A system for site-specific integration of transgenes in mammalian cells

Cloning of CHO Cells, Productivity and Genetic Stability—A Discussion

(2017) Florian Wurm et al.   Processes

Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time

(2016) Julia Feichtinger et al.   BIOTECHNOLOGY AND BIOENGINEERING

CRISPR/Cas9-mediated genome engineering of CHO cell factories: Application and perspectives

(2015) Jae Seong Lee et al.   Biotechnology Journal

Homologous Recombination-Independent Large Gene Cassette Knock-in in CHO Cells Using TALEN and MMEJ-Directed Donor Plasmids

(2015) Tetsushi Sakuma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MMEJ-assisted gene knock-in using TALENs and CRISPR-Cas9 with the PITCh systems

(2015) Tetsushi Sakuma et al.   Nature Protocols

CRISPR/Cas9-mediated genome engineering of CHO cell factories: Application and perspectives

(2015) Jae Seong Lee et al.   Biotechnology Journal

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Recombinase-mediated cassette exchange (RMCE) — A rapidly-expanding toolbox for targeted genomic modifications

(2012) Soeren Turan et al.   GENE

The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

(2011) Xun Xu et al.   NATURE BIOTECHNOLOGY

Site-specific integrase-mediated transgenesis in mice via pronuclear injection

(2011) B. Tasic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly efficient deletion of FUT8 in CHO cell lines using zinc-finger nucleases yields cells that produce completely nonfucosylated antibodies

(2010) Laetitia Malphettes et al.   BIOTECHNOLOGY AND BIOENGINEERING

Generation of stable cell lines by site-specific integration of transgenes into engineered Chinese hamster ovary strains using an FLP-FRT system

(2010) Hong Zhou et al.   JOURNAL OF BIOTECHNOLOGY