Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APPswe/PS1ΔE9 Transgenic Mice

IGF-1, Inflammation and Retinal Degeneration: A Close Network

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Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

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Neuron and neuroblast numbers and cytogenesis in the dentate gyrus of aged APP swe /PS1 dE9 transgenic mice: Effect of long-term treatment with paroxetine

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Serotonin augmentation therapy by escitalopram has minimal effects on amyloid-β levels in early-stage Alzheimer’s-like disease in mice

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The role of Insulin-Like Growth Factor 1 (IGF-1) in brain development, maturation and neuroplasticity

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Amyloid-β deposition in mild cognitive impairment is associated with increased hippocampal activity, atrophy and clinical progression

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Cytokine-producing microglia have an altered beta-amyloid load in aged APP/PS1 Tg mice

(2015) Alicia A. Babcock et al.   BRAIN BEHAVIOR AND IMMUNITY

Myelin-specific T cells induce interleukin-1beta expression in lesion-reactive microglial-like cells in zones of axonal degeneration

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Immune attack: the role of inflammation in Alzheimer disease

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The Role of Neuronal Insulin/Insulin-Like Growth Factor-1 Signaling for the Pathogenesis of Alzheimer’s Disease: Possible Therapeutic Implications

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Fibrillar Amyloid-  Peptides Activate Microglia via TLR2: Implications for Alzheimer's Disease

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Longitudinal follow-up of autophagy and inflammation in brain of APPswePS1dE9 transgenic mice

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Age-associated dysregulation of microglial activation is coupled with enhanced blood-brain barrier permeability and pathology in APP/PS1 mice

(2014) Aedín M. Minogue et al.   NEUROBIOLOGY OF AGING

Dynamics of Hippocampal Neurogenesis in Adult Humans

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Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology

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Alternations of central insulin-like growth factor-1 sensitivity in APP/PS1 transgenic mice and neuronal models

(2013) Bing Zhang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Insulin-Like Growth Factor I, Insulin-like Growth factor Binding Protein 3, and Atrial Fibrillation in the Elderly

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(2013) Suzanne E Hickman et al.   NATURE NEUROSCIENCE

Brain  -amyloid load approaches a plateau

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Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology

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The effect of ageing on neurogenesis and oxidative stress in the APPswe/PS1deltaE9 mouse model of Alzheimer's disease

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Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

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Beta-Amyloid Monomer and Insulin/IGF-1 Signaling in Alzheimer's Disease

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The many faces of insulin-like peptide signalling in the brain

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Reactive Glia not only Associates with Plaques but also Parallels Tangles in Alzheimer's Disease

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The ageing systemic milieu negatively regulates neurogenesis and cognitive function

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Cholinergic axon length reduced by 300 meters in the brain of an Alzheimer mouse model

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Short-Term Environmental Enrichment Rescues Adult Neurogenesis and Memory Deficits in APPSw,Ind Transgenic Mice

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Exercise-Induced Cognitive Plasticity, Implications for Mild Cognitive Impairment and Alzheimer’s Disease

(2011) Philip P. Foster et al.   Frontiers in Neurology

Neurogenesis in mouse models of Alzheimer's disease

(2010) Tsu Tshen Chuang   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A Meta-Analysis of Cytokines in Alzheimer's Disease

(2010) Walter Swardfager et al.   BIOLOGICAL PSYCHIATRY

Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis

(2010) Amanda Sierra et al.   Cell Stem Cell

Increased BMP6 Levels in the Brains of Alzheimer's Disease Patients and APP Transgenic Mice Are Accompanied by Impaired Neurogenesis

(2010) L. Crews et al.   JOURNAL OF NEUROSCIENCE

Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice

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Mass spectrometry in high-throughput proteomics: ready for the big time

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Early onset amyloid lesions lead to severe neuritic abnormalities and local, but not global neuron loss in APPPS1 transgenic mice

(2010) Niels J. Rupp et al.   NEUROBIOLOGY OF AGING

Murine Features of Neurogenesis in the Human Hippocampus across the Lifespan from 0 to 100 Years

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Pharmacomimetics of Exercise: Novel Approaches for Hippocampally- Targeted Neuroprotective Agents

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Microglia Protect Neurons against Ischemia by Synthesis of Tumor Necrosis Factor

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Systemic inflammation and disease progression in Alzheimer disease

(2009) C. Holmes et al.   NEUROLOGY

Mechanisms and Functional Implications of Adult Neurogenesis

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Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice

(2008) Bettina H Clausen et al.   Journal of Neuroinflammation

Amyloid Pathology Is Associated with Progressive Monoaminergic Neurodegeneration in a Transgenic Mouse Model of Alzheimer's Disease

(2008) Y. Liu et al.   JOURNAL OF NEUROSCIENCE

Dynamics of the Microglial/Amyloid Interaction Indicate a Role in Plaque Maintenance

(2008) T. Bolmont et al.   JOURNAL OF NEUROSCIENCE

Microglial Dysfunction and Defective  -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice

(2008) S. E. Hickman et al.   JOURNAL OF NEUROSCIENCE

Synaptic contact number and size in stratum radiatum CA1 of APP/PS1ΔE9 transgenic mice

(2008) Mark J. West et al.   NEUROBIOLOGY OF AGING