Article
Medicine, General & Internal
Yotam Deri, Baruch Berzon, Debra West, Matan Machloof, Refael Strugo, Tomer Kaplan, Shelly Soffer
Summary: In recent years, efforts have been made to improve the survival rate of out-of-hospital cardiac arrest (OHCA) patients, including placing defibrillators in public places and training first responders. This study retrospectively analyzed data from OHCA patients in Ashdod city, Israel, and found that the initial rhythm, use of defibrillators, and hospital interventions were important factors influencing patient outcomes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Critical Care Medicine
Takafumi Obara, Tetsuya Yumoto, Tsuyoshi Nojima, Takashi Hongo, Kohei Tsukahara, Naomi Matsumoto, Takashi Yorifuji, Atsunori Nakao, Jonathan Elmer, Hiromichi Naito
Summary: This study aimed to investigate the association between prehospital physician presence and neurologic outcomes in pediatric patients with out-of-hospital cardiac arrest (OHCA). The data from the Japanese Association for Acute Medicine-OHCA Registry were analyzed in a retrospective cohort study. The results showed that among pediatric patients with OHCA, prehospital physician presence was associated with a nearly two-fold increase in the odds of 1-month favorable neurologic outcomes.
PEDIATRIC CRITICAL CARE MEDICINE
(2023)
Article
Critical Care Medicine
Ziad Nehme, Jocasta Ball, Michael Stephenson, Tony Walker, Dion Stub, Karen Smith
Summary: The study revealed that implementing a high-performance CPR resuscitation quality improvement program significantly increased survival rates following OHCA, with a 33% increase in risk-adjusted odds of survival over the 12-month intervention period. The average marginal effect of the intervention resulted in 8.7 additional survivors per million population.
Article
Emergency Medicine
Sanae Hosomi, Ling Zha, Kosuke Kiyohara, Tetsuhisa Kitamura, Taro Irisawa, Hiroshi Ogura, Jun Oda
Summary: This study aimed to investigate the association between sex and prehospital advanced cardiac life support (ACLS) interventions provided by emergency medical services in Japan. The study found that females received fewer prehospital ACLS interventions than males, and this disparity was consistent across different subgroups. The study suggests that emergency medical service staff should be aware of this disparity and provide training to improve access to prehospital ACLS interventions for females.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2023)
Review
Medicine, General & Internal
Cheng-Ying Chiang, Ket-Cheong Lim, Pei Chun Lai, Tou-Yuan Tsai, Yen Ta Huang, Ming-Jen Tsai
Summary: This study conducted a meta-analysis comparing the effects of mechanical and manual CPR applied in the pre-hospital stage on clinical outcomes after OHCA in adults. The results showed that compared to manual CPR, pre-hospital use of mechanical CPR had a positive effect in achieving ROSC and survival to admission. However, the difference in survival to discharge and discharge with favorable neurological status remains inconclusive.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Tsuyoshi Nojima, Hiromichi Naito, Takafumi Obara, Kohei Ageta, Hiromasa Yakushiji, Tetsuya Yumoto, Noritomo Fujisaki, Atsunori Nakao
Summary: This study demonstrated that blood ammonia levels can predict neurological outcomes in patients with out-of-hospital cardiac arrest, with different cut-off values for patients with or without return of spontaneous circulation (ROSC) at hospital arrival.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Emergency Medicine
SungJoon Park, Sung Woo Lee, Kap Su Han, Eui Jung Lee, Dong-Hyun Jang, Si Jin Lee, Ji Sung Lee, Su Jin Kim
Summary: This study aimed to determine the optimal cut-off time and transition method for cardio-pulmonary resuscitation (CPR) duration. The study showed that in patients with non-traumatic out-of-hospital cardiac arrest, the optimal cut-off for pre-hospital CPR duration was 12 minutes, while the optimal cut-offs for transitioning from conventional CPR to alternative CPR methods were 25 minutes and 21 minutes. Despite the existence of an upper limit for CPR duration, favorable neurological outcomes can still be expected based on resuscitation-related factors for each patient.
