Differentiating SGBS adipocytes respond to PPARγ stimulation, irisin and BMP7 by functional browning and beige characteristics

Prediction of Adipose Browning Capacity by Systematic Integration of Transcriptional Profiles

(2018) Yiming Cheng et al.   Cell Reports

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

(2018) Hyeonwoo Kim et al.   CELL

BATLAS: Deconvoluting Brown Adipose Tissue

(2018) Aliki Perdikari et al.   Cell Reports

Teneurin-2 (TENM2) deficiency induces UCP1 expression in differentiating human fat cells

(2017) D. Tews et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

SGBS cells as a model of human adipocyte browning: A comprehensive comparative study with primary human white subcutaneous adipocytes

(2017) Chia Rou Yeo et al.   Scientific Reports

The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria

(2016) Jonathan Z. Long et al.   CELL

Clozapine modifies the differentiation program of human adipocytes inducing browning

(2016) E Kristóf et al.   Translational Psychiatry

AMP-Activated Kinase (AMPK) Activation by AICAR in Human White Adipocytes Derived from Pericardial White Adipose Tissue Stem Cells Induces a Partial Beige-Like Phenotype

(2016) Omar Abdul-Rahman et al.   PLoS One

A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat

(2015) Lawrence Kazak et al.   CELL

Brown and Beige Fat: Physiological Roles beyond Heat Generation

(2015) Shingo Kajimura et al.   Cell Metabolism

Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry

(2015) Mark P. Jedrychowski et al.   Cell Metabolism

Comprehensive molecular characterization of human adipocytes reveals a transient brown phenotype

(2015) Andrea Guennoun et al.   Journal of Translational Medicine

Angiotensin II directly impairs adipogenic differentiation of human preadipose cells

(2015) Marisol M. Palominos et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes

(2015) Ruidan Xue et al.   NATURE MEDICINE

Genetic and functional characterization of clonally derived adult human brown adipocytes

(2015) Kosaku Shinoda et al.   NATURE MEDICINE

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

(2015) Melina Claussnitzer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Laser-scanning cytometry can quantify human adipocyte browning and proves effectiveness of irisin

(2015) Endre Kristóf et al.   Scientific Reports

Atypical antipsychotics induce both proinflammatory and adipogenic gene expression in human adipocytes in vitro

(2014) Anitta K. Sárvári et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

What We Talk About When We Talk About Fat

(2014) Evan D. Rosen et al.   CELL

A Smooth Muscle-Like Origin for Beige Adipocytes

(2014) Jonathan Z. Long et al.   Cell Metabolism

Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans

(2014) Paul Lee et al.   Cell Metabolism

A Classical Brown Adipose Tissue mRNA Signature Partly Overlaps with Brite in the Supraclavicular Region of Adult Humans

(2013) Naja Zenius Jespersen et al.   Cell Metabolism

Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling

(2013) Y. Zhang et al.   DIABETES

FTO Deficiency Induces UCP-1 Expression and Mitochondrial Uncoupling in Adipocytes

(2013) D. Tews et al.   ENDOCRINOLOGY

Calcium-dependent release of adipocyte fatty acid binding protein from human adipocytes

(2013) I Schlottmann et al.   INTERNATIONAL JOURNAL OF OBESITY

Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat

(2013) Tim J. Schulz et al.   NATURE

Evidence for two types of brown adipose tissue in humans

(2013) Martin E Lidell et al.   NATURE MEDICINE

Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat

(2013) Aaron M Cypess et al.   NATURE MEDICINE

Evidence against a Beneficial Effect of Irisin in Humans

(2013) Silja Raschke et al.   PLoS One

Metabolically Active Human Brown Adipose Tissue Derived Stem Cells

(2013) Francisco J Silva et al.   STEM CELLS

Mechanism of Fatty-Acid-Dependent UCP1 Uncoupling in Brown Fat Mitochondria

(2012) Andriy Fedorenko et al.   CELL

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

PPARγ agonists Induce a White-to-Brown Fat Conversion through Stabilization of PRDM16 Protein

(2012) Haruya Ohno et al.   Cell Metabolism

The SGBS cell strain as a model for the in vitro study of obesity and cancer

(2012) Emma H. Allott et al.   Clinical & Translational Oncology

Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes

(2012) Marica Bordicchia et al.   JOURNAL OF CLINICAL INVESTIGATION

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Human BAT Possesses Molecular Signatures That Resemble Beige/Brite Cells

(2012) Louis Z. Sharp et al.   PLoS One

PAZ6 Cells Constitute a Representative Model for Human Brown Pre-Adipocytes

(2012) Melissa Kazantzis et al.   Frontiers in Endocrinology

Recruited vs. nonrecruited molecular signatures of brown, “brite,” and white adipose tissues

(2011) Tomas B. Waldén et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Poly(ADP-ribose) polymerase-2 depletion reduces doxorubicin-induced damage through SIRT1 induction

(2011) Magdolna Szántó et al.   CARDIOVASCULAR RESEARCH

Beige Can Be Slimming

(2010) J. Ishibashi et al.   SCIENCE

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

(2009) Natasa Petrovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Multipotent Adipose-Derived Stem Cells Differentiate into Functional Brown Adipocytes

(2009) Christian Elabd et al.   STEM CELLS

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

(2008) Yu-Hua Tseng et al.   NATURE

Human SGBS Cells – a Unique Tool for Studies of Human Fat Cell Biology

(2008) Pamela Fischer-Posovszky et al.   Obesity Facts