Article
Biochemistry & Molecular Biology
Yuheng Tao, Junmei Ma, Caoxing Huang, Chenhuan Lai, Zhe Ling, Qiang Yong
Summary: Different types of salts added to galactomannan solutions can affect their viscosity and intermolecular interactions, thereby manipulating their rheological properties.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Multidisciplinary
Philipp Dullinger, Dominik Horinek
Summary: In recent years, it has been increasingly recognized that nanometer-sized ions exhibit superchaotropic effects in solution, resembling typical surfactants. However, the extension of the Hofmeister series to nanoions has not been achieved. By studying a generic model and conducting molecular dynamics simulations, a qualitative classification scheme based on ion size as a second dimension is proposed and supported.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Physical
Marius R. Bittermann, Marion Grzelka, Sander Woutersen, Albert M. Brouwer, Daniel Bonn
Summary: The relationship between fluorescence intensity and macroscopic viscosity can be described by the classical Forster-Hoffmann equation, with the value of the FH exponent depending on the polymer chain length. By plotting fluorescence against polymer concentration, all data can be collapsed onto a master curve, explaining the phenomenon in terms of the characteristic mesh size of the polymer solution. Known scaling laws for polymers can quantitatively explain the relation between the FH exponent and polymer chain length, linking nano- to macroviscosity.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Biochemistry & Molecular Biology
Daniel Sebena, Kevin Rudolph, Bibhisan Roy, Christoph Woelper, Till Nitschke, Sarah Lampe, Michael Giese, Jens Voskuhl
Summary: This article presents fluorescent guanidiniocarbonyl-indoles as versatile oxo-anion binders, comparing their photophysical properties and binding behavior with the well-known guanidiniocarbonyl-pyrrole. The study found that the guanidiniocarbonyl-indoles efficiently bind carboxylates, phosphonates, and sulfonates, making them promising emissive oxo-anion binders. Additionally, the introduction of a methoxy-group successfully shifted the excitation and emission wavelength closer to the visible region, making them interesting for biological applications.
Article
Chemistry, Physical
Makoto Yamazaki, Makoto Yabe, Kazutoshi Iijima
Summary: Polysaccharide-based polyelectrolyte complex (PEC) particles are widely used in drug delivery systems and material development. The aggregation mechanism of PEC particles in the presence of salts, especially the specific ion effects, has been investigated using chitosan and chondroitin sulfate C as model systems. It was found that weakly hydrated chaotropic ions promote the aggregation of PEC particles and increase their hydrophobicity. Molecular dynamics simulations suggested that ions can strengthen the hydrophobicity of PECs through changes in ion pairs and hydrophobic interactions. Controlling the surface hydrophilicity or hydrophobicity is an effective approach for controlling the stability of PEC particles in the presence of ions.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Pan Wang, Shixian Cao, Ting Yin, Xin-Long Ni
Summary: This study demonstrates a novel tunable hydrophobic effect in self-assembly of a small cationic organic fluorophore (NI-TPy+) with aggregation-induced emission (ALE) property in aqueous solution. The amplification of hydrophobicity was found to be significantly dependent upon the increasing aggregates of NI-TPy+, enabling the study of hydrophobic binding with chaotropic anions in the Hofmeister series.
CHINESE CHEMICAL LETTERS
(2021)
Article
Chemistry, Analytical
Alexander S. Oshchepkov, Elisabete Cruz Da Silva, Boris S. Morozov, Ilya O. Aparin, Evgeny A. Kataev, Andrey S. Klymchenko
Summary: Negatively charged phospholipids can be used as biomarkers for detecting apoptosis, drug-induced phospholipidosis, and bacteria. Developing fluorescent probes that can selectively recognize specific phospholipids is a promising solution to this challenge.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Applied
Congde Qiao, Xujie Wang, Jianlong Zhang, Jinshui Yao
Summary: The study found that strongly hydrated anions facilitate gelation of gelatin solutions, while weakly hydrated anions hinder the formation of gel structures. The gelation temperature of proteins is directly correlated to the hydration entropy of anions, indicating different salts have distinct effects on gel structures.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Organic
Lindsey O. Calabretta, Yana D. Petri, Ronald T. Raines
Summary: We report the synthesis and properties of a rationally designed guanidinium-containing oxoanion binder, GADAC. GADAC binds to carboxylates, phosphates, and sulfates with high affinities. GADAC is fluorescent in water and its quantum yield is pH-sensitive.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Francesco Bartoli, Luca Conti, Giammarco Maria Romano, Lara Massai, Paola Paoli, Patrizia Rossi, Giangaetano Pietraperzia, Cristina Gellini, Andrea Bencini
Summary: The synthesis of three new polyamine receptors based on a common cyclen platform with different appended fluorophores was reported. The study showed that the structural features of these receptors are controlled by a balance between hydrogen bonding and electrostatic repulsions in their protonated species, while their emission properties are tuned by photoinduced electron and/or proton transfer processes.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Analytical
Kentaro Watanabe, Tatsukichi Watanabe, Shunsuke Kimura, Hidekazu Ikezaki, Kiyoshi Toko
Summary: This study investigates the characteristics of lipid polymer membranes and sensors in solutions with different anions. The results show that the size and hydration energy of the ions affect the positive charge and membrane potential. Different lipid compositions of the sensors result in different ion selectivity. Furthermore, the lipid concentration also influences the ion selectivity.
