GTS-21 has cell-specific anti-inflammatory effects independent of α7 nicotinic acetylcholine receptors

Evaluating Commercially Available Antibodies for Rat α7 Nicotinic Acetylcholine Receptors

(2017) Brijesh K. Garg et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Anti-inflammatory Silent Agonists

(2017) Nicole A. Horenstein et al.   ACS Medicinal Chemistry Letters

Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis

(2016) Frieda A. Koopman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EFFECT OF GTS-21, AN ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONIST, ON CLP-INDUCED INFLAMMATORY, GASTROINTESTINAL MOTILITY, AND COLONIC PERMEABILITY CHANGES IN MICE

(2016) Sara Nullens et al.   SHOCK

Alpha7 nicotinic receptors as therapeutic targets for Parkinson's disease

(2015) Maryka Quik et al.   BIOCHEMICAL PHARMACOLOGY

Phosphocholine-Modified Macromolecules and Canonical Nicotinic Agonists Inhibit ATP-Induced IL-1β Release

(2015) Andreas Hecker et al.   JOURNAL OF IMMUNOLOGY

?7-Nicotinic Receptors and Cognition

(2013) Edward D. Levin   CURRENT DRUG TARGETS

Contribution of  7 nicotinic receptor to airway epithelium dysfunction under nicotine exposure

(2013) K. Maouche et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reflex Principles of Immunological Homeostasis

(2012) Ulf Andersson et al.   Annual Review of Immunology

Cell-specific effects on surface α7 nicotinic receptor expression revealed by over-expression and knockdown of rat RIC3 protein

(2012) Thomas M. Koperniak et al.   JOURNAL OF NEUROCHEMISTRY

The α7 nicotinic acetylcholine receptor ligands methyllycaconitine, NS6740 and GTS-21 reduce lipopolysaccharide-induced TNF-α release from microglia

(2012) Morten S. Thomsen et al.   JOURNAL OF NEUROIMMUNOLOGY

Nicotinic Acetylcholine Receptor Agonists Attenuate Septic Acute Kidney Injury in Mice by Suppressing Inflammation and Proteasome Activity

(2012) Prodyot K. Chatterjee et al.   PLoS One

Lipopolysaccharide Upregulates α7 Acetylcholine Receptors

(2012) Mohammed Abdul Sattar Khan et al.   SHOCK

Modulation of inflammatory pathways by the immune cholinergic system

(2011) Eran Nizri et al.   AMINO ACIDS

Anatabine lowers Alzheimer's Aβ production in vitro and in vivo

(2011) Daniel Paris et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Pyrrolidine dithiocarbamate inhibits nuclear factor- B pathway activation, and regulates adhesion, migration, invasion and apoptosis of endometriotic stromal cells

(2010) J.-j. Zhang et al.   MOLECULAR HUMAN REPRODUCTION

 4 2 Nicotinic Receptors Partially Mediate Anti-Inflammatory Effects through Janus Kinase 2-Signal Transducer and Activator of Transcription 3 but Not Calcium or cAMP Signaling

(2010) V. Hosur et al.   MOLECULAR PHARMACOLOGY

Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice

(2009) Marjolein A. van Maanen et al.   ARTHRITIS AND RHEUMATISM

GTS-21 inhibits pro-inflammatory cytokine release independent of the Toll-like receptor stimulated via a transcriptional mechanism involving JAK2 activation

(2009) Matthijs Kox et al.   BIOCHEMICAL PHARMACOLOGY

Vagus Nerve Activity Augments Intestinal Macrophage Phagocytosis via Nicotinic Acetylcholine Receptor α4β2

(2009) Esmerij P. van der Zanden et al.   GASTROENTEROLOGY

The genetics of chronic inflammatory diseases

(2009) G. A. Heap et al.   HUMAN MOLECULAR GENETICS

Old and New Pharmacology: Positive Allosteric Modulation of the  7 Nicotinic Acetylcholine Receptor by the 5-Hydroxytryptamine2B/C Receptor Antagonist SB-206553 (3,5-Dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']di pyrrole-1(2H)-carboxamide)

(2008) J. Dunlop et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation

(2007) W J Jonge et al.   BRITISH JOURNAL OF PHARMACOLOGY