SCANDINAVIAN JOURNAL OF TRAUMA RESUSCITATION & EMERGENCY MEDICINE
(2022)
Article
Medicine, General & Internal
Eujene Jung, Young Sun Ro, Jeong Ho Park, Hyun Ho Ryu, Sang Do Shin
Summary: Direct transport of out-of-hospital cardiac arrest (OHCA) patients to cardiac arrest centers (CACs) is associated with better clinical outcomes, particularly in non-metropolitan areas.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Eujene Jung, Young Sun Ro, Hyun Ho Ryu, Sang Do Shin
Summary: This study investigated the association between prehospital advanced airway management techniques and survival outcomes in out-of-hospital cardiac arrest patients in Korea. The results showed that patients who received endotracheal intubation and supraglottic airway management had a higher odds of survival to hospital discharge compared to those who received bag-valve mask management. Furthermore, the effect of prehospital airway management on clinical outcomes was influenced by the transport time interval.
Article
Multidisciplinary Sciences
Jun Nakajima, Yusuke Sawada, Yuta Isshiki, Yumi Ichikawa, Kazunori Fukushima, Yuto Aramaki, Kiyohiro Oshima
Summary: The prehospital administered dosage of epinephrine influences the plasma levels of Ep, but does not contribute to the plasma levels of norepinephrine (Nep), dopamine (DOA) and vasopressin (ADH) in patients with out-of-hospital cardiac arrest (OHCA).
Article
Critical Care Medicine
Lorenzo Gamberini, Carlo Alberto Mazzoli, Davide Allegri, Tommaso Scquizzato, Simone Baroncini, Martina Guarnera, Marco Tartaglione, Valentina Chiarini, Cosimo Picoco, Federico Semeraro, Giovanni Gordini, Carlo Coniglio
Summary: This study investigates factors associated with clinicians' decision to initiate or continue advanced life support (ALS) and finds significant inter-physician variability. Factors such as age, location of event, bystander cardiopulmonary resuscitation, and physician experience are found to be related. The observed variability calls for addressing ethical concerns within the EMS team.
Article
Emergency Medicine
Jiri Karasek, Jiri Seiner, Metodej Renza, Frantisek Salanda, Martin Moudry, Matej Strycek, Jan Lejsek, Rostislav Polasek, Petr Ostadal
Summary: This study analyzed data from a regional CAC's prospective OHCA registry and found that patients transported to a CAC had significantly longer transport times, but hemodynamic parameters and outcomes were not affected.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Medicine, General & Internal
Ji Han Heo, Taegyun Kim, Jonghwan Shin, Gil Joon Suh, Joonghee Kim, Yoon Sun Jung, Seung Min Park, Sungwan Kim
Summary: This study established a prediction model for predicting 1-year neurological outcomes in OHCA survivors using machine learning methods. The ensemble model showed higher performance compared to the multivariable logistic regression model, but performance slightly decreased in the external validation dataset.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2021)
Article
Multidisciplinary Sciences
Kota Shinada, Ayaka Matsuoka, Hiroyuki Koami, Yuichiro Sakamoto
Summary: This study utilized a Bayesian network to identify variables closely associated with good neurological survival outcomes in patients with OHCA. The variables identified were GCS M score of 2-6, initial rhythm (spontaneous rhythm and shockable), younger age, and absence of epinephrine, which could assist clinicians in decision-making for treating OHCA patients.