Article
Chemistry, Multidisciplinary
Christopher J. Serpell, Ah Young Park, Carol V. Robinson, Paul D. Beer
Summary: A novel catenated system dense in cationic hydrogen bonding imidazolium units was described, showing a preference for binding of bromide over other halides under aqueous conditions, overcoming basicity and Hofmeister trends. This is the first example of an imidazolium-based catenane acting as an anion host through C-H hydrogen bonding.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Andrew Docker, Yuen Cheong Tse, Hui Min Tay, Andrew J. Taylor, Zongyao Zhang, Paul D. Beer
Summary: Exceptionally strong halogen bonding is utilized to synthesize chloride anion template XB [2]rotaxane host systems with heightened affinities. These host systems exhibit significantly enhanced affinities for hydrophilic ions in aqueous-organic media, while their affinities for hydrophobic ions are diminished, resulting in anti-Hofmeister bias.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Physical
Alexander Spreinat, Maria M. Dohmen, Jan Luettgens, Niklas Herrmann, Lars F. Klepzig, Robert Nissler, Sabrina Weber, Florian A. Mann, Jannika Lauth, Sebastian Kruss
Summary: Single-wall carbon nanotubes can assemble with biopolymers to form highly sensitive biosensors, with their fluorescence changing when interacting with analytes. By exploiting quantum defects in the carbon lattice of SWCNTs, processes and rate constants involved in photophysical signal transduction have been identified. Additionally, the fluorescence response of SWCNTs is influenced by both their length and non-radiative rate constants.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Chemistry, Multidisciplinary
Bradley A. Rogers, Halil Okur, Chuanyu Yan, Tinglu Yang, Jan Heyda, Paul S. Cremer
Summary: Research has shown that weakly hydrated anions can solubilize macromolecules but cause small molecules made from identical chemical constituents to precipitate out. This phenomenon can be explained by the regulation of anion binding to polymers by molecular curvature and interfacial water structure. The interactions of NaSCN with polyethylene oxide oligomers and polymers of varying molecular weight reveal a link between ion-specific effects and theories addressing how hydrophobic hydration is modulated by the size and shape of a hydrophobic entity.
Article
Chemistry, Physical
Bruna L. Kuhn, Barbara F. Osmari, Thaise M. Heinen, Helio G. Bonacorso, Nilo Zanatta, Steven O. Nielsen, Dineli T. S. Ranathunga, Marcos A. Villetti, Clarissa P. Frizzo
JOURNAL OF MOLECULAR LIQUIDS
(2020)
Article
Chemistry, Multidisciplinary
Dineli T. S. Ranathunga, Alexandra Shamir, Xianming Dai, Steven O. Nielsen
Article
Multidisciplinary Sciences
Hetao Chu, Xinghao Hu, Zhong Wang, Jiuke Mu, Na Li, Xiaoshuang Zhou, Shaoli Fang, Carter S. Haines, Jong Woo Park, Si Qin, Ningyi Yuan, Jiang Xu, Sameh Tawfick, Hyungjun Kim, Patrick Conlin, Maenghyo Cho, Kyeongjae Cho, Jiyoung Oh, Steven Nielsen, Kevin A. Alberto, Joselito M. Razal, Javad Foroughi, Geoffrey M. Spinks, Seon Jeong Kim, Jianning Ding, Jinsong Leng, Ray H. Baughman
Summary: The study found unipolar stroke carbon nanotube yarn muscles with enhanced stroke, contractile work-per-cycle, contractile power densities, and energy conversion efficiencies, offering potential for expanding their applications.
