(2015) Anil Gulati   INDIAN JOURNAL OF PHARMACOLOGY

Stimulation of endothelin B receptors by IRL-1620 decreases the progression of Alzheimer’s disease

(2015) S. Briyal et al.   NEUROSCIENCE

Animal models of ischemic stroke and their application in clinical research

(2015) Christoph Kleinschnitz et al.   Drug Design Development and Therapy

Endothelial Nitric-oxide Synthase (eNOS) Is Activated through G-protein-coupled Receptor Kinase-interacting Protein 1 (GIT1) Tyrosine Phosphorylation and Src Protein

(2014) Songling Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacokinetics of SPI-1620 in a Phase I, open label, ascending dose study of the safety, tolerability, pharmacokinetics and pharmacodynamics of the endothelin B receptor agonist, SPI-1620, in recurrent or progressive carcinoma

(2014) Guru Reddy et al.   LIFE SCIENCES

Neuroprotective and anti-apoptotic effects of liraglutide in the rat brain following focal cerebral ischemia

(2014) S. Briyal et al.   NEUROSCIENCE

Targeting the mitochondrial apoptotic pathway: a preferred approach in hematologic malignancies?

(2014) K Brinkmann et al.   Cell Death & Disease

Endothelin B receptor agonist, IRL-1620, enhances angiogenesis and neurogenesis following cerebral ischemia in rats

(2013) Mary G. Leonard et al.   BRAIN RESEARCH

Endothelin B receptor agonist, IRL-1620, provides long-term neuroprotection in cerebral ischemia in rats

(2012) Mary G. Leonard et al.   BRAIN RESEARCH

Endothelin B receptor agonist, IRL-1620, reduces neurological damage following permanent middle cerebral artery occlusion in rats

(2011) Mary G. Leonard et al.   BRAIN RESEARCH

Endothelinergic cells in the subependymal region of mice

(2010) Mauricio M. Castañeda et al.   BRAIN RESEARCH

Correlation of locomotor activity and brain infarction in rats with transient focal ischemia

(2009) Hui Shen et al.   JOURNAL OF NEUROSCIENCE METHODS

Apoptotic Mechanisms After Cerebral Ischemia

(2009) Brad R.S. Broughton et al.   STROKE

Deficiency in Endothelin Receptor B Reduces Proliferation of Neuronal Progenitors and Increases Apoptosis in Postnatal Rat Cerebellum

(2008) Maria Vidovic et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY