2-hydroxyglutarate inhibits MyoD-mediated differentiation by preventing H3K9 demethylation
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
2-hydroxyglutarate inhibits MyoD-mediated differentiation by preventing H3K9 demethylation
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 116, Issue 26, Pages 12851-12856
Publisher
Proceedings of the National Academy of Sciences
Online
2019-06-11
DOI
10.1073/pnas.1817662116
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
- (2019) Abhishek A. Chakraborty et al. SCIENCE
- The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma
- (2018) Matthew J. McBride et al. CANCER CELL
- An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
- (2017) M Ryan Corces et al. NATURE METHODS
- Dynamics of BAF–Polycomb complex opposition on heterochromatin in normal and oncogenic states
- (2016) Cigall Kadoch et al. NATURE GENETICS
- H3K9me3-Dependent Heterochromatin: Barrier to Cell Fate Changes
- (2016) Justin S. Becker et al. TRENDS IN GENETICS
- Presence of isocitrate dehydrogenase mutations may predict clinical response to hypomethylating agents in patients with acute myeloid leukemia
- (2015) Ashkan Emadi et al. AMERICAN JOURNAL OF HEMATOLOGY
- Insulator dysfunction and oncogene activation in IDH mutant gliomas
- (2015) William A. Flavahan et al. NATURE
- DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia
- (2015) Chun-Wei Chen et al. NATURE MEDICINE
- Unique mutation portraits and frequentCOL2A1gene alteration in chondrosarcoma
- (2014) Yasushi Totoki et al. GENOME RESEARCH
- Induction of sarcomas by mutant IDH2
- (2013) C. Lu et al. GENES & DEVELOPMENT
- Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
- (2013) Jason D Buenrostro et al. NATURE METHODS
- Step-Wise Methylation of Histone H3K9 Positions Heterochromatin at the Nuclear Periphery
- (2012) Benjamin D. Towbin et al. CELL
- TET2 Mutations in Acute Myeloid Leukemia (AML): Results From a Comprehensive Genetic and Clinical Analysis of the AML Study Group
- (2012) Verena I. Gaidzik et al. JOURNAL OF CLINICAL ONCOLOGY
- IDH mutation impairs histone demethylation and results in a block to cell differentiation
- (2012) Chao Lu et al. NATURE
- Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
- (2012) Peppi Koivunen et al. NATURE
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA
- (2011) Marcella Cesana et al. CELL
- The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
- (2011) Rasheduzzaman Chowdhury et al. EMBO REPORTS
- IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours
- (2011) M Fernanda Amary et al. JOURNAL OF PATHOLOGY
- Genomic Prevalence of Heterochromatic H3K9me2 and Transcription Do Not Discriminate Pluripotent from Terminally Differentiated Cells
- (2011) Florian Lienert et al. PLoS Genetics
- The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
- (2010) Patrick S. Ward et al. CANCER CELL
- Expression and subcellular localization of myogenic regulatory factors during the differentiation of skeletal muscle C2C12 myoblasts
- (2009) Paola Ferri et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
- (2009) Lenny Dang et al. NATURE
- Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells
- (2009) Bo Wen et al. NATURE GENETICS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now