Article
Chemistry, Multidisciplinary
Dineli T. S. Ranathunga, Alexandra Arteaga, Claudia C. Biguetti, Danieli C. Rodrigues, Steven O. Nielsen
Summary: Titanium is favored as the material for orthopedic and dental implants due to its excellent chemical and mechanical properties, promoting rehabilitation through bone anchorage and osseointegration. The release of HMGB1 protein upon implantation leads to surgical trauma and affects inflammation and tissue healing. Understanding HMGB1-TiO2 interactions is crucial for developing surface strategies to improve the clinical outcome of titanium-based implants.
Article
Chemistry, Multidisciplinary
Ke Ji, Kiheon Baek, Weicheng Peng, Kevin A. Alberto, Hedieh Torabifard, Steven O. Nielsen, Sheel C. Dodani
Summary: Through a hybrid approach of biophysics and in silico analysis, we characterized the thermodynamic properties and protein dynamics of NrtA protein in recognizing nitrate and nitrite.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Physical
Blake A. Wilson, Steven O. Nielsen, Jaona H. Randrianalisoa, Zhenpeng Qin
Summary: This study investigates the heat transfer through nanoscale gold-water interfaces using atomistic molecular dynamics simulations. The researchers find that the thermal interface conductance increases linearly with interface curvature, regardless of gold wettability, and it increases nonlinearly with the applied heat flux under normal wetting. It remains constant under reduced wetting. The dependence on curvature may be linked to changes in interfacial water adsorption, while the temperature dependence may arise from shifts in the distribution of water vibrational states. This study advances our understanding of interface thermal conductance.
JOURNAL OF CHEMICAL PHYSICS
(2022)
Article
Physics, Applied
Enlai Gao, Xiaoang Yuan, Steven O. Nielsen, Ray H. Baughman
Summary: In this study, theoretical expressions for predicting the upper bounds of Young's modulus and gravimetric Young's modulus were developed and verified through experiments. Additionally, the application of lateral pressure on carbyne crystals showed that the calculated values were close to the predicted bounds.
PHYSICAL REVIEW APPLIED
(2022)
Article
Chemistry, Multidisciplinary
Alexandra Arteaga, Dineli T. S. Ranathunga, Jiayi Qu, Claudia C. Biguetti, Steven O. Nielsen, Danieli C. Rodrigues
Summary: This study investigates the use of dicationic imidazolium-based ionic liquids (IonLs) containing phenylalanine and methionine anions as a surface treatment for titanium implants. The results show that IonL-Phe has stronger interactions with the protein and higher stability, making it a potential strategy to promote osseointegration.
Article
Chemistry, Physical
Dineli T. S. Ranathunga, Hedieh Torabifard
Summary: Through molecular dynamics simulations, this study reveals the crucial role of BRCA1/BARD1-UbcH5c in the ubiquitination of H2A C-tail, providing insights into the mechanism of ubiquitination and offering potential therapeutic approaches for cancer and chronic pain.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Chemistry, Multidisciplinary
Weicheng Peng, Caden C. Maydew, Hiu Kam, Jacob K. Lynd, Jasmine N. Tutol, Shelby M. Phelps, Sameera Abeyrathna, Gabriele Meloni, Sheel C. Dodani
Summary: Chloride is crucial for all forms of life and recent research has demonstrated the potential of chloride-sensitive fluorescent proteins for cellular applications. This study presents a bioinformatics strategy to efficiently identify and design new chloride-sensitive fluorescent proteins, using GFPxm163 as an example.
Article
Materials Science, Multidisciplinary
Enlai Gao, Yongzhe Guo, Zhengzhi Wang, Steven O. Nielsen, Ray H. Baughman
Summary: In this study, the stability, strength, and toughness of B, C, BC, and BN chains were investigated using first-principles calculations. It was found that BC chains exhibited the highest recorded gravimetric strength and high toughness, surpassing the predicted performance of carbyne.
Article
Biochemistry & Molecular Biology
Regina A. Baglia, Kira R. Mills, Koushambi Mitra, Jasmine N. Tutol, Darby Ball, Kierstin M. Page, Jyothi Kallu, Sriharika Gottipolu, Sheena D'Arcy, Steven O. Nielsen, Sheel C. Dodani
Summary: Human phenol sulfotransferases play a role in transferring sulfuryl moieties from sulfate donors to substrates, affecting metabolism and cell signaling. The development and biological application of STS-3, a fluorescent sensor for the SULT1A1 isoform, are discussed in the paragraph.
RSC CHEMICAL BIOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Hamilton Lee, Arezoo Shahrivarkevishahi, Jenica L. Lumata, Michael A. Luzuriaga, Laurel M. Hagge, Candace E. Benjamin, Olivia R. Brohlin, Christopher R. Parish, Hamid R. Firouzi, Steven O. Nielsen, Lloyd L. Lumata, Jeremiah J. Gassensmith