Influence of Matrix Metallopeptidase 9 on Beta-Amyloid Elimination Across the Blood-Brain Barrier

Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury

(2018) Bevan S. Main et al.   Molecular Neurodegeneration

EFAD transgenic mice as a human APOE relevant preclinical model of Alzheimer’s disease

(2017) Leon M. Tai et al.   JOURNAL OF LIPID RESEARCH

Endothelial LRP1 – A Potential Target for the Treatment of Alzheimer’s Disease

(2017) Steffen E. Storck et al.   PHARMACEUTICAL RESEARCH

ApoE Influences the Blood-Brain Barrier Through the NF-κB/MMP-9 Pathway After Traumatic Brain Injury

(2017) Zhipeng Teng et al.   Scientific Reports

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Accelerated pericyte degeneration and blood–brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer’s disease

(2015) Matthew R Halliday et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Apolipoprotein E Isoform-Specific Effects on Lipoprotein Receptor Processing

(2014) Corbin Bachmeier et al.   NEUROMOLECULAR MEDICINE

Blood Levels of Glial Fibrillary Acidic Protein (GFAP) in Patients with Neurological Diseases

(2013) Christoph A. Mayer et al.   PLoS One

APOE4-specific Changes in Aβ Accumulation in a New Transgenic Mouse Model of Alzheimer Disease

(2012) Katherine L. Youmans et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stimulation of the Retinoid X Receptor Facilitates Beta-Amyloid Clearance Across the Blood–Brain Barrier

(2012) Corbin Bachmeier et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia

(2012) Jiankun Cui et al.   Molecular Neurodegeneration

Apolipoprotein E controls cerebrovascular integrity via cyclophilin A

(2012) Robert D. Bell et al.   NATURE

A Multifaceted Role for apoE in the Clearance of Beta-Amyloid across the Blood-Brain Barrier

(2012) Corbin Bachmeier et al.   Neurodegenerative Diseases

Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood A  clearance in a mouse model of  -amyloidosis

(2012) J. M. Castellano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell cholesterol modulates metalloproteinase-dependent shedding of low-density lipoprotein receptor-related protein-1 (LRP-1) and clearance function

(2011) Charlotte Selvais et al.   FASEB JOURNAL

Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice

(2011) Markus Krohn et al.   JOURNAL OF CLINICAL INVESTIGATION

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(2011) Daniel Paris et al.   MOLECULAR MEDICINE

Human apoE Isoforms Differentially Regulate Brain Amyloid-  Peptide Clearance

(2011) J. M. Castellano et al.   Science Translational Medicine

Amyloid-β Contributes to Blood–Brain Barrier Leakage in Transgenic Human Amyloid Precursor Protein Mice and in Humans With Cerebral Amyloid Angiopathy

(2011) Anika M.S. Hartz et al.   STROKE

Characterization and use of human brain microvascular endothelial cells to examine β-amyloid exchange in the blood-brain barrier

(2010) Corbin Bachmeier et al.   CYTOTECHNOLOGY

Alzheimer's disease: strategies for disease modification

(2010) Martin Citron   NATURE REVIEWS DRUG DISCOVERY

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Metalloproteinase-Dependent Shedding of Low-Density Lipoprotein Receptor-Related Protein-1 Ectodomain Decreases Endocytic Clearance of Endometrial Matrix Metalloproteinase-2 and -9 at Menstruation

(2009) Charlotte Selvais et al.   ENDOCRINOLOGY

Human APOE Isoform-Dependent Effects on Brain  -Amyloid Levels in PDAPP Transgenic Mice

(2009) K. R. Bales et al.   JOURNAL OF NEUROSCIENCE

Matrix Metalloprotease-9 Inhibition Improves Amyloid  -Mediated Cognitive Impairment and Neurotoxicity in Mice

(2009) H. Mizoguchi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Role of Apolipoprotein E in Alzheimer's Disease

(2009) Jungsu Kim et al.   NEURON

The Hemopexin Domain of Matrix Metalloproteinase-9 Activates Cell Signaling and Promotes Migration of Schwann Cells by Binding to Low-Density Lipoprotein Receptor-Related Protein

(2008) E. Mantuano et al.   JOURNAL OF NEUROSCIENCE