Rational drug-design approach supported with thermodynamic studies — a peptide leader for the efficient bi-substrate inhibitor of protein kinase CK2

Kinase-targeted cancer therapies: progress, challenges and future directions

(2018) Khushwant S. Bhullar et al.   Molecular Cancer

ITC-derived binding affinity may be biased due to titrant (nano)-aggregation. Binding of halogenated benzotriazoles to the catalytic domain of human protein kinase CK2

(2017) Maria Winiewska et al.   PLoS One

Thermodynamic parameters for binding of some halogenated inhibitors of human protein kinase CK2

(2015) Maria Winiewska et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Design, validation and efficacy of bisubstrate inhibitors specifically affecting ecto-CK2 kinase activity

(2015) G. Cozza et al.   BIOCHEMICAL JOURNAL

Thermodynamics parameters for binding of halogenated benzotriazole inhibitors of human protein kinase CK2α

(2015) Maria Winiewska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Acetoxymethyl Ester of Tetrabromobenzimidazole–Peptoid Conjugate for Inhibition of Protein Kinase CK2 in Living Cells

(2015) Kaido Viht et al.   BIOCONJUGATE CHEMISTRY

Selective Bisubstrate Inhibitors with Sub-nanomolar Affinity for Protein Kinase Pim-1

(2013) Ramesh Ekambaram et al.   ChemMedChem

A subnanomolar fluorescent probe for protein kinase CK2 interaction studies

(2012) Erki Enkvist et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Isomeric Mono-, Di-, and Tri-Bromobenzo-1H-Triazoles as Inhibitors of Human Protein Kinase CK2α

(2012) Romualda Wąsik et al.   PLoS One

Saturation Transfer Difference NMR Studies of the Interaction of the Proteinkinase CK2 with Peptides

(2012) Christoph Rauber et al.   PROTEIN AND PEPTIDE LETTERS

Tinkering outside the kinase ATP box: allosteric (type IV) and bivalent (type V) inhibitors of protein kinases

(2010) Kurt J Cox et al.   Future Medicinal Chemistry

Diversity of Bisubstrate Binding Modes of Adenosine Analogue–Oligoarginine Conjugates in Protein Kinase A and Implications for Protein Substrate Interactions

(2010) Alexander Pflug et al.   JOURNAL OF MOLECULAR BIOLOGY

Relative Role of Halogen Bonds and Hydrophobic Interactions in Inhibition of Human Protein Kinase CK2α by Tetrabromobenzotriazole and Some C(5)-Substituted Analogues

(2010) Romualda Wąsik et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Bisubstrate Inhibitors of Protein Kinases: from Principle to Practical Applications

(2009) Darja Lavogina et al.   ChemMedChem

Peptide Inhibitors Targeting Protein Kinases

(2009) Hagit Eldar-Finkelman et al.   CURRENT PHARMACEUTICAL DESIGN

Kinase conformations: A computational study of the effect of ligand binding

(2009) Volkhard Helms et al.   PROTEIN SCIENCE

High-field solution NMR spectroscopy as a tool for assessing protein interactions with small molecule ligands

(2008) Andria L. Skinner et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Structural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazole

(2002) Roberto Battistutta et al.   PROTEIN SCIENCE