Efficient Expression of HIV in Immunocompetent Mouse Brain Reveals a Novel Nonneurotoxic Viral Function in Hippocampal Synaptodendritic Injury and Memory Impairment

Intranasal insulin therapy reverses hippocampal dendritic injury and cognitive impairment in a model of HAND in EcoHIV-infected mice

(2019) Boe-Hyun Kim et al.   AIDS

Persistent EcoHIV infection induces nigral degeneration in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-intoxicated mice

(2018) Katherine E. Olson et al.   JOURNAL OF NEUROVIROLOGY

EcoHIV infection of mice establishes latent viral reservoirs in T cells and active viral reservoirs in macrophages that are sufficient for induction of neurocognitive impairment

(2018) Chao-Jiang Gu et al.   PLoS Pathogens

N-(Pivaloyloxy)alkoxy-carbonyl Prodrugs of the Glutamine Antagonist 6-Diazo-5-oxo-l-norleucine (DON) as a Potential Treatment for HIV Associated Neurocognitive Disorders

(2017) Michael T. Nedelcovych et al.   JOURNAL OF MEDICINAL CHEMISTRY

When do models of NeuroAIDS faithfully imitate “the real thing”?

(2017) Benjamin B. Gelman et al.   JOURNAL OF NEUROVIROLOGY

The cognitive map in humans: spatial navigation and beyond

(2017) Russell A Epstein et al.   NATURE NEUROSCIENCE

Making Sense of Multifunctional Proteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to Transcription

(2017) Tyler B. Faust et al.   Annual Review of Virology

Effect of ageing on neurocognitive function by stage of HIV infection: evidence from the Multicenter AIDS Cohort Study

(2017) Karl Goodkin et al.   Lancet HIV

Chronic low-level expression of HIV-1 Tat promotes a neurodegenerative phenotype with aging

(2017) Alex M. Dickens et al.   Scientific Reports

The Chronicity of HIV Infection Should Drive the Research Strategy of NeuroHIV Treatment Studies: A Critical Review

(2016) Thomas M. Gates et al.   CNS DRUGS

HIV-associated neurocognitive disorder — pathogenesis and prospects for treatment

(2016) Deanna Saylor et al.   Nature Reviews Neurology

Increased Intrathecal Immune Activation in Virally Suppressed HIV-1 Infected Patients with Neurocognitive Impairment

(2016) Arvid Edén et al.   PLoS One

Identifying Neurocognitive Decline at 36 Months among HIV-Positive Participants in the CHARTER Cohort Using Group-Based Trajectory Analysis

(2016) Marie-Josée Brouillette et al.   PLoS One

Spatiotemporal profile of Map2 and microglial changes in the hippocampal CA1 region following pilocarpine-induced status epilepticus

(2016) Nicole D. Schartz et al.   Scientific Reports

Neuropsychological Impairment in Acute HIV and the Effect of Immediate Antiretroviral Therapy

(2015) Idil Kore et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Association of Hippocampal Magnetic Resonance Imaging With Learning and Memory Deficits in HIV-1–Seropositive Patients

(2015) Man Wang et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Multilevel analysis of neuropathogenesis of neurocognitive impairment in HIV

(2015) Andrew J. Levine et al.   JOURNAL OF NEUROVIROLOGY

Role of the macrophage in HIV-associated neurocognitive disorders and other comorbidities in patients on effective antiretroviral treatment

(2015) Jay Rappaport et al.   JOURNAL OF NEUROVIROLOGY

Prevalence of HIV-associated neurocognitive disorders in the Multicenter AIDS Cohort Study

(2015) Ned Sacktor et al.   NEUROLOGY

Neuropathology of HAND With Suppressive Antiretroviral Therapy: Encephalitis and Neurodegeneration Reconsidered

(2015) Benjamin B. Gelman   Current HIV/AIDS Reports

Behavioral assays with mouse models of Alzheimer's disease: Practical considerations and guidelines

(2014) Daniela Puzzo et al.   BIOCHEMICAL PHARMACOLOGY

Insulin-like growth factor 2 reverses memory and synaptic deficits in APP transgenic mice

(2014) M. Pascual-Lucas et al.   EMBO Molecular Medicine

An Infectious Murine Model for Studying the Systemic Effects of Opioids on Early HIV Pathogenesis in the Gut

