The histone methyltransferase Setd2 is indispensable for V(D)J recombination
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Title
The histone methyltransferase Setd2 is indispensable for V(D)J recombination
Authors
Keywords
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Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-07-26
DOI
10.1038/s41467-019-11282-x
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Note: Only part of the references are listed.- Setd2 deficiency impairs hematopoietic stem cell self-renewal and causes malignant transformation
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- Setd2 regulates quiescence and differentiation of adult hematopoietic stem cells by restricting RNA polymerase II elongation
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- Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2
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- H3K4me3 induces allosteric conformational changes in the DNA-binding and catalytic regions of the V(D)J recombinase
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- Histone methylation and V(D)J recombination
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- BS69/ZMYND11 Reads and Connects Histone H3.3 Lysine 36 Trimethylation-Decorated Chromatin to Regulated Pre-mRNA Processing
- (2014) Rui Guo et al. MOLECULAR CELL
- Mutations in epigenetic regulators including SETD2 are gained during relapse in paediatric acute lymphoblastic leukaemia
- (2014) Brenton G. Mar et al. Nature Communications
- SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint
- (2014) Sílvia Carvalho et al. eLife
- The Histone Mark H3K36me3 Regulates Human DNA Mismatch Repair through Its Interaction with MutSα
- (2013) Feng Li et al. CELL
- Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription
- (2013) Sílvia Carvalho et al. NUCLEIC ACIDS RESEARCH
- Localized DNA Demethylation at Recombination Intermediates during Immunoglobulin Heavy Chain Gene Assembly
- (2013) Roza Selimyan et al. PLOS BIOLOGY
- Set2 mediated H3 lysine 36 methylation: regulation of transcription elongation and implications in organismal development
- (2013) Swaminathan Venkatesh et al. Wiley Interdisciplinary Reviews-Developmental Biology
- The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3
- (2011) Jessica M. Jones et al. IMMUNOLOGY LETTERS
- Decision checkpoints in the thymus
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- Regulation of Alternative Splicing by Histone Modifications
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- Differential chromatin marking of introns and expressed exons by H3K36me3
- (2009) Paulina Kolasinska-Zwierz et al. NATURE GENETICS
- Reciprocal patterns of methylation of H3K36 and H3K27 on proximal vs. distal IgVH genes are modulated by IL-7 and Pax5
- (2008) C.-R. Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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