Kynurenine signaling through the aryl hydrocarbon receptor maintains the undifferentiated state of human embryonic stem cells

An endogenous tryptophan photo-product, FICZ, is potentially involved in photo-aging by reducing TGF-β-regulated collagen homeostasis

(2018) Mika Murai et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Differentiation potential of Pluripotent Stem Cells correlates to the level of CHD7

(2018) Takako Yamamoto et al.   Scientific Reports

Integrative transcriptome and microRNome analysis identifies dysregulated pathways in human Sertoli cells exposed to TCDD

(2018) Mariana A. Ribeiro et al.   TOXICOLOGY

Astrocytic and neuronal localization of kynurenine aminotransferase-2 in the adult mouse brain

(2016) Judit Herédi et al.   Brain Structure & Function

Glycolysis-Mediated Changes in Acetyl-CoA and Histone Acetylation Control the Early Differentiation of Embryonic Stem Cells

(2015) Arieh Moussaieff et al.   Cell Metabolism

Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy

(2015) L. Zhai et al.   CLINICAL CANCER RESEARCH

Tryptophan derivatives regulate the transcription of Oct4 in stem-like cancer cells

(2015) Jie Cheng et al.   Nature Communications

A tryptophan metabolite, kynurenine, promotes mast cell activation through aryl hydrocarbon receptor

(2014) H. Kawasaki et al.   ALLERGY

Methionine Metabolism Regulates Maintenance and Differentiation of Human Pluripotent Stem Cells

(2014) Nobuaki Shiraki et al.   Cell Metabolism

Pluripotent stem cell energy metabolism: an update

(2014) T. Teslaa et al.   EMBO JOURNAL

Lysine metabolism in mammalian brain: an update on the importance of recent discoveries

(2013) André Hallen et al.   AMINO ACIDS

The kynurenine pathway in neurodegenerative diseases: Mechanistic and therapeutic considerations

(2012) Lin Tan et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Generation of Virus-Free Induced Pluripotent Stem Cell Clones on a Synthetic Matrix via a Single Cell Subcloning in the Naïve State

(2012) Naoki Nishishita et al.   PLoS One

Reference Maps of Human ES and iPS Cell Variation Enable High-Throughput Characterization of Pluripotent Cell Lines

(2011) Christoph Bock et al.   CELL

Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming

(2011) Clifford D.L. Folmes et al.   Cell Metabolism

FGF2 Sustains NANOG and Switches the Outcome of BMP4-Induced Human Embryonic Stem Cell Differentiation

(2011) Pengzhi Yu et al.   Cell Stem Cell

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

(2011) Christiane A. Opitz et al.   NATURE

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

NANOG Is a Direct Target of TGFβ/Activin-Mediated SMAD Signaling in Human ESCs

(2008) Ren-He Xu et al.   Cell Stem Cell