Mad1 destabilizes p53 by preventing PML from sequestering MDM2

The BUB3-BUB1 Complex Promotes Telomere DNA Replication

(2018) Feng Li et al.   MOLECULAR CELL

Sumoylation promotes optimal APC/C activation and timely anaphase

(2018) Christine C Lee et al.   eLife

Living in CIN: Mitotic Infidelity and Its Consequences for Tumor Promotion and Suppression

(2016) Laura C. Funk et al.   DEVELOPMENTAL CELL

Perforating the nuclear boundary – how nuclear pore complexes assemble

(2016) Marion Weberruss et al.   JOURNAL OF CELL SCIENCE

Negative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth

(2016) Konstantina Rowald et al.   Cell Reports

Mad1 at the Golgi apparatus: a story beyond kinetochores

(2015) Jun Wan et al.   CELL CYCLE

Identification of SUMO-2/3-modified proteins associated with mitotic chromosomes

(2015) Caelin Cubeñas-Potts et al.   PROTEOMICS

The function, regulation and therapeutic implications of the tumor suppressor protein, PML

(2015) Dongyin Guan et al.   Cell and Bioscience

Nuclear Pores Protect Genome Integrity by Assembling a Premitotic and Mad1-Dependent Anaphase Inhibitor

(2014) Veronica Rodriguez-Bravo et al.   CELL

A Golgi-Localized Pool of the Mitotic Checkpoint Component Mad1 Controls Integrin Secretion and Cell Migration

(2014) Jun Wan et al.   CURRENT BIOLOGY

Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint

(2014) N. London et al.   GENES & DEVELOPMENT

Analysis of TP53 Mutation Status in Human Cancer Cell Lines: A Reassessment

(2014) Bernard Leroy et al.   HUMAN MUTATION

A Bub1–Mad1 interaction targets the Mad1–Mad2 complex to unattached kinetochores to initiate the spindle checkpoint

(2014) Mark W. Moyle et al.   JOURNAL OF CELL BIOLOGY

Transient Activation of p53 in G2 Phase Is Sufficient to Induce Senescence

(2014) Lenno Krenning et al.   MOLECULAR CELL

GPS-SUMO: a tool for the prediction of sumoylation sites and SUMO-interaction motifs

(2014) Qi Zhao et al.   NUCLEIC ACIDS RESEARCH

Increased expression of Mitotic Arrest Deficient-Like 1 (MAD1L1) is associated with poor prognosis and insensitive to Taxol treatment in breast cancer

(2013) Qian Sun et al.   BREAST CANCER RESEARCH AND TREATMENT

2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells

(2013) Lauren M. Zasadil et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Differential Roles of PML Isoforms

(2013) Sébastien Nisole et al.   Frontiers in Oncology

SUMOylation in Control of Accurate Chromosome Segregation during Mitosis

(2012) Jun Wan et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Bub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression

(2012) Robin M. Ricke et al.   JOURNAL OF CELL BIOLOGY

Acute promyelocytic leukemia, arsenic, and PML bodies

(2012) Hugues de Thé et al.   JOURNAL OF CELL BIOLOGY

Mitosis-Specific Regulation of Nuclear Transport by the Spindle Assembly Checkpoint Protein Mad1p

(2012) Lucas V. Cairo et al.   MOLECULAR CELL

Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons

(2012) S. D. Ryan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of human Mad1 C-terminal domain reveals its involvement in kinetochore targeting

(2012) S. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BubR1 Is Modified by Sumoylation during Mitotic Progression

(2011) Feikun Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1–C-Mad2 core complex

(2010) Laura Hewitt et al.   JOURNAL OF CELL BIOLOGY

PML Nuclear Bodies

(2010) V. Lallemand-Breitenbach et al.   Cold Spring Harbor Perspectives in Biology

PML nuclear bodies as sites of epigenetic regulation

(2009) Dora Torok   Frontiers in Bioscience-Landmark

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

(2009) Andrew J. Holland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Systematic study of protein sumoylation: Development of a site-specific predictor of SUMOsp 2.0

(2009) Jian Ren et al.   PROTEOMICS

Tpr directly binds to Mad1 and Mad2 and is important for the Mad1-Mad2-mediated mitotic spindle checkpoint

(2008) S. H. Lee et al.   GENES & DEVELOPMENT

SUMO-2/3 Modification and Binding Regulate the Association of CENP-E with Kinetochores and Progression through Mitosis

(2008) Xiang-Dong Zhang et al.   MOLECULAR CELL

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Whole chromosome instability and cancer: a complex relationship

(2008) Robin M. Ricke et al.   TRENDS IN GENETICS