Journal
NATURAL PRODUCT RESEARCH
Volume 35, Issue 2, Pages 195-202Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2019.1619723
Keywords
Hypericum choisianum; PPAPs; Hyperichoisins A - C; NMR analysis
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Funding
- National Science & Technology Major Project Key New Drug Creation and Manufacturing Program [2018ZX09201001-001-005, 2018ZX09201001-001-007, 2018ZX09735001-002-005]
- Ministry of Science and Technology, China
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Twenty-one polycyclic polyprenylated acylphloroglucinols, including three new compounds named hyperichoisins A (3), B (14) and C (21), were isolated from the aerial parts of Hypericum choisianum. The structures of those new compounds were determined through analysis of mass, NMR data, and chiroptical properties. A bioassay showed that otogirinin B exhibited significant inhibitory effect on cell proliferation of A549.
Twenty-one polycyclic polyprenylated acylphloroglucinols, including three new compounds named as hyperichoisins A (3), B (14) and C (21), were isolated from the aerial parts of Hypericum choisianum. The structures of those new compounds were elucidated by analysis of mass, NMR data, and chiroptical properties. A bioassay showed that otogirinin B had significant inhibitory effect on cell proliferation of A549.
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