Ganglioside GQ1b ameliorates cognitive impairments in an Alzheimer’s disease mouse model, and causes reduction of amyloid precursor protein

A novel brain-derived neurotrophic factor-modulating peptide attenuates Aβ1-42-induced neurotoxicity in vitro

(2015) Min-Kyoo Shin et al.   NEUROSCIENCE LETTERS

Soluble Aβ Oligomers Are Rapidly Sequestered from Brain ISF In Vivo and Bind GM1 Ganglioside on Cellular Membranes

(2014) Soyon Hong et al.   NEURON

β-Amyloid (Aβ) Oligomers Impair Brain-derived Neurotrophic Factor Retrograde Trafficking by Down-regulating Ubiquitin C-terminal Hydrolase, UCH-L1

(2013) Wayne W. Poon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Object recognition test in mice

(2013) Marianne Leger et al.   Nature Protocols

Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques

(2013) Min-Kyoo Shin et al.   NEUROBIOLOGY OF AGING

The ganglioside GQ1b regulates BDNF expression via the NMDA receptor signaling pathway

(2013) Min Kyoo Shin et al.   NEUROPHARMACOLOGY

Tau protein phosphatases in Alzheimer's disease: The leading role of PP2A

(2012) Ludovic Martin et al.   AGEING RESEARCH REVIEWS

Amyloid-β induced toxicity involves ganglioside expression and is sensitive to GM1 neuroprotective action

(2011) Fernando Kreutz et al.   NEUROCHEMISTRY INTERNATIONAL

Characterization of the 3xTg-AD mouse model of Alzheimer's disease: Part 2. Behavioral and cognitive changes

(2010) Roxanne Sterniczuk et al.   BRAIN RESEARCH

Novel therapeutic approach for Alzheimer’s disease by removing amyloid β protein from the brain with an extracorporeal removal system

(2010) Kazunori Kawaguchi et al.   JOURNAL OF ARTIFICIAL ORGANS

Membrane Lipids, Selectively Diminished in Alzheimer Brains, Suggest Synapse Loss as a Primary Event in Early-Onset Form (Type I) and Demyelination in Late-Onset Form (Type II)

(2010) Lars Svennerholm et al.   JOURNAL OF NEUROCHEMISTRY

A novel trimeric peptide, Neuropep-1-stimulating brain-derived neurotrophic factor expression in rat brain improves spatial learning and memory as measured by the Y-maze and Morris water maze

(2010) Min Kyoo Shin et al.   JOURNAL OF NEUROCHEMISTRY

Activation of Extrasynaptic, But Not Synaptic, NMDA Receptors Modifies Amyloid Precursor Protein Expression Pattern and Increases Amyloid-  Production

(2010) K. Bordji et al.   JOURNAL OF NEUROSCIENCE

Exogenous gangliosides increase the release of brain-derived neurotrophic factor

(2010) Seung T. Lim et al.   NEUROPHARMACOLOGY

CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease

(2010) A. Caccamo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dietary zinc supplementation of 3xTg-AD mice increases BDNF levels and prevents cognitive deficits as well as mitochondrial dysfunction

(2010) C Corona et al.   Cell Death & Disease

Synaptic NMDA Receptor Activation Stimulates  -Secretase Amyloid Precursor Protein Processing and Inhibits Amyloid-  Production

(2009) S. E. Hoey et al.   JOURNAL OF NEUROSCIENCE

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

(2009) Alan H Nagahara et al.   NATURE MEDICINE

Thematic Review Series: Sphingolipids.Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease—a review,

(2008) Toshio Ariga et al.   JOURNAL OF LIPID RESEARCH

Protective effect of BDNF against beta-amyloid induced neurotoxicity in vitro and in vivo in rats

(2008) S. Arancibia et al.   NEUROBIOLOGY OF DISEASE

Ganglioside GQ1b improves spatial learning and memory of rats as measured by the Y-maze and the Morris water maze tests

(2008) Woo Ram Jung et al.   NEUROSCIENCE LETTERS