Article
Cardiac & Cardiovascular Systems
Martin Jonsson, Ellinor Berglund, Enrico Baldi, Maria Luce Caputo, Angelo Auricchio, Marieke T. Blom, Hanno L. Tan, Remy Stieglis, Linn Andelius, Fredrik Folke, Jacob Hollenberg, Leif Svensson, Mattias Ringh, ESCAPE NET Investigators
Summary: Activation of a volunteer responder system in cases of out-of-hospital cardiac arrest (OHCA) was associated with higher rates of bystander CPR, bystander defibrillation, and 30-day survival compared to no system activation. A randomized controlled trial is necessary to determine the causal effect of volunteer responder systems.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Letter
Emergency Medicine
Almaz S. Dessie, Resa E. Lewiss, Lori A. Stolz, Josie Acuna, Srikar Adhikari, David Amponsah, Marina Del Rios, Rob D. Huang, R. Starr Knight, Adaira Landry, Rachel B. Liu, Michael Gottlieb, Lorraine Ng, Nova L. Panebianco, Javier Rosario, AnthonyJ. Weekes, Jodi D. Jones
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Medical Informatics
Samuel Harford, Marina Del Rios, Sara Heinert, Joseph Weber, Eddie Markul, Katie Tataris, Teri Campbell, Terry Vanden Hoek, Houshang Darabi
Summary: This study developed machine learning models that effectively predicted whether hospitals would perform coronary angiography on OHCA patients and their subsequent neurologic outcomes. The models showed good predictive performance, and can help improve treatment strategies and policies for OHCA.
BMC MEDICAL INFORMATICS AND DECISION MAKING
(2022)
Article
Emergency Medicine
Javier Rosario, Resa E. Lewiss, Lori A. Stolz, Marina Del Rios, Josie Acuna, Srikar Adhikari, David Amponsah, Almaz S. Dessie, Michael Gottlieb, Robert D. Huang, Jodi Jones, Adaira Landry, Rachel B. Liu, Lorraine Ng, Nova L. Panebianco, Anthony J. Weekes, Starr Knight
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Medical Informatics
M. Pishgar, J. Theis, M. Del Rios, A. Ardati, H. Anahideh, H. Darabi
Summary: This study presented a process mining/deep learning approach to predict unplanned 30-day readmissions of ICU patients with HF, which significantly outperformed existing literature and baseline models by modeling time-related variables and incorporating patients' medical history.
BMC MEDICAL INFORMATICS AND DECISION MAKING
(2022)
Review
Critical Care Medicine
Adam J. Boulton, Marina Del Rios, Gavin D. Perkins
Summary: This review discusses the health inequities faced by out-of-hospital cardiac arrest patients and proposes solutions. Research shows significant disparities in different regions and ethnic groups, including low rates of CPR and AED usage, as well as unequal distribution of medical resources. These inequities result in lower survival rates among disadvantaged communities and ethnic minorities. Addressing these issues will require coordinated action with these communities.
CURRENT OPINION IN CRITICAL CARE
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Marina Del Rios, Brahmajee K. Nallamothu, Paul S. Chan
CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES
(2023)
Editorial Material
Critical Care Medicine
Sarah M. Perman, Melissa A. Vogelsong, Marina Del Rios
Article
Anesthesiology
Aditya C. Shekhar, Ryan A. Coute, Timothy J. Mader, Marina Del Rios, Katherine R. Peeler, N. Clay Mann, Manu Madhok
Summary: This study investigates disparities in endotracheal intubation success rates among infants experiencing out-of-hospital cardiac arrest (OHCA) based on race/ethnicity and sex. Analyzing data from a national-level registry, the study finds that white infants have higher success rates compared to Black or African American infants and Hispanic/Latino infants. Female infants also show slightly higher success rates than male infants. These findings highlight important demographic disparities in infant OHCA resuscitation and call for further research to identify the underlying reasons and develop strategies to eliminate these disparities.
TRENDS IN ANAESTHESIA AND CRITICAL CARE
(2023)
Review
Cardiac & Cardiovascular Systems
Daniel C. Schroeder, Federico Semeraro, Robert Greif, Janet Bray, Peter Morley, Michael Parr, Naomi Kondo Nakagawa, Taku Iwami, Simon-Richard Finke, Carolina Malta Hansen, Andrew Lockey, Marina Del Rios, Farhan Bhanji, Comilla Sasson, Stephen M. Schexnayder, Tommaso Scquizzato, Wolfgang A. Wetsch, Bernd W. Bottiger
Summary: Based on existing literature, schoolchildren show high motivation to learn basic life support. It is recommended to use the CHECK-CALL-COMPRESS algorithm for all students and provide regular training. Young children from 4 years old can assess the first links in the chain of survival, while older students can achieve effective chest compressions and ventilation volumes. A combination of theoretical and practical training is recommended, with schoolteachers serving as effective instructors.
