T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug Etoposide

Formation and biological targets of botanical o-quinones

(2018) Judy L. Bolton et al.   FOOD AND CHEMICAL TOXICOLOGY

Two-Mechanism Model for the Interaction of Etoposide Quinone with Topoisomerase IIα

(2016) Elizabeth G. Gibson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Formation and Biological Targets of Quinones: Cytotoxic versus Cytoprotective Effects

(2016) Judy L. Bolton et al.   CHEMICAL RESEARCH IN TOXICOLOGY

TC-PTP and PTP1B: Regulating JAK–STAT signaling, controlling lymphoid malignancies

(2016) Kelly A. Pike et al.   CYTOKINE

Quinone-induced protein modifications: Kinetic preference for reaction of 1,2-benzoquinones with thiol groups in proteins

(2016) Yuting Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

A RP-UFLC Assay for Protein Tyrosine Phosphatases: Focus on Protein Tyrosine Phosphatase Non-Receptor Type 2 (PTPN2)

(2015) Romain Duval et al.   Scientific Reports

Topoisomerase II and leukemia

(2014) MaryJean Pendleton et al.   Annals of the New York Academy of Sciences

Etoposide Quinone Is a Covalent Poison of Human Topoisomerase IIβ

(2014) Nicholas A. Smith et al.   BIOCHEMISTRY

1,4-Naphthoquinones: From Oxidative Damage to Cellular and Inter-Cellular Signaling

(2014) Lars-Oliver Klotz et al.   MOLECULES

STAT transcription factors in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention

(2013) K A Dorritie et al.   LEUKEMIA

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Strain-Dependent Differences in Bone Development, Myeloid Hyperplasia, Morbidity and Mortality in Ptpn2-Deficient Mice

(2012) Florian Wiede et al.   PLoS One

Etoposide Quinone Is a Redox-Dependent Topoisomerase II Poison

(2011) David A. Jacob et al.   BIOCHEMISTRY

PTPN2 negatively regulates oncogenic JAK1 in T-cell acute lymphoblastic leukemia

(2011) M. Kleppe et al.   BLOOD

Mutation analysis of the tyrosine phosphatase PTPN2 in Hodgkin's lymphoma and T-cell non-Hodgkin's lymphoma

(2011) M. Kleppe et al.   HAEMATOLOGICA

Regulation of protein tyrosine phosphatases by reversible oxidation

(2011) Arne Östman et al.   JOURNAL OF BIOCHEMISTRY

Myeloperoxidase-Dependent Oxidation of Etoposide in Human Myeloid Progenitor CD34+ Cells

(2010) I. I. Vlasova et al.   MOLECULAR PHARMACOLOGY

Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia

(2010) Maria Kleppe et al.   NATURE GENETICS

Coordinating the Two Protomer Active Sites of Human Topoisomerase IIα: Nicks as Topoisomerase II Poisons†

(2009) Joseph E. Deweese et al.   BIOCHEMISTRY

TC-PTP is required for the maintenance of MYC-driven B-cell lymphomas

(2009) R. M. Young et al.   BLOOD

DNA-AP sites generation by Etoposide in whole blood cells

(2009) Emilio Rojas et al.   BMC CANCER

Targeting Signal Transducer and Activator of Transcription Signaling Pathway in Leukemias

(2009) Mustafa Benekli et al.   JOURNAL OF CLINICAL ONCOLOGY

Protein tyrosine phosphatases PTP-1B and TC-PTP play nonredundant roles in macrophage development and IFN-  signaling

(2009) K. M. Heinonen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA