Telmisartan attenuates N-nitrosodiethylamine-induced hepatocellular carcinoma in mice by modulating the NF-κB-TAK1-ERK1/2 axis in the context of PPARγ agonistic activity
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Title
Telmisartan attenuates N-nitrosodiethylamine-induced hepatocellular carcinoma in mice by modulating the NF-κB-TAK1-ERK1/2 axis in the context of PPARγ agonistic activity
Authors
Keywords
Telmisartan, N-Nitrosodiethylamine, PPARγ, ERK1/2, TAK1, NF-кB
Journal
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-07-31
DOI
10.1007/s00210-019-01706-2
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Note: Only part of the references are listed.- Renin–angiotensin system inhibition ameliorates CCl4-induced liver fibrosis in mice through the inactivation of nuclear transcription factor kappa B
- (2018) Sameh Saber et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Perindopril, fosinopril and losartan inhibited the progression of diethylnitrosamine-induced hepatocellular carcinoma in mice via the inactivation of nuclear transcription factor kappa-B
- (2018) Sameh Saber et al. TOXICOLOGY LETTERS
- MTBP inhibits the Erk1/2-Elk-1 signaling in hepatocellular carcinoma
- (2018) Atul Ranjan et al. Oncotarget
- Lisinopril inhibits nuclear transcription factor kappa B and augments sensitivity to silymarin in experimental liver fibrosis
- (2018) Sameh Saber et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Olmesartan ameliorates chemically-induced ulcerative colitis in rats via modulating NFκB and Nrf-2/HO-1 signaling crosstalk
- (2018) Sameh Saber et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Sorafenib controls the epithelial-mesenchymal transition of ovarian cancer cells via EGF and the CD44-HA signaling pathway in a cell type-dependent manner
- (2017) Ga Bin Park et al. Molecular Medicine Reports
- Losartan Attenuates Myocardial Endothelial-To-Mesenchymal Transition in Spontaneous Hypertensive Rats via Inhibiting TGF-β/Smad Signaling
- (2016) Miao Wu et al. PLoS One
- Losartan Effect on lowering TNF-α Serum Levels in Asymptomatic Hyperuricemia Hypertension Patients
- (2015) Z. Ali et al. JOURNAL OF HYPERTENSION
- Calligonum comosum extract inhibits diethylnitrosamine-induced hepatocarcinogenesis in rats
- (2015) WALIED ABDO et al. Oncology Letters
- Cross-talk between heme oxygenase and peroxisome proliferator-activated receptors in the regulation of physiological functions
- (2014) Joseph et al. Frontiers in Bioscience-Landmark
- Telmisartan Induces Growth Inhibition, DNA Double-Strand Breaks and Apoptosis in Human Endometrial Cancer Cells
- (2014) Naoko Koyama et al. PLoS One
- Virus associated malignancies: The role of viral hepatitis in hepatocellular carcinoma
- (2014) Amir Shlomai et al. SEMINARS IN CANCER BIOLOGY
- TNF and MAP kinase signalling pathways
- (2014) Guadalupe Sabio et al. SEMINARS IN IMMUNOLOGY
- Antiproliferative and apoptotic effects of telmisartan in human colon cancer cells
- (2014) LUCAS D. LEE et al. Oncology Letters
- Combined effects of organochlorine pesticides heptachlor and hexachlorobenzene on the promotion stage of hepatocarcinogenesis in rats
- (2013) Walied Abdo et al. FOOD AND CHEMICAL TOXICOLOGY
- Immunomodulatory Effect of Stichopus japonicus Acid Mucopolysaccharide on Experimental Hepatocellular Carcinoma in Rats
- (2013) Yang Song et al. MOLECULES
- The human sulfatase 2 inhibitor 2,4-disulfonylphenyl-tert-butylnitrone (OKN-007) has an antitumor effect in hepatocellular carcinoma mediated via suppression of TGFB1/SMAD2 and Hedgehog/GLI1 signaling
- (2012) Xin Zheng et al. GENES CHROMOSOMES & CANCER
- Diethylnitrosamine-induced hepatocarcinogenesis is suppressed in lecithin:retinol acyltransferase-deficient mice primarily through retinoid actions immediately after carcinogen administration
- (2011) Y. Shirakami et al. CARCINOGENESIS
- PPARγ inhibits NF-κB-dependent transcriptional activation in skeletal muscle
- (2009) A. H. V. Remels et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Angiotensin II receptor blockade improves matrix metalloproteinases/tissue inhibitor of matrix metalloproteinase-1 balance and restores fibronectin expression in rat infarcted myocardium
- (2009) Dachun Yang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Prognostic role of vascular endothelial growth factor in hepatocellular carcinoma: systematic review and meta-analysis
- (2009) S J Schoenleber et al. BRITISH JOURNAL OF CANCER
- To scale or not to scale: the principles of dose extrapolation
- (2009) Vijay Sharma et al. BRITISH JOURNAL OF PHARMACOLOGY
- Angiotensin inhibition and malignancies: a review
- (2009) T Rosenthal et al. JOURNAL OF HUMAN HYPERTENSION
- Potential role of Renin–Angiotensin-system for tumor angiogenesis in receptor negative breast cancer
- (2008) D. Herr et al. GYNECOLOGIC ONCOLOGY
- Association of ACE Inhibitors and Angiotensin Receptor Blockers with Keratinocyte Cancer Prevention in the Randomized VATTC Trial
- (2008) J. B. Christian et al. JNCI-Journal of the National Cancer Institute
- Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-κB activation via NADPH oxidase
- (2007) Yongzhong Wei et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
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