(2014) Gregory M. Sindberg et al.   Journal of Neuroimmune Pharmacology

Asymptomatic HIV-associated neurocognitive impairment increases risk for symptomatic decline

(2014) I. Grant et al.   NEUROLOGY

Cerebrospinal Fluid (CSF) Neuronal Biomarkers across the Spectrum of HIV Infection: Hierarchy of Injury and Detection

(2014) Julia Peterson et al.   PLoS One

Prefrontal cortical regulation of fear learning

(2014) Marieke R. Gilmartin et al.   TRENDS IN NEUROSCIENCES

Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease

(2014) Linda Lee et al.   Scientific Reports

Cholesterol Regulates Syntaxin 6 Trafficking at trans-Golgi Network Endosomal Boundaries

(2014) Meritxell Reverter et al.   Cell Reports

Transmission of chimeric HIV by mating in conventional mice: prevention by pre-exposure antiretroviral therapy and reduced susceptibility during estrus

(2013) E. Hadas et al.   Disease Models & Mechanisms

Immune activation and HIV persistence: implications for curative approaches to HIV infection

(2013) Nichole R. Klatt et al.   IMMUNOLOGICAL REVIEWS

Enhanced Human Immunodeficiency Virus Type 1 Expression and Neuropathogenesis in Knockout Mice Lacking Type I Interferon Responses

(2013) Hongxia He et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Synaptic Dysfunction in the Hippocampus Accompanies Learning and Memory Deficits in Human Immunodeficiency Virus Type-1 Tat Transgenic Mice

(2012) Sylvia Fitting et al.   BIOLOGICAL PSYCHIATRY

Neuronal toxicity in HIV CNS disease

(2012) Jane Kovalevich et al.   Future Virology

Neurovirological Correlation With HIV-Associated Neurocognitive Disorders and Encephalitis in a HAART-Era Cohort

(2012) Benjamin B. Gelman et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

The National NeuroAIDS Tissue Consortium Brain Gene Array: Two Types of HIV-Associated Neurocognitive Impairment

(2012) Benjamin B. Gelman et al.   PLoS One

Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment

(2011) Jarek Harezlak et al.   AIDS

Working Memory: Theories, Models, and Controversies

(2011) Alan Baddeley   Annual Review of Psychology

Monocyte Mobilization, Activation Markers, and Unique Macrophage Populations in the Brain: Observations from SIV Infected Monkeys Are Informative with Regard to Pathogenic Mechanisms of HIV Infection in Humans

(2011) Kenneth Williams et al.   Journal of Neuroimmune Pharmacology

Mice Chronically Infected with Chimeric HIV Resist Peripheral and Brain Superinfection: A Model of Protective Immunity to HIV

(2011) Jennifer L. Kelschenbach et al.   Journal of Neuroimmune Pharmacology

TRAF6 and IRF7 Control HIV Replication in Macrophages

(2011) Mélissa Sirois et al.   PLoS One

Significant Effects of Antiretroviral Therapy on Global Gene Expression in Brain Tissues of Patients with HIV-1-Associated Neurocognitive Disorders

(2011) Alejandra Borjabad et al.   PLoS Pathogens

Cliniconeuropathologic correlates of human immunodeficiency virus in the era of antiretroviral therapy

(2010) I Everall et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors

(2010) Robert K. Heaton et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

(2010) R. K. Heaton et al.   NEUROLOGY

The synapsins: Key actors of synapse function and plasticity

(2010) F. Cesca et al.   PROGRESS IN NEUROBIOLOGY

Picomolar Amyloid-  Positively Modulates Synaptic Plasticity and Memory in Hippocampus

(2009) D. Puzzo et al.   JOURNAL OF NEUROSCIENCE

Impairments in memory and hippocampal function in HIV-positive vs HIV-negative women: A preliminary study

(2009) P. M. Maki et al.   NEUROLOGY

Cognitive Neuropsychology of HIV-Associated Neurocognitive Disorders

(2009) Steven Paul Woods et al.   NEUROPSYCHOLOGY REVIEW

The history of antiretrovirals: key discoveries over the past 25 years

(2009) Erik De Clercq   REVIEWS IN MEDICAL VIROLOGY

Executive function in older adults: A structural equation modeling approach.

(2008) Rachel Hull et al.   NEUROPSYCHOLOGY