Null mutation of the endothelin receptor type B gene causes embryonic death in the GK rat

Exposure to GDNF Enhances the Ability of Enteric Neural Progenitors to Generate an Enteric Nervous System

(2017) Sonja J. McKeown et al.   Stem Cell Reports

Enhancer Variants Synergistically Drive Dysfunction of a Gene Regulatory Network In Hirschsprung Disease

(2016) Sumantra Chatterjee et al.   CELL

Genetic variation in the GDNF promoter affects its expression and modifies the severity of Hirschsprung's disease (HSCR) in rats carrying Ednrbsl mutations

(2016) Jieping Huang et al.   GENE

Identification of Genetic Loci Affecting the Severity of Symptoms of Hirschsprung Disease in Rats Carrying Ednrbsl Mutations by Quantitative Trait Locus Analysis

(2015) Jieping Huang et al.   PLoS One

Simple knockout by electroporation of engineered endonucleases into intact rat embryos

(2014) Takehito Kaneko et al.   Scientific Reports

The enteric nervous system

(2012) Valentina Sasselli et al.   DEVELOPMENTAL BIOLOGY

Novel mutations at RET ligand genes preventing receptor activation are associated to Hirschsprung’s disease

(2011) Macarena Ruiz-Ferrer et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Copy Number Variants in Candidate Genes Are Genetic Modifiers of Hirschsprung Disease

(2011) Qian Jiang et al.   PLoS One

Genetic Background Strongly Modifies the Severity of Symptoms of Hirschsprung Disease, but Not Hearing Loss in Rats Carrying Ednrbsl Mutations

(2011) Ruihua Dang et al.   PLoS One

QTL Analysis Identifies a Modifier Locus of Aganglionosis in the Rat Model of Hirschsprung Disease Carrying Ednrbsl Mutations

(2011) Ruihua Dang et al.   PLoS One