Editorial Material
Critical Care Medicine
Marina Del Rios
Article
Medicine, General & Internal
Esther K. Choo, Matthew Strehlow, Marina Del Rios, Evrim Oral, Ruth Pobee, Andrew Nugent, Stephen Lim, Christian Hext, Sarah Newhall, Diana Ko, Srihari Chari, Amy Wilson, Joshua J. Baugh, David Callaway, Mucio Kit Delgado, Zoe Glick, Christian J. Graulty, Nicholas Hall, Abdusebur Jemal, Madhav Kc, Aditya Mahadevan, Milap Mehta, Andrew C. Meltzer, Dar'ya Pozhidayeva, Daniel Resnick-Ault, Christian Schulz, Sam Shen, Lauren Southerland, Daniel Du Pont, Danielle M. McCarthy
Summary: This study examined the operational approaches taken by US hospitals in response to the COVID-19 pandemic over a one-year period. The findings showed variation in strategy uptake over time, with some strategies related to geographic region and phase of the pandemic. The study identified commonly used and sustained strategies, such as limiting staff in COVID-19 rooms and increasing telehealth capacity, as well as strategies that were rarely used or not sustained, such as increasing hospital bed capacity.
Editorial Material
Medicine, General & Internal
Ryan Huebinger, Marina Del Rios
Article
Critical Care Medicine
Pavitra Kotini-Shah, Nicole Blum, Shaveta Khosla, Joseph Weber, Eddie Markul, Katie Tataris, Teri Campbell, Terry Vanden Hoek, Marina Del Rios
Summary: The survival rate of out-of-hospital cardiac arrest (OHCA) varies widely across the United States. The impact of hospital OHCA volume and ST-elevation myocardial infarction (STEMI) Receiving Center (SRC) designation on survival is not fully understood.
RESUSCITATION PLUS
(2023)
Article
Cardiac & Cardiovascular Systems
Ryan Huebinger, Marina Del Rios, Benjamin S. Abella, Bryan McNally, Carrie Bakunas, Richard Witkov, Micah Panczyk, Eric Boerwinkle, Bentley Bobrow
Summary: This study evaluated the impact of receiving hospital on outcome disparities in out-of-hospital cardiac arrest patients. The results showed that patients in Black and Hispanic or Latino communities were less likely to be treated at higher-performing hospitals, and adjusting for receiving hospital improved outcome disparities in out-of-hospital cardiac arrest.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Review
Critical Care Medicine
Daniel C. Schroeder, Federico Semeraro, Robert Greif, Janet Bray, Peter Morley, Michael Parr, Naomi Kondo Nakagawa, Taku Iwami, Simon-Richard Finke, Carolina Malta Hansen, Andrew Lockey, Marina Del Rios, Farhan Bhanji, Comilla Sasson, Stephen M. Schexnayder, Tommaso Scquizzato, Wolfgang A. Wetsch, Bernd W. Boettiger, International Liaison Committee Resuscitation
Summary: Teaching schoolchildren basic life support is an effective way to increase bystander CPR rates. Students are motivated to learn and regular training consolidates long-term skills. Schoolteachers serve as effective instructors and social media tools can be used for teaching.
Article
Critical Care Medicine
Veerle Heesters, Janneke Dekker, Timothy J. R. Panneflek, Kristel L. A. M. Kuypers, Stuart B. Hooper, Remco Visser, Arjan B. te Pas
Summary: This study visualized the closure of vocal cords during apnea, in between breaths, and during breath holds in preterm infants using ultrasonography. The closure of vocal cords impaired the effect of respiratory support.