A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis
Published 2019 View Full Article
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Title
A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis
Authors
Keywords
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Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-05-20
DOI
10.1038/s41467-019-09773-y
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Note: Only part of the references are listed.- Multiple sclerosis risk variants alter expression of co-stimulatory genes in B cells
- (2018) Ide Smets et al. BRAIN
- Colocalization of GWAS and eQTL Signals Detects Target Genes
- (2016) Farhad Hormozdiari et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Personalized testing based on polygenic risk score is promising for more efficient population-based screening programs for common oncological diseases
- (2016) P. Radice et al. ANNALS OF ONCOLOGY
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- (2016) Yiwey Shieh et al. BREAST CANCER RESEARCH AND TREATMENT
- Foxo3 Transcription Factor Drives Pathogenic T Helper 1 Differentiation by Inducing the Expression of Eomes
- (2016) Caroline Stienne et al. IMMUNITY
- New polygenic risk score improves prediction of CHD
- (2016) Irene Fernández-Ruiz Nature Reviews Cardiology
- Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics
- (2016) David Lamparter et al. PLoS Computational Biology
- Tissue Specificity of Human Disease Module
- (2016) Maksim Kitsak et al. Scientific Reports
- P
- (2015) Anne-Sophie Jannot et al. JOURNAL OF CLINICAL EPIDEMIOLOGY
- Eomesodermin Expression in CD4+T Cells Restricts Peripheral Foxp3 Induction
- (2015) Ekaterina Lupar et al. JOURNAL OF IMMUNOLOGY
- Integrative analysis of 111 reference human epigenomes
- (2015) Anshul Kundaje et al. NATURE
- Innate immunological function of TH2 cells in vivo
- (2015) Liying Guo et al. NATURE IMMUNOLOGY
- ImmVar project: Insights and design considerations for future studies of “healthy” immune variation
- (2015) Philip L. De Jager et al. SEMINARS IN IMMUNOLOGY
- Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia
- (2015) Esben Agerbo et al. JAMA Psychiatry
- PINBPA: Cytoscape app for network analysis of GWAS data
- (2014) Lili Wang et al. BIOINFORMATICS
- The autoimmune disease-associated transcription factors EOMES and TBX21 are dysregulated in multiple sclerosis and define a molecular subtype of disease
- (2014) Grant P. Parnell et al. CLINICAL IMMUNOLOGY
- Essential Role of Elmo1 in Dock2-Dependent Lymphocyte Migration
- (2014) C. Stevenson et al. JOURNAL OF IMMUNOLOGY
- featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
- (2013) Y. Liao et al. BIOINFORMATICS
- Integrated Enrichment Analysis of Variants and Pathways in Genome-Wide Association Studies Indicates Central Role for IL-2 Signaling Genes in Type 1 Diabetes, and Cytokine Signaling Genes in Crohn's Disease
- (2013) Peter Carbonetto et al. PLoS Genetics
- HYST: A Hybrid Set-Based Test for Genome-wide Association Studies, with Application to Protein-Protein Interaction-Based Association Analysis
- (2012) Miao-Xin Li et al. AMERICAN JOURNAL OF HUMAN GENETICS
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Annotation of functional variation in personal genomes using RegulomeDB
- (2012) A. P. Boyle et al. GENOME RESEARCH
- Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
- (2012) M. T. Maurano et al. SCIENCE
- Prioritizing candidate disease genes by network-based boosting of genome-wide association data
- (2011) I. Lee et al. GENOME RESEARCH
- Eomesodermin Controls Interleukin-5 Production in Memory T Helper 2 Cells through Inhibition of Activity of the Transcription Factor GATA3
- (2011) Yusuke Endo et al. IMMUNITY
- The signaling networks of the herpesvirus entry mediator (TNFRSF14) in immune regulation
- (2011) Marcos W. Steinberg et al. IMMUNOLOGICAL REVIEWS
- What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations
- (2011) Orestis A Panagiotou et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Incorporating Biological Pathways via a Markov Random Field Model in Genome-Wide Association Studies
- (2011) Min Chen et al. PLoS Genetics
- Maps of Open Chromatin Guide the Functional Follow-Up of Genome-Wide Association Signals: Application to Hematological Traits
- (2011) Dirk S. Paul et al. PLoS Genetics
- Gene-Based Tests of Association
- (2011) Hailiang Huang et al. PLoS Genetics
- Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology
- (2011) Elizabeth J. Rossin et al. PLoS Genetics
- Prioritizing GWAS Results: A Review of Statistical Methods and Recommendations for Their Application
- (2010) Rita M. Cantor et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Aggregation of multiple sclerosis genetic risk variants in multiple and single case families
- (2010) Pierre-Antoine Gourraud et al. ANNALS OF NEUROLOGY
- Analysing biological pathways in genome-wide association studies
- (2010) Kai Wang et al. NATURE REVIEWS GENETICS
- Pathway and network-based analysis of genome-wide association studies in multiple sclerosis
- (2009) S. E. Baranzini et al. HUMAN MOLECULAR GENETICS
- Mer tyrosine kinase (MerTK) promotes macrophage survival following exposure to oxidative stress
- (2009) Adil Anwar et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score
- (2009) Philip L De Jager et al. LANCET NEUROLOGY
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