Cryo-Electron Microscopy Structure of an Acinetobacter baumannii Multidrug Efflux Pump

Using a SMALP platform to determine a sub-nm single particle cryo-EM membrane protein structure

(2018) Mayuriben Parmar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Substrate Specificities and Efflux Efficiencies of RND Efflux Pumps of Acinetobacter baumannii

(2018) Inga V. Leus et al.   JOURNAL OF BACTERIOLOGY

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

(2018) Evelina Tacconelli et al.   LANCET INFECTIOUS DISEASES

Real-space refinement in PHENIX for cryo-EM and crystallography

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

Structure and activity of lipid bilayer within a membrane-protein transporter

(2018) Weihua Qiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump

(2017) Chih-Chia Su et al.   Nature Communications

Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

(2017) Chang-Ro Lee et al.   Frontiers in Cellular and Infection Microbiology

Evidence of a Substrate-Discriminating Entrance Channel in the Lower Porter Domain of the Multidrug Resistance Efflux Pump AcrB

(2016) Sabine Schuster et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Rapid dissemination of colistin and carbapenem resistant Acinetobacter baumannii in Central Greece: mechanisms of resistance, molecular identification and epidemiological data

(2015) O. Oikonomou et al.   BMC INFECTIOUS DISEASES

Properties of AdeABC and AdeIJK Efflux Systems of Acinetobacter baumannii Compared with Those of the AcrAB-TolC System of Escherichia coli

(2014) Etsuko Sugawara et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Crystal Structure of the Neisseria gonorrhoeae MtrD Inner Membrane Multidrug Efflux Pump

(2014) Jani Reddy Bolla et al.   PLoS One

Antimicrobial resistance inAcinetobacter baumannii: From bench to bedside

(2014) Ming-Feng Lin   World Journal of Clinical Cases

Molecular Epidemiology and Mechanisms of Tigecycline Resistance in Clinical Isolates of Acinetobacter baumannii from a Chinese University Hospital

(2013) Mei Deng et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroResponses of Acinetobacter baumannii to Two- and Three-Drug Combinations following Exposure to Colistin and Doripenem

(2013) Louise M. Oleksiuk et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structural basis for the inhibition of bacterial multidrug exporters

(2013) Ryosuke Nakashima et al.   NATURE

Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System

(2012) Chih-Chia Su et al.   JOURNAL OF MOLECULAR BIOLOGY

Multidrug binding properties of the AcrB efflux pump characterized by molecular dynamics simulations

(2012) A. V. Vargiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Carbapenem-resistant Acinetobacter baumannii: diversity of resistant mechanisms and risk factors for infection

(2011) Y. J. KIM et al.   EPIDEMIOLOGY AND INFECTION

Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli

(2011) Chih-Chia Su et al.   NATURE

Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket

(2011) Ryosuke Nakashima et al.   NATURE

Overexpression of Resistance-Nodulation-Cell Division Pump AdeFGH Confers Multidrug Resistance in Acinetobacter baumannii

(2010) S. Coyne et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Multidrug-resistant Acinetobacter baumannii: mechanisms of virulence and resistance

(2010) Nicola C. Gordon et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport

(2010) Feng Long et al.   NATURE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Crystal Structure of the Multidrug Exporter MexB from Pseudomonas aeruginosa

(2009) Gaby Sennhauser et al.   JOURNAL OF MOLECULAR BIOLOGY

Acinetobacter baumannii: Emergence of a Successful Pathogen

(2008) A. Y. Peleg et al.   CLINICAL MICROBIOLOGY REVIEWS

The structure of the efflux pump AcrB in complex with bile acid

(2008) David Drew et al.   MOLECULAR MEMBRANE BIOLOGY