Systemic peptide mediated delivery of an siRNA targeting α-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy body disease

Published 2019 View Full Article

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Title
Systemic peptide mediated delivery of an siRNA targeting α-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy body disease
Authors
Keywords
Parkinson's disease, siRNA, Blood-brain barrier, α-Synuclein, Low density lipoprotein receptor, Apolipoprotein B, Receptor mediated transytosis
Journal
NEUROBIOLOGY OF DISEASE
Volume 127, Issue -, Pages 163-177
Publisher
Elsevier BV
Online
2019-03-06
DOI
10.1016/j.nbd.2019.03.001

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