Melatonin Enhances Autophagy and Reduces Apoptosis to Promote Locomotor Recovery in Spinal Cord Injury via the PI3K/AKT/mTOR Signaling Pathway
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Melatonin Enhances Autophagy and Reduces Apoptosis to Promote Locomotor Recovery in Spinal Cord Injury via the PI3K/AKT/mTOR Signaling Pathway
Authors
Keywords
Spinal cord injury, Melatonin, Autophagy, PI3K, AKT, mTOR signaling pathway
Journal
NEUROCHEMICAL RESEARCH
Volume 44, Issue 8, Pages 2007-2019
Publisher
Springer Science and Business Media LLC
Online
2019-07-20
DOI
10.1007/s11064-019-02838-w
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- bFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats
- (2018) Dawei Sun et al. Cell Death & Disease
- Minocycline targets multiple secondary injury mechanisms in traumatic spinal cord injury
- (2017) Yinghui Zhong et al. Neural Regeneration Research
- Melatonin Inhibits Neural Cell Apoptosis and Promotes Locomotor Recovery via Activation of the Wnt/β-Catenin Signaling Pathway After Spinal Cord Injury
- (2017) Zhaoliang Shen et al. NEUROCHEMICAL RESEARCH
- Resveratrol protects against spinal cord injury by activating autophagy and inhibiting apoptosis mediated by the SIRT1/AMPK signaling pathway
- (2017) Haosen Zhao et al. NEUROSCIENCE
- Effects of melatonin on spinal cord injury-induced oxidative damage in mice testis
- (2016) X.-C. Yuan et al. ANDROLOGIA
- Heme oxygenase-1 protects spinal cord neurons from hydrogen peroxide-induced apoptosis via suppression of Cdc42/MLK3/MKK7/JNK3 signaling
- (2016) Siyuan Wang et al. APOPTOSIS
- Metformin preconditioning provide neuroprotection through enhancement of autophagy and suppression of inflammation and apoptosis after spinal cord injury
- (2016) Chen Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Reducing synuclein accumulation improves neuronal survival after spinal cord injury
- (2016) Stephanie M. Fogerson et al. EXPERIMENTAL NEUROLOGY
- Simvastatin inhibits neural cell apoptosis and promotes locomotor recovery via activation of Wnt/β-catenin signaling pathway after spinal cord injury
- (2016) Kai Gao et al. JOURNAL OF NEUROCHEMISTRY
- Melatonin for Spinal Cord Injury in Animal Models: A Systematic Review and Network Meta-Analysis
- (2016) Long Yang et al. JOURNAL OF NEUROTRAUMA
- Probucol inhibits neural cell apoptosis via inhibition of mTOR signaling pathway after spinal cord injury
- (2016) Zipeng Zhou et al. NEUROSCIENCE
- VEGF inhibits the inflammation in spinal cord injury through activation of autophagy
- (2015) Hongyu Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The effect of concentration and duration of normobaric oxygen in reducing caspase-3 and -9 expression in a rat-model of focal cerebral ischaemia
- (2015) Suyan Chen et al. BRAIN RESEARCH
- Drug delivery, cell-based therapies, and tissue engineering approaches for spinal cord injury
- (2015) Shushi Kabu et al. JOURNAL OF CONTROLLED RELEASE
- Acute Spinal Cord Injury
- (2015) Christopher D. Witiw et al. JOURNAL OF SPINAL DISORDERS & TECHNIQUES
- Exercise promotes motor functional recovery in rats with corticospinal tract injury: anti-apoptosis mechanism
- (2015) Xiao-yu Yang et al. Neural Regeneration Research
- Neuroprotective effect of rapamycin on spinal cord injury via activation of the Wnt/β-catenin signaling pathway
- (2015) Pei-fu Tang et al. Neural Regeneration Research
- Melatonin protects the brain from apoptosis by enhancement of autophagy after traumatic brain injury in mice
- (2015) Ke Ding et al. NEUROCHEMISTRY INTERNATIONAL
- Melatonin: Physiological effects in humans
- (2015) B. Claustrat et al. NEUROCHIRURGIE
- Hyperbaric oxygen therapy improves local microenvironment after spinal cord injury
- (2015) Yajun Li et al. Neural Regeneration Research
- Beclin-1-mediated autophagy protects spinal cord neurons against mechanical injury-induced apoptosis
- (2014) Zhen-Yu Wang et al. APOPTOSIS
- Melatonin Inhibits mTOR-Dependent Autophagy during Liver Ischemia/Reperfusion
- (2014) Jung-Woo Kang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Beneficial Effects of Melatonin Combined with Exercise on Endogenous Neural Stem/Progenitor Cells Proliferation after Spinal Cord Injury
- (2014) Youngjeon Lee et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Neuroprotective Effects of Autophagy Induced by Rapamycin in Rat Acute Spinal Cord Injury Model
- (2014) Zhen-Yu Wang et al. NEUROIMMUNOMODULATION
- Effects of CDNF on 6-OHDA-induced apoptosis in PC12 cells via modulation of Bcl-2/Bax and caspase-3 activation
- (2014) Jia-ming Mei et al. NEUROLOGICAL SCIENCES
- Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: The role of inhibition of Drp1 in ischemic brain damage
- (2014) Wei Zuo et al. NEUROPHARMACOLOGY
- Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAFV600E inhibition and can be targeted to reduce resistance
- (2014) M N Serasinghe et al. ONCOGENE
- Epidemiology of Spinal Cord Injuries and Risk Factors for Complete Injuries in Guangdong, China: A Retrospective Study
- (2014) Rui Yang et al. PLoS One
- Historical landmarks of autophagy research
- (2013) Yoshinori Ohsumi CELL RESEARCH
- Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction
- (2012) Shihui Xing et al. Autophagy
- Multifaceted effects of rapamycin on functional recovery after spinal cord injury in rats through autophagy promotion, anti-inflammation, and neuroprotection
- (2012) Hsien-Chih Chen et al. JOURNAL OF SURGICAL RESEARCH
- Rapamycin Promotes Autophagy and Reduces Neural Tissue Damage and Locomotor Impairment after Spinal Cord Injury in Mice
- (2011) Akira Sekiguchi et al. JOURNAL OF NEUROTRAUMA
- Beneficial effects of endogenous and exogenous melatonin on neural reconstruction and functional recovery in an animal model of spinal cord injury
- (2011) Sookyoung Park et al. JOURNAL OF PINEAL RESEARCH
- Insulin promotes dendritic spine and synapse formation by the PI3K/Akt/mTOR and Rac1 signaling pathways
- (2011) Cheng-Che Lee et al. NEUROPHARMACOLOGY
- Autophagy in Alzheimer’s disease
- (2010) Paula I Moreira et al. Expert Review of Neurotherapeutics
- Neurons derived from transplanted neural stem cells restore disrupted neuronal circuitry in a mouse model of spinal cord injury
- (2010) Masahiko Abematsu et al. JOURNAL OF CLINICAL INVESTIGATION
- The role of autophagy in spinal cord injury
- (2009) Haruo Kanno et al. Autophagy
- Melatonin and Reproduction Revisited
- (2009) Russel J. Reiter et al. BIOLOGY OF REPRODUCTION
- The PI3K-Akt-mTOR pathway regulates Aβ oligomer induced neuronal cell cycle events
- (2009) Kiran Bhaskar et al. Molecular Neurodegeneration
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now