E3 ligase ASB8 promotes porcine reproductive and respiratory syndrome virus proliferation by stabilizing the viral Nsp1α protein and degrading host IKKβ kinase
E3 ligase ASB8 promotes porcine reproductive and respiratory syndrome virus proliferation by stabilizing the viral Nsp1α protein and degrading host IKKβ kinase
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Keywords
Ubiquitination, Ankyrin repeat and SOCS box–containing 8 (ASB8), IκB kinase β (IKKβ), Porcine reproductive and respiratory syndrome virus (PRRSV), Nonstructural protein 1α (Nsp1α), NF-κB signaling
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