4.8 Article

Metal-Free Visible-Light-Induced Construction of Difluoro-Containing Dibenzazepines

Journal

ORGANIC LETTERS
Volume 21, Issue 12, Pages 4745-4749

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b01629

Keywords

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Funding

  1. NSFC [21632003, 21871116, 21572087]
  2. key program of Gansu Province [17ZD2GC011]
  3. 111 program from the MOE, P.R. China

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A metal-free photocatalytic protocol for efficient construction of difluoro-containing dibenzazepines is developed. The transformation is redox-neutral and environmentally benign, has a wide range of substrate scope, proceeds at room temperature under irradiation of visible light, and furnishes dibenzazepine derivatives in mild to excellent yield.

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