CD271 is a molecular switch with divergent roles in melanoma and melanocyte development

Down-regulation of FZD3 receptor suppresses growth and metastasis of human melanoma independently of canonical WNT signaling

(2019) Chen Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systems biology analysis of mitogen activated protein kinase inhibitor resistance in malignant melanoma

(2018) Helma Zecena et al.   BMC Systems Biology

Immunotherapy Resistance by Inflammation-Induced Dedifferentiation

(2018) Arnav Mehta et al.   Cancer Discovery

Combined Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain

(2018) Hussein A. Tawbi et al.   NEW ENGLAND JOURNAL OF MEDICINE

RIP2 Gates TRAF6 Interaction with Death Receptor p75 NTR to Regulate Cerebellar Granule Neuron Survival

(2018) Lilian Kisiswa et al.   Cell Reports

DNA Damage in Stem Cells

(2017) Ilio Vitale et al.   MOLECULAR CELL

Beyond MITF: Multiple transcription factors directly regulate the cellular phenotype in melanocytes and melanoma

(2017) Hannah E. Seberg et al.   Pigment Cell & Melanoma Research

Paracrine regulation of melanocyte genomic stability: a focus on nucleotide excision repair

(2017) Stuart Gordon Jarrett et al.   Pigment Cell & Melanoma Research

CD271 determines migratory properties of melanoma cells

(2017) Josefine Radke et al.   Scientific Reports

Antibody Therapy Targeting CD47 and CD271 Effectively Suppresses Melanoma Metastasis in Patient-Derived Xenografts

(2016) Michael Ngo et al.   Cell Reports

CD271 is expressed in melanomas with more aggressive behaviour, with correlation of characteristic morphology byin vivoreflectance confocal microscopy

(2015) F. Beretti et al.   BRITISH JOURNAL OF DERMATOLOGY

Increased CD271 expression by the NF-kB pathway promotes melanoma cell survival and drives acquired resistance to BRAF inhibitor vemurafenib

(2015) Abdelali Lehraiki et al.   Cell Discovery

CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma

(2015) Oihana Murillo-Sauca et al.   Oncotarget

Transient TNF regulates the self-renewing capacity of stem-like label-retaining cells in sphere and skin equivalent models of melanoma

(2014) Pauline Ostyn et al.   Cell Communication and Signaling

Role of p75 neurotrophin receptor in stem cell biology: more than just a marker

(2014) Elisa Tomellini et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Epigenetic regulation of CD271, a potential cancer stem cell marker associated with chemoresistance and metastatic capacity

(2014) SULAN LI et al.   ONCOLOGY REPORTS

The Nerve Growth Factor Receptor CD271 Is Crucial to Maintain Tumorigenicity and Stem-Like Properties of Melanoma Cells

(2014) Torben Redmer et al.   PLoS One

CD271 on Melanoma Cell Is an IFN-γ-Inducible Immunosuppressive Factor that Mediates Downregulation of Melanoma Antigens

(2013) Junpei Furuta et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Stem cells and targeted approaches to melanoma cure

(2013) George F. Murphy et al.   MOLECULAR ASPECTS OF MEDICINE

Tumor Stem Cells (CD271, c-kit, SOX10) in Melanomas

(2013) Amr Mohamed et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

MYC on the Path to Cancer

(2012) Chi V. Dang   CELL

Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation

(2012) Jennifer Landsberg et al.   NATURE

VEGFR-1 Expressed by Malignant Melanoma-Initiating Cells Is Required for Tumor Growth

(2011) Natasha Y. Frank et al.   CANCER RESEARCH

Human CD271-Positive Melanoma Stem Cells Associated with Metastasis Establish Tumor Heterogeneity and Long-term Growth

(2011) G. Civenni et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Phenotypic Heterogeneity among Tumorigenic Melanoma Cells from Patients that Is Reversible and Not Hierarchically Organized

(2010) Elsa Quintana et al.   CANCER CELL

Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271

(2010) Alexander D. Boiko et al.   NATURE

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

(2009) Erika L. Pearce et al.   NATURE

Melanocytes in Development, Regeneration, and Cancer

(2008) Richard Mark White et al.   Cell Stem Cell

Efficient tumour formation by single human melanoma cells

(2008) Elsa Quintana et al.   NATURE